Agrin is a differentiation-inducing “stop signal” for motoneurons in vitro

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

Synaptic structure and development: The neuromuscular junction

1993 • 846 citations

Essential functions of synapsins I and II in synaptic vesicle regulation

1995 • 699 citations

Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin

1992 • 669 citations

The Agrin Hypothesis

1990 • 637 citations

Reinnervation of muscle fiber basal lamina after removal of myofibers. Differentiation of regenerating axons at original synaptic sites.

1978 • 577 citations

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction

1989 • 566 citations

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue.

1981 • 560 citations

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2

1995 • 447 citations

Structure and expression of a rat agrin

1991 • 310 citations

The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans

1993 • 305 citations

The agrin gene codes for a family of basal lamina proteins that differ in function and distribution

1992 • 252 citations

Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrices.

1986 • 240 citations

Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site.

1995 • 232 citations

RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes

1992 • 212 citations

cDNA that encodes active agrin

1992 • 199 citations

Developmental regulation of highly active alternatively spliced forms of agrin

1993 • 188 citations

Specificity of early motoneuron growth cone outgrowth in the chick embryo

1985 • 153 citations

Protein kinase C is involved in laminin stimulation of neurite outgrowth

1989 • 140 citations

A motoneuron-selective stop signal in the synaptic protein S-laminin

1995 • 136 citations

Functions of agrin and agrin-related proteins

1993 • 119 citations

Development of basal lamina in synaptic and extrasynaptic portions of embryonic rat muscle

1984 • 113 citations

Agrin mediates cell contact-induced acetylcholine receptor clustering

1991 • 113 citations

An LRE (leucine-arginine-glutamate)-dependent mechanism for adhesion of neurons to S-laminin

1991 • 111 citations

Agrin-related molecules are concentrated at acetylcholine receptor clusters in normal and aneural developing muscle.

1989 • 104 citations

Building synapses: agrin and dystroglycan stick together

1994 • 100 citations

The development of functional neuromuscular junctionsin vitro: An ultrastructural and physiological study

1980 • 85 citations

The expression and localization of synaptic vesicle antigens at neuromuscular junctions in vitro

1985 • 82 citations

Early appearance of and neuronal contribution to agrin-like molecules at embryonic frog nerve-muscle synapses formed in culture

1992 • 77 citations

Progressive restriction of synaptic vesicle protein to the nerve terminal during development of the neuromuscular junction

1989 • 74 citations

Cell-specific regulation of agrin RNA splicing in the chick ciliary ganglion

1994 • 74 citations

Basal lamina components are concentrated in premuscle masses and at early acetylcholine receptor clusters in chick embryo hindlimb muscles

1988 • 71 citations

Agrin and the molecular choreography of synapse formation

1993 • 69 citations

Analysis of proteoglycan expression in developing chicken brain: Characterization of a heparan sulfate proteoglycan that interacts with the neural cell adhesion molecule

1995 • 64 citations

Dystrophin-associated proteins and synapse formation: Is α-dystroglycan the agrin receptor?

1994 • 60 citations

Effects of antibodies to neural cell adhesion molecule (N-CAM) on the differentiation of neuromuscular contacts between ciliary ganglion neurons and myotubes in vitro

1987 • 54 citations

An electron-microscopic study of the de novo formation of neuromuscular junctions in tissue culture

1969 • 53 citations

Muscle agrin: neural regulation and localization at nerve-induced acetylcholine receptor clusters

1993 • 52 citations

Muscle-derived agrin in cultured myotubes: Expression in the basal lamina and at induced acetylcholine receptor clusters

1992 • 47 citations

Patterns of Presynaptic Gene Expression Define Two Stages of Synaptic Differentiation

1995 • 37 citations

A specific effect of muscle cells on the distribution of presynaptic proteins in neurites and its absence in a C2 muscle cell variant

1990 • 34 citations

Functional and non‐functional contacts between ciliary neurones and muscle grown in vitro.

1976 • 24 citations

Collagen synthesis inhibition reduces clustering of heparan sulfate proteoglycan and acetylcholine receptors but not agrin or p65, at neuromuscular contacts in vitro

1995 • 9 citations