Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo

PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

1999 • 1,165 citations

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

1999 • 819 citations

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

1997 • 798 citations

Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery

1996 • 583 citations

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells

1998 • 568 citations

A Powerful Nonviral Vector for In Vivo Gene Transfer into the Adult Mammalian Brain: Polyethylenimine

1996 • 544 citations

Polylysine-based transfection systems utilizing receptor-mediated delivery

1998 • 506 citations

Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products

1995 • 471 citations

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery

1999 • 381 citations

Polyethylenimine-based intravenous delivery of transgenes to mouse lung

1998 • 367 citations

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

1997 • 363 citations

Polycation-based DNA complexes for tumor-targeted gene deliveryin vivo

1999 • 351 citations

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

2001 • 350 citations

Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold.

1996 • 348 citations

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand

1992 • 325 citations

Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system

1998 • 313 citations

Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse

2000 • 312 citations

Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI)

1999 • 280 citations

ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo

1997 • 253 citations

In Vivo Delivery to Tumors of DNA Complexed with Linear Polyethylenimine

1999 • 209 citations

Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs

2000 • 145 citations

Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes

2000 • 140 citations

Nonviral vectors for gene therapy

1999 • 139 citations

Obstacles and advances in non-viral gene delivery.

2000 • 48 citations

Ovarian carcinoma cells are effectively transfected by polyethylenimine (PEI) derivatives

2000 • 34 citations

Development of Transferrin-Polycation/DNA Based Vectors for Gene Delivery to Melanoma Cells

1999 • 34 citations

Polycation/DNA complexes for in vivo gene delivery

2000 • 29 citations

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