Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

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1983 • 1,118 citations

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1980 • 572 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

1986 • 320 citations

A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast

1983 • 288 citations

Integration of amino acid biosynthesis into the cell cycle of Saccharomyces cerevisiae

1975 • 252 citations

The nucleotide sequence of the HIS4 region of yeast

1982 • 233 citations

CONTROL OF ISOLEUCINE, VALINE, AND LEUCINE BIOSYNTHESIS, I. MULTI-VALENT REPRESSION

1962 • 198 citations

Permeabilization of microorganisms by Triton X-100

1978 • 189 citations

Tryptophan biosynthesis in Saccharomyces cerevisiae: control of the flux through the pathway

1978 • 189 citations

Regulatory sites for his3 gene expression in yeast

1982 • 165 citations

Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product.

1984 • 152 citations

Transcription of the his3 gene region in Saccharomyces cerevisiae

1981 • 145 citations

A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene (CYC1) of yeast.

1985 • 144 citations

Nucleotide sequence of the yeastILV2gene which encodes acetolactate synthase

1985 • 144 citations

The Regulation of Arginine Biosynthesis in Saccharomyces cerevisiae. The Specificity of argR- Mutations and the General Control of Amino-Acid Biosynthesis

1975 • 141 citations

GENE CONVERSION OF DELETIONS IN THE HIS4 REGION OF YEAST

1974 • 128 citations

Subcellular Localization of Isoleucine-Valine Biosynthetic Enzymes in Yeast

1974 • 120 citations

Biological role of the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

1981 • 119 citations

The General Control of Amino Acid Biosynthetic Genes in the Yeast Saccharomyces Cerevisia

1986 • 112 citations

Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts.

1986 • 89 citations

The Regulation of Isoleucine‐Valine Biosynthesis in Saccharomyces cerevisiae

1968 • 87 citations

Leucine biosynthesis in yeast

1983 • 83 citations

Role of an upstream regulatory element in leucine repression of the Saccharomyces cerevisiae leu2 gene

1984 • 75 citations

Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2.

1984 • 74 citations

TheILVSgene ofSaccharomyces cerevisiaeis highly expressed

1986 • 72 citations

Regulation of HIS4-lacZ Fusions in Saccharomyces cerevisiae

1982 • 69 citations

Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Leucine Biosynthesis in Prototrophic and Leucine Auxotrophic Strains

1968 • 65 citations

GENETIC AND BIOCHEMICAL ANALYSIS OF ISOLEUCINE-VALINE MUTANTS OF YEAST

1964 • 58 citations

Identification and characterization of four new GCD genes in Saccharomyces cerevisiae

1986 • 45 citations

Biosynthesis of branched-chain amino acids in yeast: effect of carbon source on leucine biosynthetic enzymes

1975 • 44 citations

Biosynthesis of Branched-Chain Amino Acids in Yeast: Regulation of Synthesis of the Enzymes of Isoleucine and Valine Biosynthesis

1969 • 43 citations

Multivalent Repression of Isoleucine-Valine Biosynthesis in Saccharomyces cerevisiae

1969 • 42 citations

Biological Role of the General Control of Amino Acid Biosynthesis in Saccharomyces cerevisiae

1981 • 41 citations

Action of tryptophan analogues in Saccharomyces cerevisiae

1977 • 37 citations

Nucleotide sequence of the gene for threonine deaminase (ILV1) of Saccharomyces cerevisiae

1984 • 35 citations

Regulation of HIS4-lacZ fusions in Saccharomyces cerevisiae.

1982 • 35 citations

Involvement of Threonine Deaminase in Multivalent Repression of the Isoleucine-Valine Pathway in Saccharomyces cerevisiae

1971 • 31 citations

Involvement of Threonine Deaminase in Repression of the Isoleucine-Valine and Leucine Pathways in Saccharomyces cerevisiae

1973 • 28 citations

Molecular cloning and characterization of the threonine deaminase (ILV1) gene of Saccharomyces cerevisiae

1983 • 28 citations

Cloning of theILV2, ILV3 andILV5 genes of Saccharomyces cerevisiae

1984 • 24 citations

Molecular characterization of a Saccharomyces plasmid containing theHIS4 gene

1979 • 23 citations

Fine structure analysis of a eukaryotic multifunctional gene

1974 • 19 citations

Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae

1975 • 18 citations

[111] Branched-chain amino acid aminotransferase (pig heart mitochondria)

1970 • 15 citations

TheILV1 gene in Saccharomyces cerevisiae: 5′ and 3′ end mapping of transcripts and their regulation

1985 • 10 citations

The action of O‐methyl‐threonine and thiaisoleucine on threonine deaminase purified fromEscherichia coli K‐12

1972 • 9 citations