Quantification of radiation-induced regional lung injury with perfusion imaging

Tolerance of normal tissue to therapeutic irradiation

1991 • 4,329 citations

A Method for Attenuation Correction in Radionuclide Computed Tomography

1978 • 1,273 citations

Complication Probability as Assessed from Dose-Volume Histograms

1985 • 1,133 citations

Pulmonary Effects of Radiation Therapy

1977 • 575 citations

Radiation pneumonitis in breast cancer patients treated with conservative surgery and radiation therapy

1991 • 412 citations

Mantle irradiation in Hodgkin's disease.An analysis of technique, tumor eradication, and complications

1976 • 390 citations

Long-term results of combined chemotherapy-radiotherapy approach in Hodgkin's disease: superiority of ABVD plus radiotherapy versus MOPP plus radiotherapy.

1987 • 384 citations

Optimization of radiation therapy, III: A method of assessing complication probabilities from dose-volume histograms

1987 • 377 citations

Transforming Growth Factor β as a Predictor of Liver and Lung Fibrosis after Autologous Bone Marrow Transplantation for Advanced Breast Cancer

1993 • 318 citations

Dose-volume histogram and 3-D treatment planning evaluation of patients with pneumonitis

1994 • 278 citations

Radiation pneumonitis following large single dose irradiation: A re-evaluation based on absolute dose to lung

1981 • 274 citations

Modification of radiation injury to normal tissues by chemotherapeutic agents

1975 • 273 citations

Clinical value of quantitative ventilation-perfusion lung scans in the surgical management of bronchogenic carcinoma

1980 • 219 citations

Acute radiation-induced pulmonary damage: A clinical study on the response to fractionated radiation therapy

1987 • 194 citations

Radiation pneumonitis: Experience following a large single dose of radiation

1978 • 179 citations

Radiation Pneumonitis and Fibrosis in Mouse Lung Assayed by Respiratory Frequency and Histology

1980 • 172 citations

Late cardiac, thyroid, and pulmonary sequelae of mantle radiotherapy for hodgkin's disease

1985 • 168 citations

Changes in plasma TGFβ levels during pulmonary radiotherapy as a predictor of the risk of developing radiation pneumonitis

1994 • 147 citations

The utility of SPECT lung perfusion scans in minimizing and assessing the physiologic consequences of thoracic irradiation

1993 • 143 citations

Thoracic irradiation in hodgkin's disease: disease control and long-term complications

1990 • 142 citations

Prediction of Pulmonary Function Loss Due to Pneumonectomy Using 133Xe-Radiospirometry

1972 • 141 citations

Radiation-induced lung damage: dose-time-fractionation considerations

1989 • 133 citations

Optimization of 3d radiation therapy with both physical and biological end points and constraints

1992 • 123 citations

Radiation pneumonitis in patients treated for breast cancer

1985 • 121 citations

The role of three dimensional functional lung imaging in radiation treatment planning: The functional dose-volume histogram

1995 • 114 citations

Pediatric hodgkin's disease: pulmonary, cardiac, and thyroid function following combined modality therapy

1989 • 113 citations

Post-mastectomy radiotherapy following adjuvant chemotherapy and autologous bone marrow transplantation for breast cancer patients with ≥ 10 positive axillary lymph nodes

1992 • 109 citations

Long-term toxicity of early stages of Hodgkin's disease therapy: The EORTC experience

1991 • 109 citations

Estimation of overall pulmonary function after irradiation using dose-effect relations for local functional injury

1995 • 105 citations

Damage and morbidity from pneumonitis after irradiation of partial volumes of mouse lung

1995 • 99 citations

Pulmonary toxicity after radiation and bleomycin: A review

1979 • 86 citations

The role of radiotherapy in the management of malignant thymoma

1972 • 86 citations

Prediction of postoperative pulmonary function following thoracic operations. Value of ventilation-perfusion scanning.

