Role of Autophagy in Cancer: Management of Metabolic Stress

The Hallmarks of Cancer

2000 • 27,569 citations

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

2015 • 15,801 citations

Cell Death

2004 • 4,599 citations

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

2006 • 3,685 citations

Development by Self-Digestion

2004 • 3,562 citations

Loss of autophagy in the central nervous system causes neurodegeneration in mice

2006 • 3,331 citations

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1999 • 3,194 citations

On Respiratory Impairment in Cancer Cells

1956 • 2,963 citations

The role of autophagy during the early neonatal starvation period

2004 • 2,753 citations

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

2005 • 2,207 citations

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

2003 • 2,136 citations

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

2003 • 2,041 citations

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

2006 • 1,920 citations

Smoldering and polarized inflammation in the initiation and promotion of malignant disease

2005 • 1,730 citations

Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis

2005 • 1,448 citations

The Bcl-2 family: roles in cell survival and oncogenesis

2003 • 1,448 citations

The pleiotropic role of autophagy: from protein metabolism to bactericide

2005 • 465 citations

Angiogenesis and apoptosis

2003 • 419 citations

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy

2005 • 286 citations

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

2004 • 266 citations

Autophagy, Mitochondrial Quality Control, and Oncogenesis

2006 • 162 citations

Addicted to Death

2004 • 157 citations

BAX and BAK mediate p53-independent suppression of tumorigenesis

2002 • 135 citations

Accumulation of ubiquitin-conjugated cytokeratin fragments in tumor cells

2005 • 10 citations