Pharmacokinetic Effects of Vigabatrin on Cerebrospinal Fluid Amino Acids in Humans

γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE¹

1977 • 472 citations

Audiogenic seizure protection by elevated brain GABA concentration in mice: Effects of γ-acetylenic GABA and γ-vinyl GABA, two irreversible GABA-T inhibitors

1977 • 203 citations

DOUBLE-BLIND STUDY OF γ-VINYL GABA IN PATIENTS WITH REFRACTORY EPILEPSY

1984 • 197 citations

The relationship between GABA concentrations in brain and cerebrospinal fluid

1979 • 187 citations

Vigabatrin for refractory complex partial seizures

1987 • 176 citations

γ‐Vinyl GABA: A double‐blind placebo‐controlled trial in partial epilepsy

1985 • 166 citations

Double-blind Study of Vigabatrin in the Treatment of Drug-Resistant Epilepsy

1987 • 144 citations

Double‐Blind, Placebo‐Controlled Study of Vigabatrin (Gamma‐Vinyl GABA) in Drug‐Resistant Epilepsy

1986 • 142 citations

Vigabatrin in the Treatment of Epilepsy: A Double‐Blind, Placebo‐Controlled Study

1986 • 125 citations

Gamma-vinyl-GABA: A single-blind trial in patients with epilepsy

1983 • 98 citations

The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients.

1989 • 93 citations

Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, ?-acetylenic GABA (4-amino-hex-5-ynoic acid) and ?-vinyl GABA (4-amino-hex-5-enoic acid)

1978 • 86 citations

Effects of single doses of vigabatrin on CSF concentrations of GABA, homocarnosine, homovanillic acid and 5-hydroxyindoleacetic acid in patients with complex partial epilepsy

1988 • 78 citations

Double‐Blind Dose Reduction Study of Vigabatrin in Complex Partial Epilepsy

1987 • 69 citations