Structure-Based Design, Synthesis, and X-ray Crystallography of a High-Affinity Antagonist of the Grb2-SH2 Domain Containing an Asparagine Mimetic

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

1990 • 3,683 citations

Semianalytical treatment of solvation for molecular mechanics and dynamics

1990 • 3,585 citations

Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

1987 • 849 citations

Solid Phase Peptide Synthesis — A Practical Approach

1990 • 680 citations

Surface concentrations and residence times of intermediates on samarium oxide during the oxidative coupling of methane

1990 • 281 citations

The FROG PC series: programs for electron-density and model investigations for proteins

1993 • 213 citations

The GRB2/Sem‐5 adaptor protein

1994 • 182 citations

Annual Reports in Medicinal Chemistry, 1965.

1967 • 154 citations

Near-coincidence orientations in hexagonal materials: from a unified twin approach to a quasiperiodic description

1991 • 146 citations

The Grb2 adaptor

1995 • 127 citations

Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases

1993 • 101 citations

SH2 and SH3 domains: Potential targets for anti-cancer drug design

1995 • 95 citations

Structure-Based Design and Synthesis of High Affinity Tripeptide Ligands of the Grb2-SH2 Domain

1998 • 82 citations

Reduction of N-chlorosulfonyl-.beta.-lactams to .beta.-lactams with sodium sulfite

1970 • 74 citations

Discovery of 3-Aminobenzyloxycarbonyl as an N-Terminal Group Conferring High Affinity to the Minimal Phosphopeptide Sequence Recognized by the Grb2-SH2 Domain

1997 • 57 citations

Potent Antagonists of the SH2 Domain of Grb2: Optimization of the X₊₁ Position of 3-Amino-Z-Tyr(PO₃H₂)-X₊₁-Asn-NH₂

1998 • 45 citations

Unusual aspect of the dimerization of N-vinylcarbazole by redox reactions. Participation of molecular oxygen

1970 • 14 citations