Ferritin: Molecular structure and iron-storage mechanisms

Kinetics of Precipitation.

1965 • 879 citations

Inorganic Biochemistry

1974 • 834 citations

Kinetics of precipitation

1964 • 777 citations

Protein crystallography

1977 • 713 citations

On ferritin heterogeneity. Further evidence for heteropolymers.

1978 • 464 citations

Mineralogical constitution of colloidal “hydrous ferric oxides”

1967 • 443 citations

Protein disk of tobacco mosaic virus at 2.8 Å resolution showing the interactions within and between subunits

1978 • 406 citations

Gann monograph on cancer research

1971 • 384 citations

Regulation of Synthesis and Turnover of Ferritin in Rat Liver

1966 • 329 citations

An electron microscopic study of ferritin

1954 • 314 citations

Preferential Synthesis of Ferritin and Albumin by Different Populations of Liver Polysomes

1969 • 301 citations

Proteins of Iron Storage and Transport in Biochemistry and Medicine

1976 • 288 citations

Proteins of iron metabolism

1977 • 282 citations

Ferritin: Its Properties and Significance for Iron Metabolism.

1946 • 266 citations

Iron in Biochemistry and Medicine

1975 • 265 citations

Electron density map of apoferritin at 2.8-Å resolution

1978 • 264 citations

The Hydrolytic Polymerization of Iron(III)

1966 • 250 citations

The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake

1972 • 244 citations

Ferric Oxyhydroxide Core of Ferritin

1967 • 202 citations

Mechanism and kinetics of iron release from ferritin by dihydroflavins and dihydroflavin analogs

1978 • 194 citations

Significance of intermediary plateau regions in enzyme saturation curves

1969 • 184 citations

The release of iron from horse spleen ferritin by reduced flavins

1974 • 182 citations

Azotobacter cytochrome b557.5 is a bacterioferritin

1979 • 175 citations

On the Measurement of Protein Turnover in Animal Cells

1972 • 162 citations

Polynuclear complexes of iron and their biological implications

2008 • 153 citations

The structure of apoferritin: Molecular size, shape and symmetry from X-ray data

1963 • 146 citations

FERRITIN

1943 • 141 citations

Properties of human tissue isoferritins

1978 • 135 citations

Ferritin iron uptake and release. Structure–function relationships

1974 • 133 citations

Incorporation and release of inorganic phosphate in horse spleen ferritin

1978 • 128 citations

On the structure of hemosiderin and its relationship to ferritin

1971 • 126 citations

Binding of Human Serum Ferritin to Concanavalin A

1979 • 118 citations

The catalytic activity of horse spleen apoferritin. Preliminary kinetic studies and the effect of chemical modification

1973 • 113 citations

Isolation and Characterization of Iron‐Binding Proteins from Rat Intestinal Mucosa

1976 • 113 citations

Carcino-Foetal Human Liver Ferritins

1973 • 103 citations

Immunologic differences in human isoferritins: implications for immunologic quantitation of serum ferritin

1977 • 101 citations

The structures of ferritin and apoferritin: Some preliminary X-ray data

1959 • 98 citations

Structure of cytochrome c′: a dimeric, high-spin haem protein

1980 • 98 citations

Ferritin

2007 • 97 citations

The Determination of the Structures of Complex Molecules and Ions from X-Ray Diffraction by Their Solutions: The Structures of the Groups PtBr₆^--, PtCl₆^--, Nb₆Cl₁₂⁺⁺, Ta₆Br₁₂⁺⁺, and Ta₆Cl₁₂⁺⁺

1950 • 96 citations

The oxidation of ferrous perchlorate by molecular oxygen

1954 • 96 citations

The structure of iron (III) oxide-hydrate gels

1966 • 92 citations

The iron oxide core of the ferritin molecule

1965 • 91 citations

The Subunit Structure of Horse Spleen Apoferritin

1971 • 91 citations

FERRITIN

1944 • 87 citations

Subunit interactions in horse spleen apoferritin. Dissociation by extremes of pH

1973 • 86 citations

The structure of an iron core analog of ferritin

1968 • 86 citations

Ferritin on the surface of lymphocytes in Hodgkin's disease patients. A possible blocking substance removed by levamisole.

