Mutations of BRAF and KRAS Precede the Development of Ovarian Serous Borderline Tumors

Mutations of the BRAF gene in human cancer

2002 • 10,249 citations

RAS oncogenes: the first 30 years

2003 • 1,788 citations

High frequency of BRAF mutations in nevi

2002 • 1,701 citations

Digital PCR

1999 • 1,585 citations

Blaustein's Pathology of the Female Genital Tract

2019 • 1,317 citations

Ovarian Tumorigenesis

2004 • 1,182 citations

The Genetic Basis of Human Cancer

1997 • 1,113 citations

Mutations in BRAF and KRAS Characterize the Development of Low-Grade Ovarian Serous Carcinoma

2003 • 829 citations

Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

2003 • 808 citations

The Raf/MEK/ERK pathway: new concepts of activation

2001 • 716 citations

The Histologic Type and Stage Distribution of Ovarian Carcinomas of Surface Epithelial Origin

2003 • 523 citations

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.

2003 • 432 citations

Patterns of p53 Mutations Separate Ovarian Serous Borderline Tumors and Low- and High-grade Carcinomas and Provide Support for a New Model of Ovarian Carcinogenesis

2005 • 405 citations

Diverse Tumorigenic Pathways in Ovarian Serous Carcinoma

2002 • 345 citations

BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas.

2003 • 329 citations

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

2003 • 253 citations

In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low‐grade serous tumours

2004 • 233 citations

p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.

1993 • 216 citations

Incidence patterns of invasive and borderline ovarian tumors among white women and black women in the United States

2002 • 100 citations

Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma

2004 • 87 citations

Simple cyst in the postmenopausal patient: detection and management.

1998 • 85 citations

Genetic Disparity Between Morphologically Benign Cysts Contiguous to Ovarian Carcinomas and Solitary Cystadenomas

1995 • 77 citations

p53 mutations in ovarian tumors, detected by temperature‐gradient gel electrophoresis, direct sequencing and immunohistochemistry

1995 • 76 citations

Functional ovarian cysts in premenopausal and gynecologically healthy women

2002 • 73 citations

Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity

2002 • 72 citations

K-ras mutations in nonmucinous ovarian epithelial tumors: a molecular analysis and clinicopathologic study of 144 patients.

1998 • 71 citations

Molecular genetic analysis of ovarian serous cystadenomas

2004 • 57 citations

K-ras mutations in nonmucinous ovarian epithelial tumors

1998 • 51 citations

Advances from genetic clues in pancreatic cancer

1998 • 44 citations

Asymptomatic Postmenopausal Simple Ovarian Cyst

2002 • 27 citations