Brown Adipose Tissue Thermogenesis in Obese Animals

Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline

1978 • 653 citations

Recent Advances in Obesity Research

1979 • 613 citations

Tissue distribution of cold-induced thermogenesis in conscious warm- or cold-acclimated rats reevaluated from changes in tissue blood flow: The dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis

1979 • 509 citations

Brown adipose tissue mitochondria

1979 • 369 citations

Effect of Diet and Cold Exposure on Norepinephrine Turnover in Brown Adipose Tissue of the Rat

1982 • 348 citations

The body weight regulatory system: normal and disturbed mechanisms.

1981 • 347 citations

Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus

1981 • 321 citations

Reduced thermogenesis in obesity

1979 • 296 citations

The Brown Fat Cell

1982 • 233 citations

Mitochondria and Microsomes

1982 • 223 citations

A mitochondrial defect in brown adipose tissue of the obese (obob) mouse: Reduced binding of purine nucleotides and a failure to respond to cold by an increase in binding

1978 • 212 citations

Regional blood flow in genetically obese (ob/ob) mice

1980 • 180 citations

Increased purine nucleotide binding, altered polypeptide composition, and thermogenesis in brown adipose tissue mitochondria of cold-acclimated rats

1978 • 179 citations

Imperfect Homeothermia in the Hereditary Obese-Hyperglycemic Syndrome of Mice

1954 • 175 citations

Thermic effect of glucose in obese subjects studied by direct and indirect calorimetry

1976 • 173 citations

Influence of noradrenaline on blood flow to brown adipose tissue in rats exhibiting diet-induced thermogenesis

1981 • 166 citations

Glucose-induced Thermogenesis in Nondiabetic and Diabetic Obese Subjects

1982 • 164 citations

Postprandial Thermogenesis in Obesity

1981 • 161 citations

Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis

1980 • 160 citations

REGULATION OF ENERGY BALANCE

1981 • 155 citations

Similarities between cold- and diet-induced thermogenesis in the rat

1980 • 152 citations

Fatty Acids as Acute Regulators of the Proton Conductance of Hamster Brown‐Fat Mitochondria

1982 • 140 citations

The role of thermoregulatory thermogenesis in the development of obesity in genetically-obese (ob/ob) mice pair-fed with lean siblings

1979 • 136 citations

Impaired Suppression of Sympathetic Activity during Fasting in the Gold Thioglucose-treated Mouse

1980 • 128 citations

Influence of mild cold on 24 h energy expenditure, resting metabolism and diet-induced thermogenesis

1981 • 126 citations

Roles of noradrenaline and protein synthesis in the cold-induced increase in purine nucleotide binding by rat brown adipose tissue mitochondria

1979 • 124 citations

Obesity may be due to a malfunctioning of brown fat.

1979 • 123 citations

The Adipocyte and obesity : cellular and molecular mechanisms

1983 • 122 citations

Metabolic effects of altering the 24 h energy intake in man, using direct and indirect calorimetry

1980 • 121 citations

Metabolic relationships between lipolysis and respiration in rat brown adipocytes. The role of long chain fatty acids as regulators of mitochondrial respiration and feedback inhibitors of lipolysis.

1981 • 118 citations

Hypothalamic regulation of lipid metabolism in the rat: Effect of hypothalamic stimulation on lipolysis

1981 • 108 citations

Calorigenic response in obese and nonobese women

1976 • 104 citations

Thermoregulation in the diabetic-obese (db/db) mouse

1979 • 104 citations

Effect of chronic food restriction on energy balance, thermogenic capacity, and brown-adipose-tissue activity in the rat

1982 • 98 citations

Role of thyroid hormone in cold-induced changes in rat brown adipose tissue mitochondria

1982 • 95 citations

Effects of Feeding a “Cafeteria” Diet on Energy Balance and Diet-Induced Thermogenesis in Four Strains of Rat

1982 • 94 citations

Abnormal sympatho-adrenal function and plasma catecholamines in obese Zucker rats

1980 • 93 citations

Nutritional Factors: Modulating Effects on Metabolic Processes.

