Evidence‐based guidelines for the use of immunologic tests: Antinuclear antibody testing

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1980 • 4,703 citations

Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA)

1972 • 1,816 citations

A New Approach to the Classification of Idiopathic Inflammatory Myopathy

1991 • 959 citations

DECLINE IN SKELETAL MUSCLE MITOCHONDRIAL RESPIRATORY CHAIN FUNCTION: POSSIBLE FACTOR IN AGEING

1989 • 722 citations

Diversity of antinuclear antibodies in progressive systemic sclerosis

1980 • 520 citations

Raynaud's phenomenon

2001 • 416 citations

Systemic Lupus Erythematosus

1985 • 401 citations

The CREST syndrome: A distinct serologic entity with anticentromere antibodies

1980 • 369 citations

High prevalence of serological markers of autoimmunity in patients with chronic hepatitis C

1995 • 367 citations

Differentiation and characterization of autoantibodies and their antigens in sjögren's syndrome

1976 • 343 citations

Sjögren's Syndrome: Association of Anti-Ro(SS-A) Antibodies with Vasculitis, Hematologic Abnormalities, and Serologic Hyperreactivity

1983 • 311 citations

Different antibody patterns and different prognoses in patients with scleroderma with various extent of skin sclerosis.

1986 • 196 citations

Antinuclear, anticytoplasmic, and anti-Sjogren's Syndrome antigen A (SS-A/Ro) antibodies in female blood donors

1985 • 181 citations

Serological markers in progressive systemic sclerosis: clinical correlations.

1983 • 176 citations

A critical evaluation of enzyme immunoassays for detection of antinuclear autoantibodies of defined specificities: I. Precision, sensitivity, and specificity

1999 • 170 citations

Serum antinuclear antibodies in progressive systemic sclerosis (scleroderma)

1968 • 143 citations

Multiplicity of antibodies in myositis sera

1984 • 143 citations

Clinical significance of antinuclear antibodies. Comparison of detection with immunofluorescence and enzyme‐linked immunosorbent assays

1997 • 137 citations

The association of antinuclear antibodies with the chronic iridocyclitis of juvenile rheumatoid arthritis (Still's disease)

1974 • 133 citations

A prospective evaluation of 118 patients with the fibromyalgia syndrome: prevalence of Raynaud's phenomenon, sicca symptoms, ANA, low complement, and Ig deposition at the dermal-epidermal junction.

1986 • 131 citations

Primary Sjögren's syndrome in men

1986 • 118 citations

Antinuclear Antibody Induced by Procainamide

1969 • 118 citations

FAMILY STUDIES IN SYSTEMIC LUPUS ERYTHEMATOSUS.

1964 • 117 citations

Diversity of autoantibodies in primary biliary cirrhosis and chronic active hepatitis.

1984 • 111 citations

Antihistone antibodies in patients with localized scleroderma

1993 • 110 citations

Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in the (H2A-H2B)-DNA complex.

1992 • 104 citations

Evolution of primary raynaud's phenomenon (raynaud's disease) to connective tissue disease

1985 • 103 citations

Early Undifferentiated Connective Tissue Disease: III. Outcome and Prognostic Indicators in Early Scleroderma (Systemic Sclerosis)

1993 • 93 citations

The analysis of antinuclear and antinucleolar autoantibodies of scleroderma by radioimmunoprecipitation assays

1990 • 91 citations

Diagnosis of systemic lupus erythematosus.

2003 • 85 citations

Association between fluorescent antinuclear antibodies, capillary patterns, and clinical features in scleroderma spectrum disorders

1984 • 80 citations

Frequency and significance of antinuclear antibodies in multiple sclerosis

1997 • 79 citations

Systemic lupus erythematosus: predictors of its occurrence among a cohort of patients with early undifferentiated connective tissue disease: multivariate analyses and identification of risk factors.

1996 • 79 citations

Increasing titers and changing specificities of antinuclear antibodies in patients with chronic liver disease who develop hepatocellular carcinoma

1993 • 76 citations

Autoimmunity in 28 patients after allogeneic bone marrow transplantation: comparison with Sjögren syndrome and scleroderma

1987 • 75 citations

High-titer antinuclear antibodies, anti-SSA/Ro antibodies and anti-nuclear RNP antibodies in patients with idiopathic thrombocytopenic purpura.

