Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: An in vivo autoradiographic study

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1983 • 2,149 citations

The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluorescence study in the rat

1982 • 1,693 citations

Efferent connections of the substantia nigra and ventral tegmental area in the rat

1979 • 1,278 citations

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

1985 • 1,253 citations

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1984 • 1,092 citations

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1984 • 913 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

Organization of the amygdalopetal projections from modality‐specific cortical association areas in the monkey

1980 • 533 citations

Brainstem innervation of prefrontal and anterior cingulate cortex in the rhesus monkey revealed by retrograde transport of HRP

1982 • 353 citations

Computerized densitometry and color coding of [¹⁴C] deoxyglucose autoradiographs

1980 • 345 citations

INFLUENCE OF THE SUBSTANTIA NIGRA ON THE CATECHOLAMINE CONTENT OF THE STRIATUM

1965 • 340 citations

Hemiparkinsonism in monkeys after unilateral internal carotid artery artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

1986 • 309 citations

Selectivity of the Parkinsonian Neurotoxin MPTP: Toxic Metabolite MPP ⁺ Binds to Neuromelanin

1986 • 289 citations

Monoamine distribution in primate brain V. Monoaminergic nuclei: Anatomy, pathways and local organization

1983 • 245 citations

Monoamine distribution in primate brain. V. Monoaminergic nuclei: Anatomy, pathways, and local organization

1982 • 244 citations

Further evidence for the presence of nigro‐neostriatal dopamine neurons in the rat

1965 • 234 citations

Region‐specific distribution of catecholamine afferents in primate cerebral cortex: A fluorescence histochemical analysis

1984 • 185 citations

A brainstem atlas of catecholaminergic neurons and serotonergic perikarya in a pygmy primate (Cebuella pygmaea)

1978 • 113 citations

CORRESPONDENCE OF MELANIN-PIGMENTED NEURONS IN HUMAN BRAIN WITH A1–A14 CATECHOLAMINE CELL ROUPS

1982 • 106 citations

Injury of nigral neurons exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A tyrosine hydroxylase immunocytochemical study in monkey

1986 • 102 citations

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

1988 • 82 citations

N-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP) causes destruction of the nigrostriatal but not the mesolimbic dopamine system in the monkey.

1984 • 75 citations

Histochemical mapping of catecholaminergic neurons and their ascending fiber pathways in the rhesus monkey brain

1982 • 69 citations

Hemiparkinsonism in monkeys after unilateral caudate nucleus infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): behavior and histology

1988 • 59 citations

A Stereotaxic Atlas of the Monkey Brain

1962 • 57 citations

Quantitative autoradiography of the rat brain vesicular monoamine transporter using the binding of [3H]dihydrotetrabenazine and 7-amino-8-[125I]iodoketanserin

1989 • 53 citations

Uptake inhibition protects nigro-striatal dopamine neurons from the neurotoxicity of 1-methyl-4-phenylpyridine (MPP+) in mice

1986 • 37 citations

Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates

1988 • 32 citations

Recommended safe practices for using the neurotoxin MPTP in animal experiments.

1988 • 32 citations

Metabolism of [14C]MPTP in mouse and monkey implicates MPP+ and not bound metabolites as the operative neurotoxin

1988 • 32 citations

Uptake, Release, and Subcellular Localization of l‐Methyl‐4‐Phenylpyridinium in Blood Platelets

1987 • 20 citations

Juvenile parkinsonism: A patient with possible primary striatal dysfunction

1978 • 16 citations

MPTP, impairment of motor performance and amine accumulation in Macaca fasicularis

1987 • 8 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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