Structure of a dinucleoside phosphate–drug complex as model for nucleic acid–drug interaction

Structural considerations in the interaction of DNA and acridines

1961 • 2,199 citations

General Nature of the Genetic Code for Proteins

1961 • 1,347 citations

Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalation

1970 • 780 citations

The interaction of aminoacridines with nucleic acids

1956 • 529 citations

The degree of unwinding of the DNA helix by ethidium

1974 • 440 citations

The Biochemistry of Mutagenesis

1976 • 421 citations

RNA double-helical fragments at atomic resolution: II. The crystal structure of sodium guanylyl-3′,5′-cytidine nonahydrate

1976 • 374 citations

RNA double-helical fragments at atomic resolution: I. The crystal and molecular structure of sodium adenylyl-3′,5′-uridine hexahydrate

1976 • 361 citations

Acridine mutagens and DNA structure

1964 • 358 citations

Relaxation studies of the proflavine-DNA complex: The kinetics of an intercalation reaction

1969 • 284 citations

A Molecular Model for the Interaction of Ethidium Bromide with Deoxyribonucleic Acid

1964 • 236 citations

Structures of synthetic polynucleotides in the A-RNA and A′-RNA conformations: X-ray diffraction analyses of the molecular conformations of polyadenylic acid · polyuridylic acid and polyinosinic acid · polycytidylic acid

1973 • 225 citations

Crystal structure of a naturally occurring dinucleoside phosphate: Uridylyl 3′,5′-adenosine phosphate model for RNA chain folding

1972 • 172 citations

X-ray crystallographic visualization of drug-nucleic acid intercalative binding: structure of an ethidium-dinucleoside monophosphate crystalline complex, Ethidium: 5-iodouridylyl (3'-5') adenosine.

1975 • 155 citations

Organization of DNA in chromatin.

1976 • 153 citations

Kinetic and hydrodynamic studies of the complex of proflavine with poly A·poly U

1971 • 149 citations

FRAMESHIFT MUTATIONS

1974 • 135 citations

X-ray fiber diffraction evidence for neighbor exclusion binding of a platinum metallointercalation reagent to DNA.

1975 • 132 citations

The interaction of acridine dyes with DNA: An X-ray diffraction and optical investigation

1966 • 125 citations

Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.

1977 • 97 citations

Visualization of planar drug intercalations in B-DNA

1975 • 72 citations

Effect of DNA base composition on the intercalation of proflavine

1975 • 39 citations

Structure of guanylyl‐3′,5′‐cytidine monophosphate. II. Description of the molecular and crystal structure of the calcium derivative in space group P2₁

1975 • 26 citations

Proflavine dichloride dihydrate (3,6-diaminoacridine dihydrochloride dihydrate)

1974 • 20 citations

Crystal structure of proflavine, a DNA binding agent

1975 • 15 citations

The crystal and molecular structure of proflavine hemisulphate hydrate

1975 • 14 citations