Polypeptide Chain Elongation in Protein Biosynthesis

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides

1961 • 1,559 citations

RNA Codewords and Protein Synthesis

1964 • 1,400 citations

THE EFFECT OF GUANOSINE DIPHOSPHATE AND TRIPHOSPHATE ON THE INCORPORATION OF LABELED AMINO ACIDS INTO PROTEINS

1956 • 439 citations

Release factors differing in specificity for terminator codons.

1968 • 374 citations

Polypeptide synthesis in Escherichia coli

1963 • 371 citations

Initiation of protein synthesis II a convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin

1966 • 353 citations

ON THE ROLE OF SOLUBLE RIBONUCLEIC ACID IN CODING FOR AMINO ACIDS

1962 • 320 citations

AMINO ACID TRANSFER FROM AMINOACYL-RIBONUCLEIC ACIDS TO PROTEIN ON RIBOSOMES OF ESCHERICHIA COLI

1961 • 301 citations

Myoglobin and the Structure of Proteins

1963 • 285 citations

Catalysis of peptide bond formation by 50 s ribosomal subunits from Escherichia coli

1967 • 272 citations

Ribosome-catalysed reaction of puromycin with a formylmethionine-containing oligonucleotide

1967 • 268 citations

CHARACTERIZATION OF A RIBOSOME-LINKED GUANOSINE TRIPHOSPHATASE IN ESCHERICHIA COLI EXTRACTS

1964 • 245 citations

Conformation of the Anticodon Loop in tRNA

1967 • 231 citations

The interrelationship between guanosine triphosphatase and amino acid polymerization

1966 • 225 citations

Translation of the genetic message

1968 • 218 citations

Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics

1968 • 216 citations

Microorganisms Three Billion Years Old from the Precambrian of South Africa

1966 • 210 citations

Fusidic Acid: a New Antibiotic

1962 • 201 citations

Polypeptide chain termination in vitro: isolation of a release factor.

1967 • 196 citations

Separation of three microbial amino acid polymerization factors.

1966 • 189 citations

Comparison of guanosine triphosphate split and polypeptide synthesis with a purified E. coli system.

1966 • 176 citations

Translocation in Protein Synthesis: A Hybrid Structure Model

1968 • 160 citations

MECHANISM OF PEPTIDE BOND FORMATION IN POLYPEPTIDE SYNTHESIS

1964 • 158 citations

Cyclic dissociation into stable subunits and re-formation of ribosomes during bacterial growth

1968 • 155 citations

Initiation of polyphenylalanine synthesis by N-acetylphenylalanyl-SRNA.

1967 • 155 citations

The Genetic Code--Yesterday, Today, and Tomorrow

1966 • 150 citations

Sequential Translation of Trinucleotide Codons for the Initiation and Termination of Protein Synthesis

1968 • 148 citations

Translation of the genetic message: factors involved in the initiation of protein synthesis.

1966 • 147 citations

Ribosome-catalyzed peptidyl transfer: substrate specificity at the P-site.

1968 • 146 citations

Initiation of Protein Synthesis : a Critical Test of the 30S Subunit Model

1968 • 122 citations

Evidence for aminoacyl-tRNA binding, peptide bond synthesis, and translocase activities in the aminoacyl transfer reaction

1968 • 119 citations

Function of Three Protein Factors and Ribosomal Subunits in the Initiation of Protein Synthesis in E. coli

1968 • 117 citations

Stepwise synthesis of a tripeptide.

1968 • 115 citations

Comparison of amino acid polymerization factors isolated from rat liver and rabbit reticulocytes

1968 • 115 citations

Requirement of granosine 5'-triphosphate for ribosomal binding of aminoacyl-SRNA.

1968 • 111 citations

TRANSLATION OF THE GENETIC MESSAGE, II. EFFECT OF INITIATION FACTORS ON THE BINDING OF FORMYL-METHIONYL-TRNA TO RIBOSOMES

1967 • 108 citations

Peptide Chain Elongation: Discrimination against the Initiator Transfer RNA by Microbial Amino-acid Polymerization Factors

1968 • 107 citations

A GTP Requirement for Binding Initiator tRNA to Ribosomes

1967 • 107 citations

Evidence for a guanine nucleotide-aminoacyl-RNA complex as an intermediate in the enzymatic transfer of aminoacyl-RNA to ribosomes

1967 • 105 citations

The Genetic Code: III

1966 • 95 citations

Suppression of a coat protein mutant of the bacteriophage f2

1965 • 94 citations

A factor from E. coli required for the translation of natural messenger RNA

1966 • 90 citations

Basic Problems in Neoplastic Disease

1963 • 88 citations

A competitive inhibitor of the GTP reaction in protein synthesis

1966 • 86 citations

A possible mechanism for initiation of protein synthesis.

1966 • 84 citations

A stepwise reaction yielding a complex between a supernatant fraction from E. coli, guanosine 5'-triphosphate, and aminoacyl-sRNA.

1968 • 80 citations

Regulation of nucleic acid and protein biosyntheis

1967 • 80 citations

RESOLUTION OF THE E. COLI AMINO ACYL sRNA TRANSFER FACTOR INTO TWO COMPLEMENTARY FRACTIONS

1964 • 79 citations

The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

1967 • 77 citations

Interaction of guanosine 5'-triphosphate with a supernatant fraction from E. coli and aminoacyl-sRNA.

1967 • 72 citations

Crystalline transfer factors from Escherichia coli

1968 • 70 citations

The structure of fusidic acid

1962 • 69 citations

Initiation and protein synthesis: Translation of di- and tri-codon messengers

1968 • 68 citations

GTP interaction with a protein synthesis initiation factor preparation from Escherichiacoli

1967 • 59 citations

Binding of guanosine 5'-triphosphate by soluble factors required for polypeptide synthesis.

1968 • 57 citations

Guanosine triphosphate interaction with an amino acid polymerization factor from E. coli.

1967 • 51 citations

Formation of Peptide Bonds--I: Peptide Formation from Aminoacyl-S-RNA

1963 • 50 citations

Protein synthesis from aminoacyl-soluble ribonucleic acid.

1962 • 48 citations

Polypeptide Chain Termination in Cell-Free Extracts of E. coli

1966 • 44 citations

Amino acids in Precambrian sediments: an assay.

1968 • 41 citations

Synthesis in the study of nucleic acids. The Fourth Jubilee Lecture

1968 • 37 citations

The Genetic Code

1966 • 36 citations

Crystalline G Factor from Escherichia coli

1968 • 36 citations

The fine structure of striated muscle and its functional significance.

1966 • 28 citations

The Fractionation of Transfer Factors in the Presence of a Proteolytic Inhibitor

1968 • 9 citations