Pharmacokinetics and pharmacodynamics of isosorbide dinitrate

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Oral Isosorbide dinitrate in angina pectoris: Comparison of duration of action and dose-response relation during acute and sustained therapy

1982 • 303 citations

Organic nitrates: relationship between biotransformation and rational angina pectoris therapy.

1972 • 220 citations

Transdermal isosorbide dinitrate in angina pectoris: Effect of acute and sustained therapy

1984 • 129 citations

Oral isosorbide dinitrate in the treatment of angina pectoris. Dose-response relationship and duration of action during acute therapy.

1980 • 111 citations

GLC Determination of Nitroglycerin and Isosorbide Dinitrate in Human Plasma

1973 • 99 citations

Systemic and coronary vascular effects of the 2- and the 5-mononitrate esters of isosorbide.

1972 • 72 citations

Improved GLC Determination of Plasma Nitroglycerin Concentrations

1978 • 66 citations

Kinetics of isosorbide dinitrate and relationships to pharmacological effects.

1981 • 62 citations

Pharmacokinetic determinants of nitrate action

1984 • 51 citations

Pharmacokinetics of nitroglycerin and long-acting nitrate esters

1983 • 47 citations

Isosorbide dinitrate kinetics and dynamics after intravenous, sublingual, and percutaneous dosing in angina

1983 • 45 citations

Measurement of plasma concentrations of isosorbide dinitrate

1980 • 35 citations

Isosorbide dinitrate pharmacokinetics.

1982 • 23 citations

Hepatic extraction of isosorbide dinitrate in cardiac patients

1983 • 21 citations

Metabolites decrease the plasma clearance of isosorbide dinitrate in rats

1984 • 17 citations

Determination of the partitioning, stability, and metabolite formation of isosorbide dinitrate in human and rat blood using an improved gas-liquid chromatographic assay

1984 • 16 citations

Isosorbide dinitrate disposition in the rat: metabolite pharmacokinetics and interactions.

1984 • 16 citations

Prolonged plasma half-life after oral isosorbide dinitrate in patients with angina pectoris.

1983 • 13 citations

[Pharmacokinetics of isosorbide dinitrate administered by intravenous infusion to hypertensive patients (author's transl)].

1982 • 6 citations