Induction, activation and inhibition of epoxide hydrase: an anomalous prevention of chlorobenzene-induced hepatotoxicity by an inhibitor of epoxide hydrase

Improved method for the determination of blood glutathione.

1963 • 6,733 citations

1,2-Naphthalene oxide as an intermediate in the microsomal hydroxylation of naphthalene. V

1970 • 428 citations

A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide

1971 • 414 citations

Possible Mechanism of Liver Necrosis Caused by Aromatic Organic Compounds

1971 • 382 citations

Hepatic epoxide hydrase. Structure-activity relations for substrates and inhibitors

1971 • 316 citations

Role of the arene oxide-oxepin system in the metabolism of aromatic substrates

1968 • 215 citations

In Vitro Transformation of Rodent Cells by K-Region Derivatives of Polycyclic Hydrocarbons

1971 • 190 citations

An epoxide is an intermediate in the microsomal metabolism of the chemical carcinogen, dibenz(a,h)anthracene

1971 • 172 citations

Conversion of naphthalene to trans-naphthalene dihydrodiol: Evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes

1972 • 151 citations

Epoxides as Obligatory Intermediates in the Metabolism of Olefins to Glycols

1970 • 111 citations

Epoxide intermediates in microsomal oxidation of olefins to glycols.

1970 • 111 citations

Solubilization, purification, and properties of a hepatic epoxide hydrase

1971 • 105 citations

Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: Evidence for homologous enzymes

1971 • 100 citations

Effects of metyrapone on liver microsomal drug oxidations.

1969 • 98 citations

3-methylcholanthrene blocks hepatic necrosis induced by administration of bromobenzene or carbon tetrachloride

1971 • 82 citations

The Growth of Fetal Mouse Skin in Cell Culture and Transplantation to F1 Mice**From the Experimental Pathology Branch, National Cancer InstituLe, Bethesda, Maryland 20014.

1970 • 75 citations

Aryl hydrocarbon hydroxylase, epoxide hydrase, and 7,12-dimethylbenz(a)anthracene-produced skin tumorigenesis in the mouse.

1972 • 67 citations

A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: Presence of epoxide hydrase in cytochrome P-450 and P-448 fractions

1972 • 64 citations

�ber die Wirkung von Metyrapon auf den mikrosomalen Arzneimittelabbau

1967 • 59 citations

Induced synthesis of oxidative enzymes in liver microsomes by polycyclic hydrocarbons and drugs

1963 • 59 citations

Synthesis of 1-arylimidazoles, a new class of steroid hydroxylation inhibitors

1969 • 57 citations

Deuterium migration during the acid-catalyzed dehydration of 6-deuterio-5,6-dihydroxy-3-chloro-1,3-cyclohexadi-ene, a nonenzymic model for the NIH shift

1967 • 35 citations

A simple radiometric assay for microsomal aryl hydroxylase activity

1970 • 23 citations

Studies on modifiers of microsomal drug oxidation

1971 • 18 citations

Role of hepatic microsomal ethanol metabolism

1971 • 6 citations