The Role of the Active Site Cysteine in Catalysis by Type 1 Iodothyronine Deiodinase*

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

Type I iodothyronine deiodinase is a selenocysteine-containing enzyme

1991 • 884 citations

Molecular biological and biochemical characterization of the human type 2 selenodeiodinase.

1996 • 259 citations

Iodothyronine 5′-Deiodinase from Rat Kidney: Substrate Specificity and the 5′-Deiodination of Reverse Triiodothyr onine *

1980 • 231 citations

Cloning of a cDNA for the Type II Iodothyronine Deiodinase

1995 • 212 citations

Cloning and Expression of a cDNA for a Mammalian Type III Iodothyronine Deiodinase

1995 • 200 citations

Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase

1991 • 200 citations

Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme.

1995 • 190 citations

Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected β type thyroid hormone receptor

1989 • 177 citations

The Formation of Diselenide Bridges in Proteins by Incorporation of Selenocysteine Residues: Biosynthesis and Characterization of (Se)2-Thioredoxin

1994 • 176 citations

Nutritional and Hormonal Regulation of Thyroid Hormone Deiodinases

1995 • 160 citations

Thyroxine 5′-Deiodinase Activity of Rat Kidney: Observations on Activation by Thiols and Inhibition by Propylthiouracil*

1978 • 150 citations

Synthesis and Some Properties of Sulfate Esters and Sulfamates of Iodothyronines*

1985 • 136 citations

Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation

1992 • 113 citations

Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase.

1992 • 111 citations

Sulfhydryl Groups and the Monodeiodination of Thyroxine to Triiodothyronine

1978 • 111 citations

Selenocysteine insertion or termination: factors affecting UGA codon fate and complementary anticodon:codon mutations

1994 • 109 citations

Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency.

1995 • 77 citations

Activation and inactivation of thyroid hormone by type I iodothyronine deiodinase

1994 • 76 citations

The type III 5-deiodinase in Rana catesbeiana tadpoles is encoded by a thyroid hormone-responsive gene.

1995 • 64 citations

Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes.

1994 • 60 citations

Identification of essential histidine residues in rat type I iodothyronine deiodinase.

1992 • 56 citations

Affinity labeling of rat liver and kidney type I 5'-deiodinase. Identification of the 27-kDa substrate binding subunit.

1990 • 54 citations

Characterization of Essential Enzyme Sulfhydryl Groups of Thyroxine 5′-Deiodinase from Rat Kidney*

1980 • 54 citations

Structure-Activity Relationships for Thyroid Hormone Deiodination by Mammalian Type I Iodothyronine Deiodinases¹

1997 • 53 citations

The cDNA for the type I iodothyronine 5‘-deiodinase encodes an enzyme manifesting both high Km and low Km activity. Evidence that rat liver and kidney contain a single enzyme which converts thyroxine to 3,5,3‘-triiodothyronine.

1992 • 53 citations

Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromoacetyl-3,3′,5-triiodothyronine

1984 • 48 citations

RAPID DEIODINATION OF TRIIODOTHYRONINE SULFATE BY RAT LIVER MICROSOMAL FRACTION

1983 • 47 citations

Effects of Glutathione on Iodothyronine 5′-Deiodinase Activity*

1988 • 38 citations

Stimulation of Iodothyronine Outer Ring Monodeiodinase by Dihydrolipoamide*

1983 • 31 citations

Modulating Effect of Glutathione Disulfide on Thyroxine-5'-Deiodination by Rat Hepatocytes in Primary Culture: Effect of Glucose*

1983 • 21 citations

Type I Iodothyronine Deiodinase: Unexpected Complexities in a Simple Deiodination Reaction

1994 • 11 citations