Randomized controlled trial of recombinant alpha-2a-interferon for chronic hepatitis C

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B Hepatitis

1989 • 3,401 citations

Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

1989 • 1,658 citations

Recombinant Interferon Alfa Therapy for Chronic Hepatitis C

1989 • 1,233 citations

Treatment of Chronic Non-A, Non-B Hepatitis with Recombinant Human Alpha Interferon

1986 • 980 citations

Detection of hepatitis C virus RNA by a two-stage polymerase chain reaction with two pairs of primers deduced from the 5'-noncoding region.

1990 • 548 citations

Non-A, non-B hepatitis. I. Recognition, epidemiology, and clinical features

1983 • 506 citations

Viral Hepatitis and Liver Disease

1988 • 445 citations

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.

1991 • 426 citations

New Light on Carcinoid Flush

1964 • 283 citations

Viral Hepatitis. 1981 International Symposium.

1983 • 264 citations

Sporadic Non-A, Non-B Hepatitis: Frequency and Epidemiology in an Urban U.S. Population

1982 • 224 citations

Neutralizing Antibodies to Interferon- : Relative Frequency in Patients Treated with Different Interferon Preparations

1991 • 214 citations

Long-term follow-up of acute and chronic non-A, non-B post-transfusion hepatitis: evidence of progression to liver cirrhosis.

1982 • 187 citations

Effects of Interferon on Antibody Synthesis in Vitro

1974 • 183 citations

Interferon-neutralizing antibodies in a patient treated with human fibroblast interferon

1981 • 156 citations

Non-A, Non-B Posttransfusion Hepatitis—A Decade Later

1985 • 131 citations

[74] Quantitation of neutralization of interferon by antibody

1986 • 127 citations

Randomised controlled trial of interferon alfa (lymphoblastoid interferon) in chronic non-A non-B hepatitis.

1989 • 125 citations

Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon alfa-2a by intramuscular injection

1987 • 121 citations

ALPHA-INTERFERON THERAPY FOR NON-A, NON-B HEPATITIS TRANSMITTED BY GAMMAGLOBULIN REPLACEMENT THERAPY

1987 • 119 citations

Interferon acts directly on human B lymphocytes to modulate immunoglobulin synthesis.

1981 • 114 citations

Low incidence of serum neutralizing factors in patients receiving recombinant alfa-2b interferon (intron a)

1986 • 102 citations

Interferon antibodies may negate the antiviral effects of recombinant α-interferon treatment in patients with chronic hepatitis B virus infection

1990 • 81 citations

Effect of interferon-alpha on immunoglobulin synthesis by human B cells.

1986 • 73 citations

A Randomized Controlled Open Study of Interferon Alpha-2b Treatment of Chronic IMon-A, Non-B Posttransfusion Hepatitis: No Correlation of Outcome to Presence of Hepatitis C Virus Antibodies

1989 • 73 citations

Treatment of Chronic Hepatitis B with Interferon: Experience in Western Countries

1989 • 69 citations

Treatment of chronic non‐A, non‐B hepatitis with acyclovir: Pilot study

1985 • 67 citations

Interferon antibodies in patients with chronic HBV infection treated with recombinant interferon

1989 • 65 citations

The detection of antibodies to recombinant interferon alfa-2a in human serum

1987 • 55 citations

Recombinant human alpha-interferon therapy for chronic non-A, non-B hepatitis: second report.

1990 • 38 citations

Anti-alpha interferon antibodies after alpha interferon treatment in patients with chronic viral hepatitis.

1988 • 20 citations

Treatment of posttransfusion non-A, non-B acute and chronic hepatitis with human fibroblast beta-interferon: a preliminary report.

1989 • 19 citations