Cyclic AMP metabolism in rat liver during 2-acetylaminofluorene carcinogenesis

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Advances in Cyclic Nucleotide Research.

1980 • 1,465 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

Studies on the Mechanism of Hormone Action

1972 • 682 citations

Specific determination of blood glucose with o-toluidine

1962 • 561 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 519 citations

Cyclic AMP levels in fibroblasts: Relationship to growth rate and contact inhibition of growth

1971 • 443 citations

Morphologic Differentiation of Mouse Neuroblastoma Cells induced in vitro by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 383 citations

Rapid Specific Method for Determination of Aldosaccharides in Body Fluids

1959 • 380 citations

Regulation of Cell Growth by Cyclic Adenosine 3′,5′-Monophosphate

1972 • 314 citations

Expression of Differentiated Functions in Mouse Neuroblastoma mediated by Dibutyryl-cyclic Adenosine Monophosphate

1971 • 261 citations

Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro

1968 • 261 citations

Inhibition of Cell Growth in vitro by Adenosine 3′,5′-Monophosphate

1968 • 251 citations

Simple Method for the Determination of Plasma Corticoids

1963 • 234 citations

Reduced Adenyl Cyclase Activity in a Polyoma Virus Transformed Cell Line

1968 • 214 citations

Enzymic Differentiation in Mammalian Liver

1969 • 213 citations

THE ROLE OF ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE IN THE REGULATION OF MAMMALIAN CELL DIVISION

1973 • 209 citations

Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism.

1967 • 202 citations

Evidence for a Primary Association between Immunoblasts and Small Gut

1972 • 197 citations

Organizational difference of cell surface “hematoside” in normal and virally transformed cells

1968 • 191 citations

Carbohydrate-containing membrane components of normal and virus-transformed mouse fibroblasts. I. Glucosamine-labeling patterns in 3T3, spontaneously transformed 3T3, and SV-40-transformed 3T3 cells

1969 • 180 citations

Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver

1970 • 174 citations

Increases in rat liver cyclic AMP concentrations prior to the initiation of DNA synthesis following partial hepatectomy or hormone infusion

1972 • 160 citations

Calcium, cyclic adenosine 3′, 5′-monophosphate, and the control of cell proliferation: A review

1973 • 154 citations

EFFECT OF ADENOSINE 3'-5'-CYCLIC MONOPHOSPHATE ON CELL PROLIFERATION

1972 • 151 citations

Adrenergic antagonists, and a possible link between the increase in cyclic adenosine 3′,5′‐monophosphate and DNA synthesis during liver regeneration

1973 • 145 citations

The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent.

1955 • 135 citations

Stimulation of DNA synthesis and mitotic activity of thymic lymphocytes by cyclic adenosine 3′5′-monophosphate

1969 • 132 citations

A Mutation in a Rous Sarcoma Virus Gene That Controls Adenosine 3′,5′-Monophosphate Levels and Transformation

1972 • 130 citations

Independent Variation of Glucagon and Epinephrine Responsive Components of Hepatic Adenyl Cyclase as a Function of Age, Sex and Steroid Hormones

1970 • 119 citations

Control of DNA synthesis and mitosis in 3T3 cells by cyclic AMP

1972 • 117 citations

Evidence for a β-adrenergic receptor initiating DNA synthesis in haemopoietic stem cells

1972 • 111 citations

Role of 3′,5′ -Adenosine Monophosphate in Regulation of Morphology and Growth of Transformed and Normal Fibroblasts

1972 • 109 citations

Quantitative aspects of the reaction of some carcinogens with nucleic acids and the possible significance of such reactions in the process of carcinogenesis.

1966 • 106 citations

Morphometric analysis of the rat liver cell in the perinatal period.

1971 • 103 citations

A critical review of experiments in chemical carcinogensis using newborn animals.

1968 • 101 citations

Developmental changes in cyclic AMP, protein kinase, phosphorylase kinase, and phosphorylase in liver, heart, and skeletal muscle of the rat

1972 • 99 citations

Evidence for separate epinephrine and glucagon responsive adenyl cyclase systems in rat liver

1968 • 98 citations

Biochemistry of carcinogenesis.

