Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells

Prognostic Factors in High-Grade Osteosarcoma of the Extremities or Trunk: An Analysis of 1,702 Patients Treated on Neoadjuvant Cooperative Osteosarcoma Study Group Protocols

2002 • 1,809 citations

Prognostic Factors in High-Grade Osteosarcoma of the Extremities or Trunk: An Analysis of 1,702 Patients Treated on Neoadjuvant Cooperative Osteosarcoma Study Group Protocols

2002 • 1,609 citations

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

1991 • 1,013 citations

Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.

2000 • 570 citations

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1999 • 441 citations

Chondrosarcoma of Bone.

1943 • 422 citations

Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Bone Metastases

2002 • 367 citations

Bisphosphonate treatment inhibits the growth of prostate cancer cells.

2001 • 345 citations

Antitumor effects of bisphosphonates

2003 • 310 citations

Treatment of Ewing sarcoma family of tumors: Current status and outlook for the future

2003 • 193 citations

Cultured Autologous Human Cells for Hard Tissue Regeneration: Preparation and Characterization of Mesenchymal Stem Cells from Bone Marrow

2004 • 172 citations

Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line

2001 • 152 citations

Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.

1993 • 138 citations

Chondrosarcoma of Bone

2001 • 122 citations

The anti-tumour activity of bisphosphonates

2002 • 117 citations

Early features of apoptosis detected by four different flow cytometry assays.

1998 • 113 citations

A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation

1998 • 100 citations

The bisphosphonate pamidronate is a potent inhibitor of Ewing??s sarcoma cell growth in vitro

2003 • 85 citations

The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro

2001 • 71 citations

Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis

2003 • 69 citations

Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway

2003 • 53 citations

Combined therapy with a new bisphosphonate, minodronate (YM529), and chemotherapy for multiple organ metastases of small cell lung cancer cells in severe combined immunodeficient mice.

2003 • 37 citations

p53‐R175H mutant gains new function in regulation of doxorubicin‐induced apoptosis

2004 • 31 citations

Apoptosis-Inducing Effect of a New Bisphosphonate, YM529, on Various Hematopoietic Tumor Cell Lines.

2003 • 24 citations

The anti-leukemic efficacy of the third generation bisphosphonate ONO5920/YM529

2005 • 16 citations