1994 • 67 citations

Systemic involvement and immunologic findings in patients presenting with Raynaud's phenomenon

1980 • 67 citations

Age‐related antinuclear factors: Immunologic characteristics and associated clinical aspects

1967 • 62 citations

The evolution of Raynaud's phenomenon: a longterm prospective study.

1995 • 62 citations

Antinuclear Antibodies in Multiple Sclerosis

1982 • 61 citations

Antinuclear antibodies in patients on anticonvulsant therapy.

1972 • 59 citations

Early undifferentiated connective tissue disease. II. The frequency of circulating antinuclear antibodies in patients with early rheumatic diseases.

1991 • 58 citations

The clinical significance of titered antinuclear antibodies

1967 • 58 citations

The diagnostic value of several immunological tests for anti‐nuclear antibody in predicting the development of connective tissue disease in patients presenting with Raynaud's phenomenon

1989 • 57 citations

Guidelines for immunologic laboratory testing in the rheumatic diseases: An introduction

2002 • 57 citations

A comparison of the prevalence of autoantibodies in individuals with chronic hepatitis C and those with autoimmune hepatitis: the role of interferon in the development of autoimmune diseases.

1997 • 57 citations

ANTIBODIES IN THE FAMILIES OF THYROTOXIC PATIENTS

1967 • 56 citations

The effect of age on clinical and serological manifestations in unselected patients with systemic lupus erythematosus.

1988 • 56 citations

Clinical, serological, and HLA phenotype subsets in Sjögren's syndrome.

1989 • 56 citations

Discovery of the LE cell and its morphology.

1969 • 55 citations

Subgroups of primary Sjogren's syndrome. Sjogren's syndrome in male and paediatric Greek patients

1997 • 54 citations

Autoantibody tests in autoimmune thyroid disease: a case-control study.

1991 • 54 citations

SYSTEMIC LUPUS ERYTHEMATOSUS IN 61 ORIENTAL MALES. A STUDY OF CLINICAL AND LABORATORY MANIFESTATIONS

1994 • 53 citations

Anti-SSA/Ro and anti-SSB/La antibodies in serum and saliva of patients with Sjogren's syndrome

1993 • 52 citations

Development of antinuclear antibodies during acebutolol therapy

1979 • 51 citations

Prevalence of nonthyroid specific autoantibodies in autoimmune thyroid diseases.

1995 • 51 citations

Antinuclear antibodies in the relatives of patients with systemic sclerosis

1985 • 48 citations

Identification of antihistone antibodies in subsets of juvenile chronic arthritis.

1989 • 48 citations

Immunological detection of nucleic acids and antibodies to nucleic acids and nuclear antigens by counterimmunoelectrophoresis.

1974 • 47 citations

Anti-Scl-70 antibodies detected by immunoblotting in progressive systemic sclerosis: specificity and clinical correlations.

1989 • 43 citations

Antinuclear antibodies and connective tissue disease features in fibromyalgia syndrome: a controlled study.

1993 • 43 citations

Antinuclear Antibodies and Cardiovascular Drugs

1980 • 43 citations

Clinical and serologic features of patients with polymyositis or dermatomyositis.

1985 • 41 citations

Antibodies to histones H1 and H5 in sera of patients with juvenile rheumatoid arthritis.

1989 • 41 citations

REACTIVITY OF ANTINUCLEAR ANTIBODIES WITH HISTONES AND OTHER ANTIGENS IN JUVENILE RHEUMATOID ARTHRITIS

1989 • 41 citations

Clinical and serological comparison of 17 chronic progressive systemic sclerosis (PSS) and 17 CREST syndrome patients matched for sex, age, and disease duration.

1984 • 40 citations

Use of the HEp‐2 cell substrate in the detection of antinuclear antibodies in juvenile rheumatoid arthritis

1984 • 40 citations

Diversity of antinucelar antibody responses in hepatocellular carcinoma

1997 • 39 citations

Circulating immune complexes and antinuclear antibodies in juvenile rheumatoid arthritis

1977 • 39 citations

Fluorescent Antinuclear Antibodies and Anti-SS-A/Ro in Patients with Immune Thrombocytopenia Subsequently Developing Systemic Lupus Erythematosus

1985 • 39 citations

Antibodies to nuclear antigens in polymyositis: relationship to autoimmune 'overlap syndromes' and carcinoma.

