Potent inhibitory action of the gastric proton pump inhibitor lansoprazole against urease activity of Helicobacter pylori: unique action selective for H. pylori cells

Tissue sulfhydryl groups

1959 • 25,130 citations

UNIDENTIFIED CURVED BACILLI IN THE STOMACH OF PATIENTS WITH GASTRITIS AND PEPTIC ULCERATION

1984 • 5,344 citations

Campylobacter pylori and Peptic Ulcer Disease

1989 • 760 citations

Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity

1991 • 419 citations

Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate.

1986 • 368 citations

Purification and characterization of urease from Helicobacter pylori.

1990 • 351 citations

Campylobacter pylori and gastroduodenal disease

1990 • 303 citations

The mechanism of action of the antisecretory agent omeprazole

1986 • 303 citations

Characterization of urease from Campylobacter pylori

1988 • 293 citations

Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori

1991 • 280 citations

Purification and N-terminal analysis of urease from Helicobacter pylori

1990 • 250 citations

Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange

1992 • 239 citations

CAMPYLOBACTER PYLORIDIS, UREASE, HYDROGEN ION BACK DIFFUSION, AND GASTRIC ULCERS

1986 • 236 citations

Helicobacter pylori urease activity is toxic to human gastric epithelial cells

1990 • 235 citations

Campylobacter pyloridis and Gastritis

1986 • 232 citations

Topographic association between active gastritis and Campylobacter pylori colonisation.

1989 • 201 citations

Antisecretory and antiulcer activities of a novel proton pump inhibitor AG-1749 in dogs and rats.

1989 • 144 citations

Nucleotide sequence of two genes from Helicobacter pylori encoding for urease subunits

1990 • 138 citations

Evidence for acid-induced transformation of omeprazole into an active inhibitor of (H+ + K+)-ATPase within the parietal cell

1984 • 133 citations

Invvestigation of the structure and localizatioin of the urease of Helicobacter pylori using monoclonal antibodies

1990 • 117 citations

Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749.

1989 • 105 citations

Characteristics of Helicobacter pylori variants selected for urease deficiency

1992 • 84 citations

In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori)

1987 • 72 citations

Intracellular Vacuolization Caused by the Urease of Helicobacter pylori

1990 • 71 citations

Two-dimensional gel electrophoresis and immunoblotting of Campylobacter pylori proteins

1989 • 64 citations

Monoclonal antibodies against the native urease of Helicobacter pylori: synergistic inhibition of urease activity by monoclonal antibody combinations

1992 • 64 citations

Localization of omeprazole and metabolites in the mouse

1985 • 51 citations

Treatment failure of norfloxacin against Campylobacter pylori and chronic gastritis in patients with nonulcerative dyspepsia

1989 • 30 citations

Functional domains of the gastric HK ATPase

1989 • 29 citations

Binding site of omeprazole in hog gastric H+,K+-ATPase

1990 • 26 citations

Histological aspects of Campylobacter pylori colonisation and infection of gastric and duodenal mucosa.

1988 • 25 citations

Campylobacter pylori in Japan: Bacteriological feature and prevalence in healthy subjects and patients with gastroduodenal disorders

1989 • 25 citations

Pharmacokinetic, bacteriological and clinical aspects on the use of doxycycline in patients with active duodenal ulcer associated with Campylobacter pylori.

1988 • 19 citations

Enhanced clearing ofHelicobacter pyloriafter omeprazole plus roxithromycin treatment

1991 • 16 citations

Localization of a novel proton pump inhibitor, lansoprazole, in the gastric mucosa of the rat: A radioautographic study.

1992 • 6 citations