Solution structure of the calcium channel antagonist ω‐conotoxin GVIA

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Two-dimensional spectroscopy. Application to nuclear magnetic resonance

1976 • 3,023 citations

Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy

1983 • 2,638 citations

A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants

1982 • 2,567 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

Searching for Peptide Ligands with an Epitope Library

1990 • 2,080 citations

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

1991 • 1,888 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Multiple quantum filters for elucidating NMR coupling networks

1982 • 1,780 citations

A new type of synthetic peptide library for identifying ligand-binding activity

1991 • 1,769 citations

Elucidation of cross relaxation in liquids by two-dimensional N.M.R. spectroscopy

1980 • 1,490 citations

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1983 • 1,329 citations

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

1991 • 1,319 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

Determination of three‐dimensional structures of proteins from interproton distance data by hybrid distance geometry‐dynamical simulated annealing calculations

1988 • 775 citations

Peptide Neurotoxins from Fish-Hunting Cone Snails

1985 • 742 citations

Chain reversals in proteins

1973 • 652 citations

Experimental techniques of two-dimensional correlated spectroscopy

1980 • 598 citations

β-Sheet topology and the relatedness of proteins

1977 • 541 citations

Diversity of Conus Neuropeptides

1990 • 537 citations

β-Hairpin families in globular proteins

1985 • 533 citations

A new conus peptide ligand for mammalian presynaptic Ca2+ channels

1992 • 487 citations

Exploring nuclear spin systems by relayed magnetization transfer

1982 • 475 citations

Purification and sequence of a presynaptic peptide toxin from Conus geographus venom

1984 • 416 citations

Improved solvent suppression in one- and two-dimensional NMR spectra by convolution of time-domain data

1989 • 403 citations

Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using .omega.-conotoxin from Conus magus venom

1987 • 337 citations

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

1986 • 321 citations

Refined crystal structure of the potato inhibitor complex of carboxypeptidase A at 2.5 Å resolution

1982 • 260 citations

P.E.COSY, a simple alternative to E.COSY

1987 • 257 citations

PEPTIDE TOXINS FROM VENOMOUS CONUS SNAILS

1988 • 234 citations

Sampling and efficiency of metric matrix distance geometry: A novel partial metrization algorithm

1992 • 204 citations

Calculation of molecular volumes and areas for structures of known geometry

1985 • 196 citations

Conformations of disulfide bridges in proteins

1990 • 195 citations

Stereospecific assignments of side‐chain protons and characterization of torsion angles in Eglin c

1987 • 187 citations

Constant and hypervariable regions in conotoxin propeptides.

1990 • 183 citations

Conotoxins.

1991 • 150 citations

Characterization of the .omega.-conotoxin target. Evidence for tissue-specific heterogeneity in calcium channel types

1987 • 143 citations

Omega-conotoxin GVIA binding to a high-affinity receptor in brain: characterization, calcium sensitivity, and solubilization

1988 • 142 citations

Novel .alpha.- and .omega.-conotoxins and Conus striatus venom

1992 • 138 citations

Determination of the complete three-dimensional structure of the trypsin inhibitor from squash seeds in aqueous solution by nuclear magnetic resonance and a combination of distance geometry and dynamical simulated annealing

1989 • 128 citations

Solution structure of .omega.-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis

1993 • 107 citations

Proton 2D NMR and distance geometry study of the folding of Ecballium elaterium trypsin inhibitor, a member of the squash inhibitors family

1989 • 95 citations

A molluskivorous Conus toxin: conserved frameworks in conotoxins

1989 • 95 citations

Analysis of 1H NMR spectra of proteins using multiple-quantum coherence

1986 • 77 citations

Identification of the receptor for omega-conotoxin in brain. Probable components of the calcium channel.

1987 • 63 citations

Use of restrained molecular dynamics in water to determine three‐dimensional protein structure: Prediction of the three‐dimensional structure of Ecballium elaterium trypsin inhibitor II

1989 • 62 citations

Three-Dimensional Structure of ω-Conotoxin GVIA Determined by 1H-NMR

1993 • 57 citations

A study of the NH NMR signals of Gly-Gly-X-Ala tetrapeptides in H2O at low temperature.

1986 • 49 citations

Precursor structure of ω-conotoxin GVIA determined from a cDNA clone

1992 • 46 citations

The polyamine spermine affects ω‐conotoxin binding and function at N‐type voltage‐sensitive calcium channels

1990 • 36 citations

Calcium Channel-Targeted Polypeptide Toxins

1991 • 31 citations

Synthesis and secondary-structure determination of omega-conotoxin GVIA: a 27-peptide with three intramolecular disulfide bonds.

1986 • 30 citations

Effects of site-specific acetylation on .omega.-conotoxin GVIA binding and function

1993 • 25 citations

Improvement of relayed—NOESY type experiments by implantation of spin‐lock sequences

1988 • 11 citations