A Novel Function for the Second C2 Domain of Synaptotagmin

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

1994 • 1,485 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

1992 • 968 citations

A 38,000-dalton membrane protein (p38) present in synaptic vesicles.

1985 • 856 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Calcium dependence of the rate of exocytosis in a synaptic terminal

1994 • 746 citations

Calcium Action in Synaptic Transmitter Release

1987 • 742 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins

1995 • 597 citations

Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin

1993 • 551 citations

Sequence similarity of phospholipase C with the non-catalytic region of src

1988 • 541 citations

Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.

1993 • 540 citations

Two components of transmitter release at a central synapse.

1994 • 528 citations

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.

1993 • 486 citations

Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling

1994 • 483 citations

Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.

1995 • 455 citations

Rabphilin-3A, a Putative Target Protein for smg p25A/rab3A p25 Small GTP-Binding Protein Related to Synaptotagmin

1993 • 386 citations

Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1

1995 • 372 citations

Domain structure of synaptotagmin (p65)

1991 • 350 citations

A marker of early amacrine cell development in rat retina

1985 • 326 citations

Genetic and electrophysiological studies of drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission

1995 • 321 citations

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 • 288 citations

Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants.

1994 • 286 citations

rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin.

1995 • 269 citations

Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin.

1993 • 253 citations

The effect on synaptic physiology of synaptotagmin mutations in drosophila

1994 • 253 citations

Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis

1991 • 251 citations

Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II.

1994 • 244 citations

Synaptotagmin II. A novel differentially distributed form of synaptotagmin

1991 • 231 citations

Association of Rab3A with synaptic vesicles at late stages of the secretory pathway.

1991 • 222 citations

The N-Ethylmaleimide-sensitive Fusion Protein and α-SNAP Induce a Conformational Change in Syntaxin

1995 • 210 citations

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

1994 • 209 citations

Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission.

1994 • 206 citations

Synaptotagmin III is a novel isoform of rat synaptotagmin expressed in endocrine and neuronal cells.

1994 • 143 citations

Identification of a nonneuronal isoform of synaptotagmin.

1995 • 74 citations

A third synaptotagmin gene, Syt3, in the mouse.

1994 • 74 citations

Mice sans synaptotagmin

1994 • 38 citations