1968 • 93 citations

The role of cyclic nucleotides in carcinogenesis

1973 • 85 citations

Development of cyclic AMP metabolism in rat liver a correlative study of tissue levels of cyclic AMP, accumulation of cyclic AMP in slices, adenylate cyclase activity and cyclic nucleotide phosphodiesterase activity

1973 • 84 citations

Effects of derivatives of cyclic 3',5'-adenosine monophosphate on the growth, morphology, and gene expression of hepatoma cells in culture.

1972 • 81 citations

Adenylate‐Cyclase Activity of Rat‐Liver Plasma Membranes

1973 • 76 citations

Tissue Regeneration and Tumour Development

1959 • 73 citations

The effect of starvation on tissue adenosine 3′–5′ monophosphate levels

1973 • 61 citations

Adenyl cyclase: Relationship to stimulated DNA synthesis in parotid glands

1969 • 61 citations

Cyclic AMP in cultured human lymphoid cells: Relationship to mitosis

1972 • 60 citations

Cyclic 3′:5′ AMP and cell proliferation in cultures of embryonic rat cells

1972 • 59 citations

Selective Effects of Cholera Toxin on the Adrenaline Responsive Component of Hepatic Adenyl Cyclase

1972 • 54 citations

Development of Rat Liver Adenylcyclase

1971 • 51 citations

Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate in cultured hepatoma cells.

1973 • 51 citations

Hepatic adenyl cyclase: Alterations in hormone response during treatment with a chemical carcinogen

1972 • 50 citations

Control of the adenosine 3',5'-monophosphate-adenyl cyclase system in the livers of developing rats.

1972 • 49 citations

Protein kinase: Altered regulation in a hepatoma cell line deficient in adenosine 3′, 5′-cyclic monophosphate-binding protein

1972 • 49 citations

Glucagon and prostaglandin E1 stimulation of cyclic adenosine 3', 5'-monophosphate levels and adenylate cyclase activity in benign hyperplastic nodules and malignant hepatomas of ethionine-treated rats.

1973 • 44 citations

Glucagon control of cyclic AMP accumulation in isolated intact rat liver parenchymal cells in vitro

1974 • 44 citations

Quiescent SV40 virus transformed 3T3 cells in culture

1973 • 43 citations

Cellular Analysis of Liver Carcinogenesis. III. Comparison of the Ultrastructure of Hyperplastic Liver Nodules and Hepatocellular Carcinomas Induced in Rat Liver by 2-Fluorenylacetamide<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1969 • 41 citations

Binding of chemical carcinogens to nuclear proteins of rat liver.

1972 • 39 citations

Cyclic 3′,5′‐adenosine monophosphate‐mediated follicular reorganization of isolated thyroid cells in culture

1970 • 38 citations

Protein kinase activity in morris hepatomas

1973 • 37 citations

Selective Effects of Insulin on Hepatic Epinephrine Responsive Adenyl Cyclase Activity

1972 • 35 citations

Birth of the Open University

1971 • 33 citations

Type C Virus from Cell Cultures of Chemically Induced Rat Hepatomas

1972 • 31 citations

Chemical carcinogens and RNA.

1971 • 29 citations

Cell Proliferation in Precancerous Liver: Relation to Presence and Dose of Carcinogen<xref ref-type="fn" rid="FN1">2</xref>

1961 • 27 citations

Reversible inhibition of cell multiplication by a small class of liver proteins

1966 • 24 citations

Paper chromatography combined with phosphodiesterase treatment in the determination of radioactively labelled cyclic 3′,5′-adenosine monophosphate

1972 • 22 citations

Enrichment of glucagon sensitive adenyl cyclase upon preparation of parenchymal cells from rat liver

1972 • 21 citations

Glucagon and Epinephrine Activation of Adenylate Cyclase and Clucagon Binding in Morris Hepatomas*

1974 • 19 citations

Adenyl cyclase in hepatic parenchymal and reticuloendothelial cells

1971 • 18 citations

Irreversibility of the alteration in RNA transport induced by an AZO-DYE carcinogen in the rat liver

1974 • 15 citations

Glucagon Stimulation of DNA Synthesis in Neonatal‐Rat Liver

1973 • 5 citations

PLASMA CORTICOSTEROID RESPONSE TO METYRAPONE

1973 • 4 citations