1977 • 84 citations

The organ-specificity of ferritin in human and horse liver and spleen

1973 • 82 citations

Ferritin: Iron incorporation and iron release

1970 • 81 citations

A Mossbauer determination of the iron core particle size distribution in ferritin

1978 • 80 citations

Denaturation of horse spleen ferritin in aqueous guanidinium chloride solutions

1972 • 80 citations

Reassembly of Apoferritin Molecules from Subunits

1968 • 76 citations

Structure of the iron-containing core in ferritin by the extended x-ray absorption fine structure technique

1979 • 75 citations

Quaternary and tertiary structure of haemerythrin

1975 • 73 citations

Ferritin synthesis in normal and leukaemic leukocytes

1974 • 73 citations

The formation of ferritin from apoferritin. Catalytic action of apoferritin

1973 • 73 citations

Isolation and characterization of phytoferritin from pea (Pisum sativum) and Lentil (Lens esculenta)

1978 • 72 citations

Structure of horse-spleen apoferritin at 6 Å resolution

1975 • 66 citations

Ferritin in Human Liver Cells of Homozygous Beta‐Thalassaemia: Ultrastructural Observations

1977 • 66 citations

Invertebrate Ferritin: Occurrence in Mollusca

1963 • 65 citations

Native and subunit molecular weights of apoferritin

1971 • 64 citations

Mechanism of oxygenation of ferrous ion in neutral solution

1970 • 63 citations

FERRITIN IN THE FUNGUS PHYCOMYCES

1971 • 62 citations

Low angle neutron scattering of ferritin studied by contrast variation

1976 • 62 citations

The formation of ferritin from apoferritin. Inhibition and metal ion-binding studies

1973 • 62 citations

In vitro reconstitution of ferritin

1968 • 59 citations

The Kinetics of Serum and Tissue Ferritins: Relation to Carbohydrate Content

1979 • 59 citations

Reversible Association of Apoferritin Molecules. Comparison of Light-Scattering and Other Data^*

1967 • 58 citations

Pseudosymmetry in the structure of myohemerythrin.

1977 • 57 citations

The Treatment of Haemochromatosis with Desferrioxamine

1963 • 57 citations

Compartmentation of albumin and ferritin synthesis in rat liver in vivo

1976 • 57 citations

The significance of abrupt transitions in Lineweaver–Burk plots with particular reference to glutamate dehydrogenase. Negative and positive co-operativity in catalytic rate constants

1973 • 55 citations

Ferritin and Apoferritin

1947 • 53 citations

The structural relationship between ferritin protein and its mineral core

1969 • 53 citations

Chemical Modification as a Probe of the Topography and Reactivity of Horse‐Spleen Apoferritin

1976 • 53 citations

M?ssbauer Effect In Ferritin

1966 • 53 citations

Synthetisches Ferritin, ein Elsen(III)-komplex des Apoferritins

1955 • 52 citations

Ferritin as a Cytosol Iron Transport Intermediate in Human Reticulocytes

1979 • 52 citations

A novel mechanism for ferritin iron oxidation and deposition

1978 • 49 citations

Acute Intestinal Iron Intoxication

1955 • 48 citations

Mechanism of sex difference in rat tissue iron stores

1973 • 48 citations

The effect of pH on the kinetics of the reaction of iron(II) with hydrogen peroxide in perchlorate media

1968 • 47 citations

Heterogeneity of horse spleen ferritin and apoferritin: Comparison of electrophoretic and chromatographic fractions

1965 • 47 citations

Iron exchange between ferritin and transferrin in vitro

1978 • 47 citations

NADH-FMN Oxidoreductase Activity and Iron Content of Organs from Riboflavin- and Iron-Deficient Rats

1977 • 47 citations

Similarity of the structure of ferritin and iron . dextran (imferon) determined by extended X-ray absorption fine structure analysis.

1979 • 46 citations

Denaturation of ferritin and its relationship with hemosiderin

1963 • 45 citations

The structure of apoferritin: Amino acid composition and end-groups

1962 • 44 citations

Correlations between subunit distribution, microheterogeneity, and iron content of human liver ferritin

1978 • 40 citations

Synthesis of liver ferritin on free and membrane‐bound polyribosomes of different sizes

1973 • 40 citations

FERRITIN

1943 • 40 citations

Mucosal transferrin and ferritin factors in the regulation of iron absorption

1977 • 40 citations

The binding of ferric iron by ferritin

1979 • 39 citations

The ultrastructure of ferritin macromolecules

1978 • 37 citations

Studies on the utilization of ferritin iron in the ferrochelatase reaction of isolated rat liver mitochondria

1978 • 37 citations

Structure of methemerythrin at 5 Å resolution

1976 • 37 citations

Mobilization of iron from the plasma membrane of the murine reticulocyte. The role of ferritin

1978 • 37 citations

The iron content of human liver and spleen isoferritins correlates with their isoelectric point and subunit composition

1978 • 37 citations

Uptake and release of ferritin iron. Surface effects and exchange within the crystalline core

1974 • 36 citations

Carbohydrate composition of horse spleen ferritin

1975 • 36 citations

Crystallization of Ferritin from Coelomic Fluid of Corbicula sandai with Ammonium Sulfate

