Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: Safety, pharmacokinetics and ammonia control
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References (9)
Urea Cycle Disorders: Diagnosis, Pathophysiology, and Therapy
1996 • 341 citations
Survival after Treatment with Phenylacetate and Benzoate for Urea-Cycle Disorders
2007 • 335 citations
Diagnosis, symptoms, frequency and mortality of 260 patients with urea cycle disorders from a 21‐year, multicentre study of acute hyperammonaemic episodes
2008 • 206 citations
Cross-sectional multicenter study of patients with urea cycle disorders in the United States
2008 • 202 citations
Phenylacetylglutamine May Replace Urea as a Vehicle for Waste Nitrogen Excretion
1991 • 165 citations
Clinical Consequences of Urea Cycle Enzyme Deficiencies and Potential Links to Arginine and Nitric Oxide Metabolism
2004 • 86 citations
NEW SECONDARY METABOLITES OF PHENYLBUTYRATE IN HUMANS AND RATS
2004 • 44 citations
Systemic hypertension in two patients with ASL deficiency: A result of nitric oxide deficiency?
2009 • 41 citations
Restoration of nitrogen homeostasis in a man with ornithine transcarbamylase deficiency
1993 • 31 citations