Nature and mode of action of vaccinia virus products that block activation of the interferon-mediated ppp(A2′p)nA-synthetase

The Interferon System

1979 • 1,035 citations

Biochemistry of Interferons and Their Actions

1982 • 868 citations

pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

1978 • 787 citations

Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts

1978 • 435 citations

Interferon action may be mediated by activation of a nuclease by pppA2′p5′A2′p5′A

1978 • 310 citations

Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)_nA) in interferon-treated cells

1981 • 245 citations

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1980 • 242 citations

Double-stranded RNA in Vaccinia Virus Infected Cells

1969 • 191 citations

An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.

1979 • 183 citations

Interferon action: Isolation of Nuclease F, A translation inhibitor activated by interferon‐induced (2′–5′) oligo‐isoadenylate

1978 • 167 citations

Mechanism for discrimination between viral and host mRNA in interferon-treated cells.

1979 • 163 citations

Biology of Poxviruses

1981 • 138 citations

Two Nucleic Acid-dependent Nucleoside Triphosphate Phosphohydrolases from Vaccinia Virus

1974 • 134 citations

Polynucleotide. CXXIV. Reversal of bacteriophage T₄ induced polynucleotide kinase action

1973 • 134 citations

Interferon, double-stranded RNA and RNA degradation. Fractionation of the endonucleaseINT system into two macromolecular components; Role of a small molecule in nuclease activation

1978 • 131 citations

Effect of salts and polyamines on T₄ polynucleotide kinase

1975 • 123 citations

Control of the ppp(A2′p)_nA System in HeLa Cells

1982 • 115 citations

Resistance of vaccinia virus to interferon is related to an interference phenomenon between the virus and the interferon system

1984 • 113 citations

Metabolic stability of 2′ 5′oligo (A) and activity of 2′ 5′oligo (A)-dependent endonuclease in extracts of interferon-treated and control HeLa cells

1979 • 103 citations

Two Nucleic Acid-dependent Nucleoside Triphosphate Phosphohydrolases from Vaccinia Virus

1974 • 96 citations

Intermolecular duplexes formed from polyadenylylated vaccinia virus RNA

1979 • 86 citations

Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells.

1980 • 86 citations

Kinetics and specificity of T₄ polynucleotide kinase

1975 • 79 citations

Reproduction of Poxviruses

1974 • 76 citations

Inhibition of protein synthesis by vaccinia virus

1981 • 36 citations

[27] Analysis of (2′-5′)-oligo(A) and related oligonucleotides by high-performance liquid chromatography

1981 • 33 citations

Induction of an antiviral response by interferon requires thymidine kinase.

1983 • 30 citations

Transcription of both DNA strands of vaccinia virus genome in vivo

1979 • 23 citations

[26] Assay of (2′-5′)-oligo(A) synthesized in Vitro and the analysis of naturally occurring (2′-5′)-oligo(A) from intact cells

1981 • 14 citations