1983 • 92 citations

An Assessment of Human Regulatory Nonshivering Thermogenesis

1980 • 91 citations

The Acute Regulation of Mitochondrial Proton Conductance in Cells and Mitochondria from the Brown Fat of Cold‐Adapted and Warm‐Adapted Guinea Pigs

1982 • 84 citations

Spontaneous sweat secretion in calcium-free strontium medium

1982 • 84 citations

Maintenance Requirement and Energetic Efficiency of Lean and Obese Zucker Rats

1976 • 82 citations

Energy expenditure of ‘cafeteria’‐fed rats determined from measurements of energy balance and indirect calorimetry.

1982 • 80 citations

GDP binding to brown-adipose-tissue mitochondria of diabetic-obese (db/db) mice. Decreased binding in both the obese and pre-obese states

1981 • 80 citations

Metabolic effects of a mixed and a high-carbohydrate low-fat diet in man, measured over 24 h in a respiration chamber

1982 • 70 citations

Comparison of microspheres and ⁸⁶Rb⁺ as tracers of the distribution of cardiac output in rats indicates invalidity of ⁸⁶Rb⁺-based measurements

1978 • 69 citations

Acute effects of food, 2-deoxy-d-glucose and noradrenaline on metabolic rate and brown adipose tissue in normal and atropinised lean and obese (fa/fa) Zucker rats

1981 • 67 citations

Nutritional Effects on Thyroid and Catecholamine Metabolism

1980 • 62 citations

Increased thermal body insulation: relationship to the development of obesity.

1974 • 62 citations

EFFECTS OF HYPOTHYROIDISM ON THE BROWN ADIPOSE TISSUE OF ADULT RATS: COMPARISON WITH THE EFFECTS OF ADAPTATION TO COLD

1981 • 61 citations

Obesity and Metabolism

2008 • 60 citations

Studies on the activity of brown adipose tissue in suckling, pre-obese, obob mice

1982 • 60 citations

Impaired metabolic response to nerve stimulation in brown adipose tissue of hypothyroid rats

1982 • 59 citations

EFFECTS OF DIET AND ACUTE NORADRENALINE TREATMENT ON BROWN ADIPOSE TISSUE DEVELOPMENT AND MITOCHONDRIAL PURINE‐NUCLEOTIDE BINDING

1982 • 57 citations

Thyroid Hormones and Thermogenesis

1983 • 55 citations

Handbook of the hypothalamus, vol. 2. Physiology of the hypothalamus

1981 • 52 citations

Energy Balances in Obese Mice

1979 • 51 citations

Parallel regression of cold-induced changes in ultrastructure, composition, and properties of brown adipose tissue mitochondria during recovery of rats from acclimation to cold

1980 • 49 citations

Alterations of Brown Adipose Tissue in Genetically Obese (ob/ob) Mice. I. Demonstration of Loss of Metabolic Response to Nerve Stimulation and Catecholamines and Its Partial Recovery after Fasting or Cold Adaptation*

1982 • 46 citations

Factors influencing the acute effect of food on oxygen consumption in the rat.

1982 • 45 citations

Defective catecholamine metabolism in peripheral organs of genetically obese zucker rats

1981 • 44 citations

Initiation, duration and dissipation of diet-induced changes in sympathetic nervous system activity in the rat

1982 • 42 citations

Regional blood flow in genetically--obese rats during nonshivering thermogenesis.

1982 • 39 citations

The development of obesity in genetically diabetic-obese (db/db) mice pair-fed with lean siblings

1980 • 38 citations

Plasma catecholamines and autonomic responsiveness in obesity.

1982 • 32 citations

Dietary-induced thermogenesis: Control of energy expenditure

1981 • 30 citations

Hypothalamic regulation of lipid metabolism in the rat: effect of hypothalamic stimulation on lipogenesis

1982 • 27 citations

Metabolic and sympatho-adrenal abnormalities in the obese zucker rat: Effect of chronic phenoxybenzamine treatment

1981 • 27 citations

Neural regulation of thermogenesis

1982 • 25 citations

Effects of exercise in cool water on body weight loss.

1982 • 24 citations

Isoproterenol alters nonshivering thermogenesis in the Zucker obese rat (fafa)

1982 • 19 citations

A comparison of the relative binding energies of H⁺ and NO⁺ to aromatic and haloaromatic bases by high pressure mass spectrometry

1982 • 7 citations

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