1981 • 38 citations

Antinuclear antibodies in chronic psychotic patients treated with chlorpromazine

1975 • 38 citations

Significance of a Positive Antinuclear Antibody Test in a Pediatric Population

1983 • 38 citations

More Evidence of Distinctive Features of Mixed Connective Tissue Disease

1993 • 36 citations

Rheumatoid arthritis: anti-Ro antibodies define a non-HLA-DR4 associated clinicoserological cluster.

1993 • 36 citations

Antinuclear antibodies in the relatives and spouses of patients with systemic sclerosis.

1986 • 36 citations

Autoantibodies in juvenile dermatomyositis.

1990 • 35 citations

Clinical setting of patients with systemic sclerosis by serum autoantibodies

1997 • 35 citations

Correlation of smooth-muscle and nuclear antibodies in normal subjects.

1977 • 35 citations

Autoantibodies to chromatin components in juvenile rheumatoid arthritis

1993 • 32 citations

Occurrence of antiperinuclear, antikeratin, and anti-RA 33 antibodies in juvenile chronic arthritis.

1993 • 32 citations

Characterization of antinucleolar antibody reactivity in patients with systemic sclerosis and their relatives.

1997 • 32 citations

ANTIBODIES TO HISTONES H1 AND H5 IN SERA OF PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS

1989 • 32 citations

IMMUNOLOGIC PROFILE OF PATIENTS WITH FIBROMYALGIA1

1997 • 31 citations

Antibodies to Nuclear Antigens in Graves' Disease

1988 • 31 citations

Comparison of clinical and serologic markers in systemic lupus erythematosus and overlap syndrome: a review of 247 patients.

1983 • 30 citations

Antinuclear antibodies in patients with chronic idiopathic autoimmune thrombocytopenia followed 2–30 years

1989 • 29 citations

Antibodies to extractable nuclear antigens. Has technological drift affected clinical interpretation?

2001 • 29 citations

Relation of titred peripheral pattern ANA to anti-DNA and disease activity in systemic lupus erythematosus.

1977 • 27 citations

Diagnostic and prognostic significance of different antinuclear antibodies in more than 1000 consecutive Albanian patients with rheumatic diseases.

1992 • 27 citations

Autoantibodies in juvenile arthritis

1984 • 26 citations

Follow-up of 151 patients with high-titer U1RNP antibodies

1996 • 26 citations

Autoantibodies in chronic arthritis of childhood: relations with each other and with histocompatibility antigens.

1992 • 25 citations

The frequency of antinuclear antibody (ANA) in children by use of mouse kidney (MK) and human epithelial cells (HEp-2) as substrates

1988 • 25 citations

Specificity, sensitivity and diagnostic predictive value of selected laboratory generated autoantibody profiles in patients with connective tissue diseases.

1991 • 23 citations

Serological profiles in the connective tissue diseases in Zimbabwean patients.

1989 • 22 citations

Antinuclear antibodies in routine analysis: the relevance of putative clinical associations.

1993 • 22 citations

IMMUNOLOGIC PARAMETERS IN SYSTEMIC SCLEROSIS

1994 • 22 citations

ANINUCLEAR ANTIBODIES IN EARLY ONSET PAUCIARTICULAR JUVENILE CHRONIC ARTHRITIS (JCA) ARE ASSOCIATED WITH HLA-DQB1^*0603: A POSSIBLE JCA-ASSOCIATED HUMAN LEUCOCYTE ANTIGEN HAPLOTIYPE

1995 • 22 citations

Connective tissue disease in southeast Georgia. A community based study of immunogenetic markers and autoantibodies.

1990 • 22 citations

Antinuclear antibodies in patients with scleroderma (systemic sclerosis) and in their blood relatives and spouses.

1993 • 21 citations

Significance of nuclear immunofluorescent patterns.

1969 • 21 citations

Autoantibodies in Greek juvenile chronic arthritis patients.

