Selective retention of recombinant plasmids coding for human insulin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Experiments in molecular genetics

1972 • 28,260 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis

1975 • 1,135 citations

DNA Restriction Enzyme from E. coli

1968 • 816 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

pBR322 restriction map derived from the DNA sequence: accurate DNA size markers up to 4361 nucleotide pairs long

1978 • 768 citations

Positive selection for loss of tetracycline resistance

1980 • 704 citations

Selection for loss of tetracycline resistance by Escherichia coli

1981 • 585 citations

Mutations in a temperate bacteriophage affecting its ability to lysogenize Escherichia coli

1957 • 481 citations

Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures

1975 • 411 citations

Partitioning of bacterial plasmids during cell division: a cis-acting locus that accomplishes stable plasmid inheritance

1980 • 335 citations

A PERSPECTIVE ON THE APPLICATION OF GENETIC ENGINEERING: STABILITY OF RECOMBINANT PLASMID

1981 • 267 citations

[10] Elution of DNA from agarose gels after electrophoresis

1979 • 266 citations

Gene regulation at the right operator (OR) of bacteriophage λ

1980 • 243 citations

Transformation in Escherichia coli: cryogenic preservation of competent cells

1977 • 242 citations

Purified λ regulatory protein cII positively activates promoters for lysogenic development

1981 • 241 citations

Gene regulation at the right operator (OR) of bacteriophage λ

1980 • 241 citations

Precise location of two promoters for the beta-lactamase gene of pBR322. S1 mapping of ribonucleic acid isolated from Escherichia coli or synthesized in vitro.

1982 • 210 citations

Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal.

1981 • 177 citations

Genome Construction Between Bacterial Species In Vitro: Replication and Expression of Staphylococcus Plasmid Genes in Escherichia coli

1974 • 176 citations

The Maintenance of Plasmid-containing Organisms in Populations of Escherichia coli

1981 • 163 citations

Maintenance and genetic stability of vector plasmids pBR322 and pBR325 in Escherichia coli K12 strains grown in a chemostat

1981 • 141 citations

Deletions and insertions in the immunity region of coliphage lambda: Revised measurement of the promoter-startpoint distance

1974 • 129 citations

Maintenance of some ColE1-type plasmids in chemostat culture

1980 • 126 citations

A plasmid cloning vehicle allowing a positive selection for inserted fragments

1980 • 105 citations

Phenotypic Stability of trp Operon Recombinant Plasmids in Escherichia coli

1980 • 64 citations

Lethality of palindromic DNA and its use in selection of recombinant plasmids

1982 • 62 citations

Effect of strong promoters on the cloning in Escherichia coli of DNA fragments from Streptococcus pneumoniae

1982 • 58 citations

Use of Phage Immunity in Molecular Cloning Experiments

1977 • 22 citations

Novel selection for tetracycline- or chloramphenicol-sensitive Escherichia coli

1982 • 12 citations

Optimization of conditions for the in vitro formation of hybrid DNA molecules by DNA ligase

1979 • 4 citations