Aripiprazole, a novel antipsychotic drug, inhibits quinpriole-evoked GTPase activity but does not up-regulate dopamine D2 receptor following repeated treatment in the rat striatum

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Molecular biology of dopamine receptors

1992 • 998 citations

Alternative splicing directs the expression of two D2 dopamine receptor isoforms

1989 • 692 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

Dopamine receptor gene expression by enkephalin neurons in rat forebrain.

1990 • 469 citations

The Mechanism of Action of Novel Antipsychotic Drugs

1991 • 410 citations

D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

1989 • 322 citations

7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity.

1995 • 268 citations

Structures of Dopamine Receptors

1993 • 137 citations

New insights into dopamine receptors in the central nervous system

1993 • 108 citations

Behavioural and neurochemical effects of OPC-14597, a novel antipsychotic drug, on dopaminergic mechanisms in rat brain

1995 • 91 citations

Changes in dopamine D1, D2 and D3 receptor mRNA levels in rat brain following antipsychotic treatment

1992 • 78 citations

Functional Reconstitution of Purified G_i and G_o with μ‐Opioid Receptors in Guinea Pig Striatal Membranes Pretreated with Micromolar Concentrations of N‐Ethylmaleimide

1990 • 61 citations

Up-regulation of dopamine D2 receptor mRNA in rat striatum by chronic neuroleptic treatment

1991 • 57 citations

Central D1- and D2-receptor occupancy during antipsychotic drug treatment

1990 • 50 citations

Pharmacologic treatment of schizophrenia.

1991 • 43 citations

Clozapine and sulpiride up-regulate dopamine D3 receptor mRNA levels

1993 • 40 citations

Is 3-PPP a potential antipsychotic agent? Evidence from animal behavioural studies

1982 • 23 citations

Both splicing variants of the dopamine D2 receptor mRNA are up-regulated by antipsychotic drugs

1993 • 18 citations

Supersensitivity of quinpirole-evoked GTPase activation without changes in gene expression of D2 and Gi protein in the striatum of hemi-dopaminergic lesioned rats

1994 • 11 citations

Interactions of 7-[3-(4-[2,3-dimethylphenyl]piperazinyl)-propoxy]-2(1H)-quinolinone binding in rat striatum: effects of lesions.

1990 • 7 citations