Characterization of [3H]paroxetine binding to rat cortical membranes

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Neurotransmitter receptor binding

1978 • 822 citations

On the Evaluation of the Constants V _m and K _M in Enzyme Reactions

1952 • 746 citations

Citalopram — Pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity

1982 • 589 citations

High-Affinity [ ³ H]Imipramine Binding in Rat Hypothalamus: Association with Uptake of Serotonin But Not of Norepinephrine

1980 • 378 citations

Specific tricyclic antidepressant binding sites in rat brain

1979 • 266 citations

Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

1979 • 259 citations

Demonstration of specific high affinity binding sites for [3H] imipramine in human brain

1980 • 258 citations

Specific tricyclic antidepressant binding sites in rat brain characterised by high-affinity 3H-imipramine binding

1980 • 249 citations

Demonstration of specific “high affinity” binding sites for [3H] imipramine on human platelets

1980 • 198 citations

Specific 3H-imipramine binding in human platelets

1980 • 183 citations

Does high affinity [3H] imipramine binding label serotonin reuptake sites in brain and platelet?

1981 • 163 citations

Localisation of Tricyclic Antidepressant Binding Sites on Serotonin Nerve Terminals

1981 • 151 citations

Complex Inhibition of [³H]Imipramine Binding by Serotonin and Nontricyclic Serotonin Uptake Blockers

1983 • 146 citations

High affinity binding of [3H]paroxetine and [3H]imipramine to human platelet membranes

1983 • 145 citations

Mechanism of imipramine inhibition of platelet 5-hydroxytryptamine transport.

1979 • 139 citations

Different Synaptic Location of Mianserin and Imipramine Binding Sites

1982 • 120 citations

Determination of 5-hydroxytryptophan, serotonin and 5-hydroxyindoleacetic acid in rat and human brain and biological fluids by reversed-phase high-performance liquid chromatography with electrochemical detection

1981 • 102 citations

Multiple benzodiazepine receptors

1980 • 101 citations

Potent and long-lasting potentiation of two 5-hydroxytryptophan-induced effects in mice by three selective 5-HT uptake inhibitors

1978 • 98 citations

Regional distribution of [3H]imipramine binding in rat brain

1981 • 96 citations

“Specific” Binding of [³H]Imipramine to Protease‐Sensitive and Protease‐Resistant Sites

1985 • 87 citations

Differentiation of two components of specific [3H]imipramine binding in rat brain

1984 • 76 citations

High‐ and Low‐Affinity Binding of [³H]Imipramine in Mouse Cerebral Cortex

1983 • 67 citations

Tryptamine, a Substrate for the Serotonin Transporter in Human Platelets, Modifies the Dissociation Kinetics of [³H]Imipramine Binding: Possible Allosteric Interaction

1985 • 65 citations

3H-imipramine binding sites in the rat brain

1981 • 61 citations

Size determination of binding polymers for [3H]imipramine and [3H]paroxetine in human platelet membranes

1984 • 48 citations

Multiple benzodiazepine receptors

1980 • 44 citations

Autoradiographic localization of [3H]-imipramine binding sites: Association with serotonergic neurons

1983 • 40 citations

Binding of [3H]Ro 11-2465. Possible identification of a subclass of [3H]imipramine binding sites.

1983 • 36 citations

Inhibitory effect of clomipramine and related drugs on serotonin uptake in platelets: More complicated than previously thought

1979 • 36 citations

[3H]Impramine binding in subcellular fractions of rat cerebral cortex after chemical lesion of serotonergic neurons

1983 • 32 citations

Saturable uptake of [3H]-tryptamine in rabbit platelets is inhibited by 5-hydroxytryptamine uptake blockers

1984 • 22 citations

Temperature-sensitive reversible loss of [3H]imipramine binding sites: Evidence suggesting different conformational states

1983 • 18 citations

Thermodynamics of the interactions of tricyclic drugs with binding sites for [3H]imipramine in mouse cerebral cortex

1984 • 18 citations

Specific high affinity [3H]imipramine binding sites in rat lung are associated with a non-neuronal uptake site for serotonin

1983 • 13 citations