Factors affecting the time course of decay of end‐plate currents: a possible cooperative action of acetylcholine on receptors at the frog neuromuscular junction.

Quantal components of the end‐plate potential

1954 • 2,182 citations

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

1957 • 1,457 citations

An analysis of the end‐plate potential recorded with an intra‐cellular electrode

1951 • 1,389 citations

Voltage clamp analysis of acetylcholine produced end‐plate current fluctuations at frog neuromuscular junction

1973 • 992 citations

The statistical nature of the acetylcholine potential and its molecular components

1972 • 960 citations

A quantitative description of end‐plate currents

1972 • 625 citations

The nature of the neuromuscular block produced by magnesium

1954 • 619 citations

Statistical factors involved in neuromuscular facilitation and depression

1954 • 582 citations

The binding of acetylcholine to receptors and its removal from the synaptic cleft

1973 • 576 citations

Acetylcholine Receptors in Muscle Fibres

1971 • 443 citations

The effect of voltage on the time course of end‐plate currents

1972 • 443 citations

On the application of “a plausible model” of allosteric proteins to the receptor for acetylcholine

1967 • 425 citations

Isolation of neurotoxins from the venom of Bungarus multicinctus and their modes of neuromuscular blocking action

1965 • 379 citations

ACTIVE PHASE OF FROG'S END-PLATE POTENTIAL

1959 • 348 citations

Inward and delayed outward membrane currents in isolated neural somata under voltage clamp

1971 • 332 citations

The nature of the antagonism between calcium and magnesium ions at the neuromuscular junction

1957 • 330 citations

An analysis of facilitation of transmitter release at the neuromuscular junction of the frog

1967 • 302 citations

Isolation of the Principal Neurotoxins of Two Naja naja Subspecies

1971 • 248 citations

On the mechanism of desensitization at cholinergic receptors.

1970 • 247 citations

Enzymatic Detachment of Endplate Acetylcholinesterase from Muscle

1971 • 245 citations

The antagonism between tubocurarine and substances which depolarize the motor end‐plate

1960 • 235 citations

The relationship between the mode of operation and the dimensions of the junctional regions at synapses and motor end-organs

1958 • 233 citations

Localization of active spots within the neuromuscular junction of the frog

1956 • 232 citations

The electromotive action of acetylcholine at the motor end‐plate

1950 • 212 citations

Effects of proteolytic enzymes on function and structure of frog neuromuscular junctions

1973 • 209 citations

Repetitive stimulation at the mammalian neuromuscular junction, and the mobilization of transmitter

1963 • 208 citations

EFFECT OF ESERINE ON NEUROMUSCULAR TRANSMISSION

1942 • 171 citations

PRESYNAPTIC NATURE OF NEUROMUSCULAR DEPRESSION

1962 • 161 citations

On the excitability and cooperativity of the electroplax membrane.

1968 • 159 citations

Binding of Naja nigricollis (3H)alpha-toxin to membrane fragments from Electrophorus and Torpedo electric organs. II. Effect of cholinergic agonists and antagonists on the binding of the tritiated alpha-neurotoxin.

1974 • 148 citations

Alteration by Xylocaine (Lidocaine) and Its Derivatives of the Time Course of the End Plate Potential

1968 • 143 citations

A lesion of the transverse tubules of skeletal muscle

1969 • 139 citations

Action Potentials without Contraction in Frog Skeletal Muscle Fibers with Disrupted Transverse Tubules

1967 • 131 citations

Drug Receptors and their Function

1971 • 125 citations

Apparent dissociation constants between carbamylcholine, d-tubocurarine and the receptor

1963 • 121 citations

Motor end‐plate ‘desensitization’ by repetitive nerve stimuli

1959 • 118 citations

ACTIONS OF ANTI-CHOLINESTERASES ON ENDPLATE POTENTIAL OF FROG MUSCLE

1949 • 101 citations

A Kinetic Model for the Action of Xylocaine on Receptors for Acetylcholine

1968 • 96 citations

“Disjunction” of Frog Neuromuscular Synapses by Treatment with Proteolytic Enzymes

1971 • 95 citations

ELECTROPHYSIOLOGICAL STUDY OF NEUROMUSCULAR BLOCKING ACTION OF COBRA NEUROTOXIN*

1966 • 90 citations

Further Observations on Acetylcholine Noise

1971 • 89 citations

The effect of tetanic and post‐tetanic potentiation on facilitation of transmitter release at the frog neuromuscular junction

1973 • 84 citations

Binding of acetylcholine and related compounds to purified acetylcholine receptor from Torpedocalifornica electroplax

1973 • 68 citations

A comparison of acetylcholine and stable depolarizing agents

1957 • 67 citations

The effect of atropine on the frog sartorius neuromuscular junction

1968 • 67 citations

Studies on the nature of the cholinergic receptor

1968 • 63 citations

THE EFFECT OF ACETYLCHOLINE ON NEUROMUSCULAR TRANSMISSION IN THE FROG.

1963 • 58 citations

The effect of atropine on acetylcholine action at the neuromuscular junction

1973 • 55 citations

Diisopropylfluorophosphate: Suppression of Ionic Conductance of the Cholinergic Receptor

1973 • 54 citations

Influence of chloride ions on changes in membrane potential during prolonged application of carbachol to frog skeletal muscle

1973 • 43 citations

Cooperativities in the binding of acetylcholine to its receptor

1973 • 36 citations

The effect of α‐bungarotoxin on acetylcholine receptors

1973 • 35 citations

Effect of prostigmine on the time course of the end‐plate potential in the rat diaphragm

1971 • 33 citations

Blockade of acetylcholine receptors by cobra toxin: electrophysiological studies.

1972 • 31 citations

Vulnerability of desensitized or curare-treated acetylcholine receptors to irreversible blockade by cobra toxin.

1972 • 29 citations

The interaction of tensilon and neostigmine with acetylcholinesterase.

1955 • 21 citations

A new model for transmitter mobilization in the frog neuromuscular junction

1973 • 15 citations

Inactivation of cholinesterase by compounds related to neostigmine.

1955 • 8 citations

Estimation of the dissociation constant of d-tubocurarine and the receptor for endogenous acetylcholine.

1972 • 5 citations