A protein factor that enhances amsacrine-mediated formation of topoisomerase II-DNA complexes in murine mastocytoma cell nuclei

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

1985 • 2,298 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1985 • 751 citations

Cleavage of DNA by mammalian DNA topoisomerase II.

1983 • 539 citations

Metaphase chromosome structure

1986 • 538 citations

Localization of topoisomerase II in mitotic chromosomes.

1985 • 501 citations

A glimpse at chromosomal order

1987 • 423 citations

Purification of topoisomerase II from amsacrine-resistant P388 leukemia cells. Evidence for two forms of the enzyme.

1987 • 282 citations

DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II.

1986 • 241 citations

Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases

1981 • 231 citations

Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells.

1985 • 174 citations

Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei

1983 • 165 citations

Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II

1986 • 145 citations

A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells

1979 • 144 citations

Topoisomerase-specific drug sensitivity in relation to cell cycle progression.

1987 • 144 citations

Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents

1984 • 139 citations

Inhibition of calf thymus type II DNA topoisomerase by poly(ADP-ribosylation).

1985 • 126 citations

Cell cycle stage-dependent variations in drug-induced topoisomerase II mediated DNA cleavage and cytotoxicity

1987 • 103 citations

Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity.

1988 • 77 citations

The formation and resealing of intercalator-induced DNA strand breaks in isolated L1210 cell nuclei

1982 • 73 citations

Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes

1988 • 50 citations

Abrogation of etoposide-mediated cytotoxicity by cycloheximide

1988 • 40 citations

Mechanism of resistance of non-cycling mammalian cells to 4′-[9-acridinylamino]methanesulphon-m-anisidide: Role of DNA topoisomerase II in log- and plateau-phase CHO cells

1988 • 24 citations

Production of protein-associated DNA breaks by 10-[diethylaminopropylamino]-6-methyl-5H-pyrido[3',4':4,5]pyrrolo [2,3-g]isoquinoline in cultured L1210 cells and in isolated nuclei: comparison with other topoisomerase II inhibitors.

1988 • 24 citations

Dominant versus recessive behavior of a cold- and a heat-sensitive mammalian cell cycle variant in heterokaryons

1981 • 20 citations

Stimulatory and inhibitory effects of extracts from mammalian cell-cycle mutants on DNA replication in partially lysed cells

1985 • 6 citations

Relationship between sensitivity to 4′-(9-acridinylamino)methanesulfon-m-anisidide and DNA topoisomerase II in a cold-sensitive cell-cycle mutant of a murine mastocytoma cell line

1988 • 6 citations