1983 • 86 citations

Dose-effect relations for local functional and structural changes of the lung after irradiation for malignant lymphoma

1994 • 86 citations

Effect of cancer chemotherapeutic drugs on radiation-induced lung damage in mice

1986 • 81 citations

Results of a prospective study evaluating the effects of mantle irradiation on pulmonary function

1989 • 76 citations

A new method to determine dose-effect relations for local lung-function changes using correlated SPECT and CT data

1993 • 75 citations

The Effects of Radiation Therapy on Pulmonary Function in Carcinoma of the Lung

1965 • 75 citations

Lung cancer in patients with borderline lung functions - zonal lung perfusion scans at presentation and lung function after high dose irradiation

1990 • 74 citations

Prospective study of long-term pulmonary manifestations of mantle irradiation

1990 • 73 citations

Prospective prediction of post-radiation therapy lung function using quantitative lung scans and pulmonary function testing

1988 • 73 citations

The Kinetics of Repair in Mouse Lung after Fractionated Irradiation

1987 • 72 citations

Quantitative effect of combined chemotherapy and fractionated radiotherapy on the incidence of radiation-induced lung damage: A prospective clinical study

1994 • 71 citations

Effects of smoking and irradiated volume on inflammatory response in the lung of irradiated breast cancer patients evaluated with bronchoalveolar lavage.

1990 • 71 citations

Multifraction Radiation Response of Mouse Lung

1985 • 71 citations

Diagnostic imaging of post-irradiation changes in the chest

1988 • 69 citations

Prediction of postoperative pulmonary function following thoracic operations

1983 • 68 citations

Quantitative measurement of changes in human lung density following irradiation

1988 • 67 citations

Iso-effect tables for tolerance of irradiated normal human tissues

1983 • 65 citations

Influence of radiation therapy on the lung-tissue in breast cancer patients: CT-assessed density changes and associated symptoms

1990 • 65 citations

Minimal long-term cardiopulmonary dysfunction following treatment for Hodgkin's disease

1987 • 64 citations

Observations on the predictive value of perfusion lung scans on post-irradiation pulmonary function among 210 patients with bronchogenic carcinoma

1992 • 63 citations

The pathophysiologic and roentgenologic effects of chest irradiation in breast carcinoma

1986 • 61 citations

Physiological and Radiographic Assessment During the Development of Pulmonary Radiation Fibrosis

1977 • 59 citations

Effect of postoperative radiotherapy on changes in pulmonary function in patients with stage II and IIIA lung carcinoma

1990 • 51 citations

An analysis of 40 cases treated by total thoracic irradiation

1969 • 46 citations

Late functional, biochemical and histological changes in the rat lung after fractionated irradiation to the whole thorax

1987 • 32 citations

Early and late effects of fractionated irradiation and the kinetics of repair in rat lung

1990 • 32 citations

Pulmonary toxicity of a combination of low-dose doxorubicin and irradiation for inoperable lung cancer

1987 • 29 citations

The Effect of Thoracic Irradiation for Cancer of the Breast on Ventilation, Perfusion and Pulmonary Permeability: A one-Year Follow-Up

1989 • 29 citations

Response of the canine lung to fractionated irradiation: pathologic changes and isoeffect curves

1989 • 26 citations

Diagnostic imaging of post-irradiation changes in the chest

1988 • 25 citations

Serum markers for prediction of pulmonary radiation syndromes. Part I: Surfactant apoprotein

1989 • 23 citations

SPECT Quantification of Technetium-99m Microspheres Within the Canine Lung

1985 • 19 citations

Estimation of normal tissue complication probabilities with three-dimensional technology

1994 • 18 citations

Positioning and Immobilization of Patients Undergoing Radiation Therapy for Hodgkin’s Disease

1991 • 17 citations

In vivo regional quantitation of intrathoracic Tc-99m using SPECT: concise communication.

1982 • 16 citations

Dissociation of early and late damage in mouse lung

1980 • 10 citations

Computerized tomography versus perfusion lung scanning in canine radiation lung injury

1990 • 9 citations

Heterogeneous ventilation and perfusion: a sensitive indicator of lung impairment in nonsmoking coal miners

1988 • 9 citations

Local dose-effect relations for pulmonary perfusion and ventilation changes and overall lung function loss after radiotherapy

1994 • 5 citations