Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 • 1,680 citations

Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.

1984 • 529 citations

Thymoma production of T cell growth factor (Interleukin 2).

1980 • 487 citations

Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients

1989 • 349 citations

Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.

1987 • 289 citations

A reproducible microanalytical method for the detection of specific RNA sequences by dot-blot hybridization

1984 • 247 citations

UV crosslinking of RNA to nylon membrane enhances hybridization signals

1986 • 228 citations

Glutathione and the Hexose Monophosphate Shunt in Phagocytizing and Hydrogen Peroxide-treated Rat Leukocytes

1969 • 207 citations

Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro. Role of the mixed disulfide of 2-mercaptoethanol and cysteine.

1981 • 206 citations

Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase.

1989 • 164 citations

The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation.

1985 • 153 citations

Enhancement by Reducing Agents of the Transformation of Human and Rabbit Peripheral Lymphocytes

1970 • 141 citations

Glutathione Regulates Interleukin-2 Activity on Cytotoxic T-cells

1989 • 127 citations

Plasma Membrane and Cell Cortex Interactions in Lymphocyte Functions

1980 • 77 citations

Enhancement of intracellular glutathione promotes lymphocyte activation by mitogen

1986 • 76 citations

Identification of T cell lymphoma tumor antigens on human T cell lines

1976 • 74 citations

Inhibition of lectin-induced lymphocyte activation by 2-cyclohexene-1-one: decreased intracellular glutathione inhibits an early event in the activation sequence.

1981 • 70 citations

Activation of cytotoxic T lymphocytes requires at least two spleen cell-derived helper factors besides interleukin 2.

1983 • 56 citations

Regulation of T-cell functions by l-lactate

1987 • 47 citations

The synergistic action of the copper chelator bathocuproine sulphonate and cysteine in enhancing growth of L1210 cells in vitro

1985 • 45 citations

Immune‐interferon (IFN‐γ), Macrophage‐activating Factors (MAFs), and Colony‐stimulating Factors (CSFs) Secreted by T Cell Clones in Limiting Dilution Microcultures, Long‐term Cultures, and by T Cell Hybridomas

1983 • 43 citations

Endogenous copper is cytotoxic to a lymphoma in primary culture which requires thiols for growth

1985 • 23 citations