Diagnosis of cobalamin deficiency I: Usefulness of serum methylmalonic acid and total homocysteine concentrations

Neuropsychiatric Disorders Caused by Cobalamin Deficiency in the Absence of Anemia or Macrocytosis

1988 • 1,306 citations

Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.

1988 • 479 citations

Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations

1990 • 465 citations

Homocysteinemia due to folate deficiency

1987 • 423 citations

Quantitation of total homocysteine, total cysteine, and methionine in normal serum and urine using capillary gas chromatography-mass spectrometry

1987 • 291 citations

Cobalamin Analogues Are Present in Human Plasma and Can Mask Cobalamin Deficiency because Current Radioisotope Dilution Assays Are Not Specific for True Cobalamin

1978 • 262 citations

The Megaloblastic Anaemias

1980 • 258 citations

Higher total plasma homocysteine in vitamin B12 deficiency than in heterozygosity for homocystinuria due to cystathionine β-synthase deficiency

1988 • 227 citations

METHYLMALONIC ACID EXCRETION: AN INDEX OF VITAMIN-B12 DEFICIENCY

1962 • 225 citations

Fully automated fluorescence assay for determining total homocysteine in plasma.

1989 • 208 citations

Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.

1986 • 181 citations

Solid-phase sample extraction for rapid determination of methylmalonic acid in serum and urine by a stable-isotope-dilution method.

1989 • 177 citations

Pernicious anemia. The expected findings of very low serum cobalamin levels, anemia, and macrocytosis are often lacking

1988 • 171 citations

Impaired assimilation of egg Co 57 vitamin B 12 in patients with hypochlorhydria and achlorhydria and after gastric resection.

1973 • 136 citations

Food Cobalamin Malabsorption Occurs Frequently in Patients With Unexplained Low Serum Cobalamin Levels

1988 • 135 citations

Pernicious Anemia

1988 • 125 citations

Impaired Assimilation of EGG CO57 Vitamin B12 in Patients With Hypochlorhydria and Achlorhydria and After Gastric Resection

1973 • 122 citations

Clinically significant vitamin B12 deficiency secondary to malabsorption of protein-bound vitamin B12

1979 • 115 citations

Quantitation of methylmalonic acid and other dicarboxylic acids in normal serum and urine using capillary gas chromatography-mass spectrometry

1985 • 109 citations

STUDIES ON THE RELATIONSHIPS OF VITAMIN B12, FOLIC ACID, THYMINE, URACIL, AND METHYL GROUP DONORS IN PERSONS WITH PERNICIOUS ANEMIA AND RELATED MEGALOBLASTIC ANEMIAS

1950 • 107 citations

Determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection

1989 • 100 citations

Evidence That Some Patients with Pernicious Anemia Are Not Recognized by Radiodilution Assay for Cobalamin in Serum

1978 • 86 citations

Malabsorption of protein bound vitamin B12.

1984 • 73 citations

The Total Serum Homocysteine as an Indicator of Vitamin B12 and Folate Status

1988 • 58 citations

Cobalamin (vitamin B12) deficiency detection by urinary methylmalonic acid quantitation

1982 • 56 citations

Effect of Pepsin on the Absorption of Food Vitamin B12 and Iron

1967 • 33 citations

Experience with pterolyglutamic (synthetic folic) acid in the treatment of pernicious anemia.

1947 • 29 citations

"Improved" vitamin B12 assays: a report on two commercial kits.

1983 • 26 citations

Intrinsic factor studies. IV. Selective absorption and binding of cyanocobalamin by gastric juice in the presence of excess pseudovitamin B12 or 5, 6-dimethylbenzimidazole.

1956 • 22 citations