The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1977 • 683 citations

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

1982 • 345 citations

Anoxia and endothelium‐dependent reactivity of the canine femoral artery.

1983 • 259 citations

Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine

1983 • 249 citations

Regulation of arachidonic acid production: role of phospholipases C and A2

1982 • 239 citations

Inhibition of platelet secretion by an antagonist of intracellular calcium

1976 • 167 citations

Endothelial cells are involved in the vasodilatory response to hypoxia

1983 • 151 citations

Adenine Nucleotide and Adenosine Metabolism in Cultured Coronary Endothelial Cells: Formation and Release of Adenine Compounds and Possible Functional Implications

1983 • 118 citations

Vascular actinos of arachidonic acid and its metabolites in perfused mesenteric and femoral beds of the dog

1978 • 111 citations

Vasodilation of cat cerebral arterioles by prostaglandins D2, E2, G2, and I2

1979 • 108 citations

Metabolism of prostacyclin in blood vessels

1978 • 103 citations

Anoxia-induced release of prostaglandins in rabbit isolated hearts.

1975 • 92 citations

Hypoxia Causes Prostaglandin Release from Perfused Rabbit Hearts

1974 • 77 citations

The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels

1984 • 77 citations

Evidence for multiple metabolic pools of phosphatidylinositol in stimulated platelets.

1982 • 73 citations

The endothelium-dependent vasodilator effect of acetylcholine: Characterization of the endothelial relaxing factor with inhibitors of arachidonic acid metabolism

1984 • 73 citations

On the specificity of antisera against prostaglandins A₂ and E₂

1973 • 72 citations

Release of two vasodilators, adenosine and prostacyclin, from isolated rabbit hearts during controlled hypoxia.

1983 • 69 citations

Relationship between oxygen tension, coronary vasodilation and prostaglandin biosynthesis in the isolated rabbit heart

1975 • 67 citations

BRADYKININ‐INDUCED RELAXATION OF RENAL AND PULMONARY ARTERIES IS DEPENDENT UPON INTACT ENDOTHELIAL CELLS

1981 • 66 citations

The effect of hypoxia on prostaglandin output and on tone in isolated coronary arteries

1977 • 64 citations

Effect of cyanide on oxygen tension-dependent mechanical tension in rabbit aorta.

1979 • 61 citations

Oxygen requirement for prostaglandin biosynthesis

1978 • 51 citations

Prostacyclin (PGI2) mediates hypoxic relaxation of bovine coronary arterial strips

1981 • 39 citations

Acetylcholine stimulates the release of prostacyclin by rabbit aorta endothelium

1983 • 34 citations

Prostacyclin‐dependent coronary vasodilation in rabbit and guinea pig hearts

1979 • 32 citations

Formation and elimination of prostacyclin metabolites in the cat in vivo as determined by radioimmunoassay of unextracted plasma

1981 • 27 citations

Role of hypercapnic acidosis in the local regulation of blood flow in skeletal muscle.

1971 • 19 citations

Studies on the nature of a prostaglandin receptor in canine and rabbit vascular smooth muscle.

1976 • 18 citations

The stimulatory effect of prostacyclin (PGI2) on isolated rabbit and rat aorta is probably associated to the generation of a thromboxane A2 (TXA2) "like-material".

1983 • 17 citations

Prostaglandin mediated relaxation of coronary artery strips under hypoxia

1978 • 15 citations

CARDIAC PROSTACYCLIN RELEASE: STIMULATION BY HYPOXIA AND VARIOUS AGENTS

1979 • 15 citations

Instructions to Author

1971 • 11 citations

Effect of exogenous and endogenous prostacyclin on the contractility of rabbit splenic capsular smooth muscle

1980 • 7 citations

Effects of prostaglandins E2, I2 and F2 alpha on the tone of isolated coronary arteries from alloxan-diabetic dogs.

1982 • 6 citations

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