Composite replicas: Methodologies for direct evaluation of the relationship between intramembrane and extramembrane structures

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.

1979 • 1,408 citations

FINE STRUCTURE IN FROZEN-ETCHED YEAST CELLS

1963 • 1,342 citations

Fracture faces of frozen membranes.

1966 • 745 citations

MEMBRANE SPLITTING IN FREEZE-ETCHING

1970 • 573 citations

Advances in ultrarapid freezing for the preservation of cellular ultrastructure

1986 • 432 citations

Organization of acetylcholine receptors in quick-frozen, deep-etched, and rotary-replicated Torpedo postsynaptic membrane.

1979 • 429 citations

ELECTRON MICROSCOPY OF STRUCTURAL DETAIL IN FROZEN BIOLOGICAL SPECIMENS

1957 • 426 citations

A NEW FREEZING-ULTRAMICROTOME

1961 • 407 citations

ADH ACTION: EVIDENCE FOR A MEMBRANE SHUTTLE MECHANISM*

1981 • 291 citations

Preparation and Properties of Phospholipid Bilayers Containing Rhodopsin

1972 • 252 citations

Membrane associated particles: Distribution in frog urinary bladder epithelium at rest and after oxytocin treatment

1974 • 249 citations

Procedure for freeze-drying molecules adsorbed to mica flakes

1983 • 222 citations

Freeze Fracture: Methods, Artifacts, and Interpretations

1979 • 210 citations

Label-fracture: a method for high resolution labeling of cell surfaces.

1984 • 120 citations

Pitfalls of immunogold labeling: analysis by light microscopy, transmission electron microscopy, and photoelectron microscopy.

1987 • 118 citations

The use of propane/isopentane mixtures for rapid freezing of biological specimens

1981 • 112 citations

Interaction of a hydrophobic protein with liposomes evidence for particles seen in freeze fracture as being proteins

1974 • 109 citations

Liquid nitrogen‐based quick freezing: Experiences with bounce‐free delivery of cholinergic nerve terminals to a metal surface

1984 • 103 citations

Membrane structural and functional responses to vasopressin in toad bladder

1976 • 71 citations

Freeze-fracture techniques and applications to the structural analysis of the mammalian plasma membrane

1977 • 66 citations

Simple procedures for evaluating the cryofixation of biological samples

1982 • 66 citations

Cytoplasmic involvement in ADH-mediated osmosis across toad urinary bladder

1983 • 46 citations

Postreplication labeling of E‐leaflet molecules: Membrane immunoglobulins localized in sectioned, labeled replicas examined by TEM and HVEM

1987 • 40 citations

Labelled‐replica techniques: post‐shadow labelling of intramembrane particles in freeze‐fracture replicas

1982 • 39 citations

Visualization of endocytosed markers in freeze-fracture studies of toad urinary bladder.

1987 • 36 citations

Fluorescent markers to study membrane retrieval in antidiuretic hormone-treated toad urinary bladder

1986 • 31 citations

Detection of surface-bound ligands by freeze-fracture autoradiography.

1985 • 18 citations

Evaluation of granule exocytosis in toad urinary bladder

1986 • 16 citations

Vasopressin-induced changes in the three-dimensional structure of toad bladder apical surface

1987 • 15 citations

Structural and cytochemical differentiation of membrane elements of the apical membrane of amphibian urinary bladder epithelial cells. A label fracture study

1985 • 12 citations

Direct visualization of the interrelationship between intramembrane and extracellular structures.

1989 • 11 citations

Interactions of lectins with specific cell types in toad urinary bladder. Surface distribution revealed by colloidal gold probes and label fracture.

1986 • 11 citations