1991 • 21 citations

Autoantibodies and immunogenetics in 30 patients with systemic sclerosis and their families.

1987 • 21 citations

Studies of antinuclear antibodies in rheumatoid arthritis.

1982 • 20 citations

Anti-IgG and Antinuclear Antibodies in Juvenile Rheumatoid Arthritis

1972 • 19 citations

Antinuclear antibody profile in juvenile rheumatoid arthritis.

1991 • 19 citations

Clinical Significance of Antinuclear Antibodies in Japanese Patients with Systemic Sclerosis

1990 • 19 citations

Fluctuations in anti-nRNP levels in patients with mixed connective tissue disease are related to disease activity as part of a polyclonal B cell response.

1986 • 19 citations

Antinuclear Antibodies and Propylthiouracil Therapy

1972 • 18 citations

Antibodies to a 15 kD nuclear antigen in patients with juvenile chronic arthritis and uveitis.

1992 • 17 citations

Early Detection of Scleroderma Spectrum Disorders in Patients with Raynaud’s Phenomenon

1991 • 17 citations

Reduced T lymphoid colony growth in patients with progressive systemic sclerosis and rheumatoid arthritis.

1982 • 17 citations

Antinuclear antibody positivity in pediatric patients with autoimmune thyroid disease.

1997 • 16 citations

Detection of antinuclear antibody in the serum of patients with multiple sclerosis

1982 • 14 citations

Diagnosis of Systemic Lupus Erythematosus

1975 • 13 citations

Antinuclear antibodies and histocompatibility antigens in patients on long-term lithium therapy

1981 • 12 citations

Prevalence of nonthyroid specific autoantibodies in autoimmune thyroid diseases

1995 • 12 citations

IV. Presence of antinuclear factors (ANFs) in the total populations of relatives and spouses, and the correlation to rheumatic disease

1972 • 11 citations

Clinical differences between ANA/anti-ENA positive or negative primary Sjögren's syndrome

1992 • 10 citations

ANTINUCLEAR ANTIBODIES IN FIRST-DEGREE RELATIVES OF PATIENTS WITH POLYMYOSITIS-DERMATOMYOSITIS: ANALYSIS OF THE RELATIONSHIP WITH HLA HAPLOTYPES

1991 • 10 citations

Isolated Raynaud's phenomenon--a benign disorder.

1987 • 10 citations

Immunoreactivity to Nuclear Antigens in Systemic Lupus Erythematosus with or without Nephritis, and in Other Connective Tissue Diseases, with Particular Reference to the RNA-Protein Antigen

1977 • 9 citations

Sjogren's syndrome in Israel: Primary versus secondary disease

1994 • 9 citations

The significance of IgM antinuclear antibody in rheumatoid arthritis and other connective tissue diseases

1984 • 9 citations

Serologic Studies in Patients With Keratoconjunctivitis Sicca

1981 • 9 citations

Antinuclear antibodies in scleroderma, mixed connective tissue disease and “primary” Raynaud's phenomenon

1988 • 9 citations

CIinicaI Significance of Antibodies against Nuclear Antigens as Determined by lmmunoblotting

1985 • 8 citations

Serological profile of rheumatoid arthritis in West Africa

1992 • 7 citations

Antinuclear antibodies in arthritic and nonarthritic children with uveitis.

1990 • 7 citations

Studies on associations of antinuclear antibodies with antibodies to an uveitogenic peptide of retinal S antigen in children with uveitis.

1996 • 6 citations

The Prevalence of Autoantibodies in Symptomatic and Asymptomatic Patients with Breast Implants and Patients with Fibromyalgia

1996 • 6 citations

Autoimmunity in 28 patients after allogeneic bone marrow transplantation: comparison with Sjögren syndrome and scleroderma

1987 • 5 citations

Antinuclear antibodies in lupus erythematosus and Sjögren's syndrome: Clinical and immunological investigations

1988 • 5 citations

Influence of prazosin on the development of antinuclear antibodies in hypertensive patients

1979 • 5 citations

Value of test for antinuclear antibodies in rheumatic diseases.

1984 • 3 citations

Antinuclear antibodies and propylthiouracil therapy

1972 • 2 citations

Deleted Work

1955 • 0 citations