Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder

When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders

2003 • 1,155 citations

Impaired Fasting Glucose Tolerance in First-Episode, Drug-Naive Patients With Schizophrenia

2003 • 834 citations

Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders

2002 • 404 citations

The 24-Hour Profile of Adrenocorticotropin and Cortisol in Major Depressive Illness*

1985 • 401 citations

Improvement in Mood and Fatigue after Dehydroepiandrosterone Replacement in Addison’s Disease in a Randomized, Double Blind Trial

2000 • 360 citations

DST Studies in Psychotic Depression: A Meta-Analysis

1997 • 347 citations

Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder

2004 • 342 citations

Anti-glucocorticoid effects of dehydroepiandrosterone (DHEA)

1994 • 318 citations

Improvements in Neurocognitive Function and Mood Following Adjunctive Treatment with Mifepristone (RU-486) in Bipolar Disorder

2004 • 308 citations

Dissecting human adrenal androgen production

2002 • 260 citations

Evidence of basal pituitary–adrenal overactivity in first episode, drug naïve patients with schizophrenia

2003 • 228 citations

Elevation of the Cortisol-Dehydroepiandrosterone Ratio in Drug-Free Depressed Patients

2002 • 207 citations

Dehydroepiandrosterone Augmentation in the Management of Negative, Depressive, and Anxiety Symptoms in Schizophrenia

2003 • 204 citations

Altered salivary dehydroepiandrosterone levels in major depression in adults

2000 • 200 citations

Pituitary volume in psychosis

2004 • 183 citations

Dehydroepiandrosterone Protects Hippocampal Neurons Against Neurotoxin‐Induced Cell Death: Mechanism of Action²

1999 • 172 citations

Reduced glucocorticoid and estrogen receptor alpha messenger ribonucleic acid levels in the amygdala of patients with major mental illness

2004 • 159 citations

Neuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and Therapeutics

2005 • 158 citations

Combined dexamethasone/corticotropin-releasing hormone test in patients with schizophrenia and in normal controls: II

1995 • 156 citations

Increased Pituitary Volume in Antipsychotic-Free and Antipsychotic-Treated Patients of the Æsop First-Onset Psychosis Study

2005 • 152 citations

Elevation of the cortisol/dehydroepiandrosterone ratio in schizophrenia patients

2003 • 142 citations

Abnormal dexamethasone suppression test results in chronic schizophrenic patients

1982 • 139 citations

Stress Hormone-Related Psychopathology: Pathophysiological and Treatment Implications

2001 • 138 citations

Neuro(active)steroids actions at the neuromodulatory sigma1 (σ1) receptor: Biochemical and physiological evidences, consequences in neuroprotection

2006 • 127 citations

Effect of Dehydroepiandrosterone Replacement on Insulin Sensitivity and Lipids in Hypoadrenal Women

2005 • 114 citations

Assessing cortisol and dehydroepiandrosterone (DHEA) in saliva: effects of collection method

2006 • 114 citations

Depression in schizophrenia: a comparison of three measures

1996 • 107 citations

Increased circulatory dehydroepiandrosterone and dehydroepiandrosterone-sulphate in first-episode schizophrenia: relationship to gender, aggression and symptomatology

2004 • 91 citations

Dehydroepiandrosterone: Antiglucocorticoid Action in Mice

1992 • 79 citations

A Single Administration of Dehydroepiandrosterone Does Not Enhance Memory Performance in Young Healthy Adults, but Immediately Reduces Cortisol Levels

1997 • 65 citations

Improvement of Sustained Attention and Visual and Movement Skills, but Not Clinical Symptoms, After Dehydroepiandrosterone Augmentation in Schizophrenia

2006 • 64 citations

Effects of adjunctive mifepristone (RU-486) administration on neurocognitive function and symptoms in schizophrenia

2004 • 61 citations

The Mean 1300-1600 h Plasma Cortisol Concentration as a Diagnostic Test for Hypercortisolism*

1982 • 55 citations

The native anti-glucocorticoid paradigm

2006 • 53 citations

Improvement of extrapyramidal symptoms following dehydroepiandrosterone (DHEA) administration in antipsychotic treated schizophrenia patients: A randomized, double-blind placebo controlled trial

2005 • 52 citations

Cortisol/Dehydroepiandrosterone Ratio and Responses to Antipsychotic Treatment in Schizophrenia

2005 • 52 citations

Dehydroepiandrosterone replacement therapy

2001 • 51 citations

Serial dexamethasone suppression tests among rapidly cycling bipolar patients.

1982 • 49 citations

Possible dihydroepiandrosterone-induced mania

1999 • 46 citations

Plasma dehydroepiandrosterone levels are strongly increased in schizophrenia

2004 • 43 citations

The Use of Dehydroepiandrosterone Therapy in Clinical Practice

2005 • 39 citations

Prasterone (DHEA) and Mania

2000 • 38 citations

Clozapine decreases rat brain dehydroepiandrosterone and dehydroepiandrosterone sulfate levels

2002 • 34 citations

Differential blockade of gamma-aminobutyric acid type A receptors by the neuroactive steroid dehydroepiandrosterone sulfate in posterior and intermediate pituitary.

1999 • 21 citations

DHEA and the Brain

2002 • 19 citations

[A case report of mania precipitated by use of DHEA].

2002 • 18 citations

Chronic lithium treatment affects rat brain and serum dehydroepiandrosterone (DHEA) and DHEA-sulphate (DHEA-S) levels

2004 • 16 citations