1969 • 35 citations

Mechanism of iron induction of ferritin synthesis

1975 • 34 citations

THE STRUCTURE AND COMPOSITION OF HEMOSIDERIN

1929 • 32 citations

Amphibian Red Blood Cell Ferritin

1973 • 32 citations

Stoichiometry of iron oxidation by apoferritin

1978 • 32 citations

Subunit Heterogeneity in Rat Liver Apoferritin

1974 • 32 citations

Subunit heterogeneity in ferritin

1973 • 31 citations

Structural differences in ferritins from normal and malignant rat tissues

1975 • 31 citations

Horse spleen hemosiderin

1964 • 30 citations

Ferritin, a Sensitizing Substance in the Leucocyte Migration Inhibition Test in Patients with Malignant Lymphoma

1979 • 30 citations

Variable stoichiometry of Fe(II)‐oxidation in ferritin

1978 • 29 citations

Hydrogen ion interactions of horse spleen ferritin and apoferritin.

1976 • 29 citations

Alterations in tissue ferritins in iron storage disorders.

1975 • 28 citations

Biosynthesis of ferritin in rat hepatoma cells and rat livers. I. Synthesis and assembly of protein subunits of ferritin.

1977 • 27 citations

Spectral studies of the ferritin core and related iron(III) polymers

1974 • 27 citations

Ferritin iron mobilisation by chelating agents

1980 • 27 citations

In vitro stimulation of apoferritin synthesis by iron

1975 • 27 citations

A kinetic study of the mechanism of ferritin formation: the effects of buffer, of pH, and of the iron content of the molecule

1979 • 27 citations

Optical rotatory dispersion and circular dichroism studies on ferritin and apoferritin

1971 • 26 citations

The Uptake of Ferric Iron by Rat Liver Ferritin in Vivo and in Vitro

1976 • 26 citations

The isolation and properties of porcine ferritin and apoferritin

1977 • 26 citations

Variation in the distribution of two human heart ferritin species. Isoferritin profile and subunit composition in normal and iron-overloaded subjects

1977 • 25 citations

Oxidant specificity in ferritin formation

1979 • 25 citations

Crystal structures of hen egg-white lysozyme complexes with gadolinium(III) and gadolinium(III)-N-acetyl-<scp>d</scp>-glucosamine

1979 • 24 citations

Effect of Riboflavin Deficiency on Activity of NADH-FMN Oxidoreductase (Ferriductase) and Iron Content of Rat Liver

1977 • 24 citations

Studies on the mechanism of ferritin formation

1978 • 23 citations

Structural features of rat cardiac ferritins

1977 • 22 citations

Electron micrographs of ferritin and apoferritin molecules

1960 • 21 citations

Comparison of the physical properties of chemically prepared and tissue-endogenous equine apoferritins.

1976 • 20 citations

Artifacts in ferritin isoelectric focussing profiles

1979 • 19 citations

The properties of Corbicula sandai apoferritin

1977 • 19 citations

Iron binding to apoferritin: A fluorescence spectroscopy study

1976 • 18 citations

Synthesis of ferritin in cultured hepatoma cells

1974 • 17 citations

A reappraisal of the electrophoretic patterns obtained from ferritin and apoferritin in the presence of denaturants

1978 • 16 citations

Biosynthesis of ferritin in rat hepatoma cells and rat livers. II. Binding of iron by ferritin protein.

1977 • 16 citations

Rate of Release of Iron from Ferritin to 1,10-Phenanthroline

1967 • 15 citations

Metal chelation — Principles and applications

1978 • 14 citations

Sex difference in distribution and iron responsiveness of the two ferritins of rat cardiac and skeletal muscle

1977 • 14 citations

Production of ferritin by rat hepatoma cells in vitro. Demonstration of protein subunits and ferritin by immunofluorescence.

1975 • 11 citations

A Mechanism for Ferritin-Iron Oxidation and Deposition

1977 • 11 citations

Presence of Ferritin in a Marine Elasmobranch, Scyllium canicula

1952 • 10 citations

A Study of Storage Iron in the Pregnant Rat

1971 • 10 citations

Inhibition by Zinc Ions of Ferritin Formation in vitro

1973 • 10 citations

The incorporation of 59Fe, [3H]leucine and [32P]inorganic phosphate in ferritin during the perfusion of isolated rat livers

1972 • 9 citations

A tetragonal crystal form of horse spleen apoferritin and its relationship to the cubic modification

1974 • 5 citations

Two of the Newer ‘Gastrointestinal Hormones’

1979 • 5 citations

Primary structure of rat liver apoferritin

1978 • 5 citations

Iron Metabolism and Its Disorders

1977 • 2 citations