Relationship of Virologic, Immunologic, and Clinical Parameters in Infants with Vertically Acquired Human Immunodeficiency Virus Type 1 Infection

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Biologic Features of HIV-1 That Correlate with Virulence in the Host

1988 • 679 citations

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

1989 • 662 citations

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

1988 • 621 citations

ASSOCIATION BETWEEN BIOLOGICAL PROPERTIES OF HUMAN IMMUNODEFICIENCY VIRUS VARIANTS AND RISK FOR AIDS AND AIDS MORTALITY

1989 • 581 citations

REPLICATIVE CAPACITY OF HUMAN IMMUNODEFICIENCY VIRUS FROM PATIENTS WITH VARYING SEVERITY OF HIV INFECTION

1986 • 536 citations

A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

1989 • 536 citations

A Prospective Study of Infants Born to Women Seropositive for Human Immunodeficiency Virus Type 1

1989 • 517 citations

AMPLIFICATION OF RNA

1990 • 486 citations

Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals

1993 • 464 citations

Survival in Children with Perinatally Acquired Human Immunodeficiency Virus Type 1 Infection

1989 • 430 citations

Prognostic factors and survival in children with perinatal HIV-1 infection

1992 • 356 citations

HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay

1992 • 353 citations

Longitudinal Study of 94 Symptomatic Infants With Perinatally Acquired Human Immunodeficiency Virus Infection

1990 • 262 citations

Simple, sensitive, and specific detection of human immunodeficiency virus type 1 in clinical specimens by polymerase chain reaction with nested primers

1990 • 256 citations

ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)-FREE TIME AFTER HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) SEROCONVERSION IN HOMOSEXUAL MEN

1989 • 206 citations

The structure of medicine.

1948 • 200 citations

Incubation periods for paediatric AIDS patients

1988 • 196 citations

Detection and Quantification of Human Immunodeficiency Virus RNA in Patient Serum by Use of the Polymerase Chain Reaction

1991 • 163 citations

DETECTION OF HUMAN IMMUNODEFICIENCY VIRUS

1990 • 146 citations

Features of children perinatally infected with HIV-1 surviving longer than 5 years

1994 • 145 citations

Transmission of Human Immunodeficiency Virus Type 1 (HIV-1) from Mother to Child Correlates with Viral Phenotype

1993 • 133 citations

Viral measurement by polymerase chain reaction-based assays in human immunodeficiency virus-infected infants

1995 • 128 citations

Human immunodeficiency virus type 1 detected in all seropositive symptomatic and asymptomatic individuals

1990 • 110 citations

Deficient human immunodeficiency virus type 1-specific cytotoxic T cell responses in vertically infected children

1991 • 107 citations

HIV-1 biological phenotype and the development of zidovudine resistance in relation to disease progression in asymptomatic individuals during treatment

1992 • 97 citations

Pneumocystis cariniiPneumonia in Infants Infected with the Human Immunodeficiency Virus with More Than 450 CD4 T Lymphocytes per Cubic Millimeter

1990 • 90 citations

Natural History and Serologic Diagnosis of Infants Born to Human Immunodeficiency Virus–Infected Women

1989 • 84 citations

Clinical Significance of Human Immunodeficiency Virus Type 1 Phenotypes in Infected Children

1994 • 75 citations

Pediatric AIDS: Problems within Problems

1990 • 72 citations

Immunological and serological markers predictive of progression to AIDS in a cohort of HIV-infected drug users

1990 • 69 citations

Immunologic characterization of children vertically infected with human immunodeficiency virus, with slow or rapid disease progression

1995 • 64 citations

Replication and tropism of human immunodeficiency virus type 1 as predictors of disease outcome in infants with vertically acquired infection

1993 • 54 citations

Trends in survival for children reported with maternally transmitted acquired immunodeficiency syndrome in New York City, 1982 to 1989

1992 • 37 citations

Plasma viraemia as a marker of viral replication in HIV-infected individuals

1991 • 33 citations

Perinatal infection by human immunodeficiency virus type 1 (HIV–1): Relationship between proviral copy number in vivo, viral properties in vitro, and clinical outcome

1991 • 30 citations

Sensitive microculture method for isolation of human immunodeficiency virus type 1 from blood leukocytes

1992 • 22 citations

Quantification of low levels of human immunodeficiency virus (HIV) type 1 RNA in P24 antigen-negative, asymptomatic, HIV-positive patients by PCR

1996 • 13 citations

HIV-1 isolates from children with or without AIDS have similar in vitro biologic properties

1993 • 13 citations

Pentoxifylline preferentially inhibits interleukin-10 production by HIV-1 -infected human T cells

1994 • 8 citations