Foxo1 mediates insulin action on apoC-III and triglyceride metabolism

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1999 • 1,102 citations

Phosphorylation of the Transcription Factor Forkhead Family Member FKHR by Protein Kinase B

1999 • 719 citations

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

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Hypertriglyceridemia as a Result of Human apo CII Gene Expression in Transgenic Mice

1990 • 540 citations

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

2001 • 517 citations

Insulin Stimulates Phosphorylation of the Forkhead Transcription Factor FKHR on Serine 253 through a Wortmannin-sensitive Pathway

1999 • 470 citations

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth

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Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III.

1985 • 422 citations

Identification of a Sequence in the PEPCK Gene That Mediates a Negative Effect of Insulin on Transcription

1990 • 369 citations

The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants.

1995 • 339 citations

Regulation of Glucose-6-phosphatase Gene Expression by Protein Kinase Bα and the Forkhead Transcription Factor FKHR

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Targeted disruption of the apolipoprotein C-III gene in mice results in hypotriglyceridemia and protection from postprandial hypertriglyceridemia.

1994 • 315 citations

Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver.

1985 • 315 citations

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2001 • 292 citations

Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling

1999 • 289 citations

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

2000 • 273 citations

Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia.

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Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

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Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice

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Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes.

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FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter*

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Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice

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Human apolipoprotein A-I--C-III gene complex is located on chromosome 11.

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Triglycerides, apo C3 and Lp B:C3 and cardiovascular risk in Type II diabetes

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Insulin Regulation of Gene Expression through the Forkhead Transcription Factor Foxo1 (Fkhr) Requires Kinases Distinct from Akt

2001 • 81 citations

Inhibitory Effects of Specific Apolipoprotein C-III Isoforms on the Binding of Triglyceride-rich Lipoproteins to the Lipolysis-stimulated Receptor

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Association of plasma lipids and apolipoproteins with the insulin response element in the apoC-III promoter region in familial combined hyperlipidemia

1999 • 49 citations

FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter

1999 • 40 citations

Genetic heterogeneity in the apolipoprotein C-III promoter and effects of insulin

2001 • 29 citations

Apoprotein C-III deficiency markedly stimulates triglyceride secretion in vivo: comparison with apoprotein E

2001 • 22 citations