Proteinase inhibitors protect Leishmania amazonensis amastigotes from destruction by amino acid esters

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

1987 • 3,809 citations

[59] Inhibitors of lysosomal function

1983 • 331 citations

Low-Molecular-Weight Enzyme Inhibitors of Microbial Origin

1982 • 206 citations

Accumulation of amino acids by lysosomes incubated with amino acid methyl esters.

1979 • 137 citations

Two high affinity nucleoside transporters in Leishmania donovani

1987 • 126 citations

Differential effects of proteinase inhibitors and amines on the lysosomal and non-lysosomal pathways of protein degradation in isolated rat hepatocytes

1980 • 114 citations

Rupture of rat liver lysosomes mediated by l-amino acid esters

1973 • 108 citations

Leishmania mexicana: Amastigote hydrolases in unusual lysosomes

1986 • 105 citations

Three dimensional structure of the leishmania amastigote as revealed by computer-aided reconstruction from serial sections

1986 • 70 citations

Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters.

1986 • 70 citations

Purification and Characterization of Proteolytic Enzymes of Leishmania mexicana mexicana Amastigotes and Promastigotes

1984 • 69 citations

Characterization of carrier-mediated transport systems for small neutral amino acids in human fibroblast lysosomes.

1987 • 65 citations

ATP stimulates amino acid accumulation by lysosomes incubated with amino acid methyl esters. Evidence for a lysosomal proton pump.

1981 • 65 citations

Proteinases of Leishmania mexicana amastigotes and promastigotes: Analysis by gel electrophoresis

1981 • 64 citations

Patterns of amino acid efflux from isolated normal and cystinotic human leucocyte lysosomes.

1982 • 49 citations

Inhibition of Leishmania amastigote growth by antipain and leupeptin

1984 • 48 citations

Proteinase inhibitors as antileishmanial agents

1982 • 35 citations

Biochemical taxonomy of Leishmania

1973 • 33 citations

Leishmania mexicana: Destruction of Isolated Amastigotes by Amino Acid Esters

1987 • 28 citations

Synthetic analogues of the proteinase inhibitor: chymostatin

1984 • 20 citations

Destruction ofLeishmania mexicana amazonensis amastigotesby leucine methyl ester: protection by other amino acid esters

1987 • 19 citations

The effect of analogues of chymostatin on lysosomal and non-lysosomal components of protein degradation in isolated hepatocytes☆

1987 • 7 citations

The effect of synthetic analogues of chymostatin upon protein degradation in isolated skeletal muscle

1985 • 7 citations