Southwestern Internal Medicine Conference: Small Cell Lung Cancer: A Problem of Tumor Heterogeneity

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

Important Advances in Oncology: 1986

1986 • 912 citations

Establishment and identification of small cell lung cancer cell lines having classic and variant features

1986 • 896 citations

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1985 • 843 citations

Rationale for the use of alternating non-cross-resistant chemotherapy.

1982 • 545 citations

MEDICAL RESEARCH COUNCIL COMPARATIVE TRIAL OF SURGERY AND RADIOTHERAPY FOR PRIMARY TREATMENT OF SMALL-CELLED OR OAT-CELLED CARCINOMA OF BRONCHUS

1973 • 528 citations

High Levels of Intracellular Bombesin Characterize Human Small-Cell Lung Carcinoma

1981 • 492 citations

CNS metastases in small cell bronchogenic carcinoma.Increasing frequency and changing pattern with lengthening survival

1979 • 478 citations

Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties.

1985 • 472 citations

Specific Chromosome Defect Associated with Human Small-Cell Lung Cancer: Deletion 3p(14-23)

1982 • 450 citations

Tumor size, sensitivity to therapy, and design of treatment schedules.

1977 • 442 citations

cis-Dichlorodiammineplatinum(II): combination chemotherapy and cross-resistance studies with tumors of mice.

1979 • 405 citations

Alkylating agents in bronchogenic carcinoma

1969 • 353 citations

Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties.

1980 • 317 citations

VP-16 and cisplatin as first-line therapy for small-cell lung cancer.

1985 • 301 citations

The Survival of Patients with Inoperable Lung Cancer: A Large-Scale Randomized Study of Radiation Therapy Versus Placebo

1968 • 293 citations

In vitro radiation and chemotherapy sensitivity of established cell lines of human small cell lung cancer and its large cell morphological variants.

1983 • 282 citations

Surgical resection in the management of small cell carcinoma of the lung

1982 • 255 citations

I. High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer

1985 • 251 citations

Lung cancer heterogeneity: A blinded and randomized study of 100 consecutive cases

1985 • 225 citations

Small cell lung cancer 1973–1983: Early progress and recent obstacles

1984 • 219 citations

Gastrin releasing peptide is a selective mitogen for small cell lung carcinoma in vitro.

1985 • 216 citations

Randomized trial of radiotherapy to the thorax in limited small-cell carcinoma of the lung treated with multiagent chemotherapy and elective brain irradiation: a preliminary report.

1984 • 206 citations

Quantitative model for multiple levels of drug resistance in clinical tumors.

1983 • 191 citations

Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.

1985 • 188 citations

Important advances in oncology 1996

1997 • 184 citations

The clinical behavior of „mixed” small cell/large cell bronchogenic carcinoma compared to „pure” small cell subtypes

1982 • 181 citations

Carcinomatous Leptomeningitis in Small Cell Lung Cancer

1982 • 170 citations

Small cell lung cancer, endocrine cells of the fetal bronchus, and other neuroendocrine cells express the Leu-7 antigenic determinant present on natural killer cells

1985 • 165 citations

cis-Dichlorodiammineplatinum(II) and VP-16-213: an active induction regimen for small cell carcinoma of the lung.

1979 • 153 citations

Radiotherapy in small cell cancer of the lung treated with combination chemotherapy: a controlled trial.

1984 • 140 citations

Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer

1983 • 126 citations

Small cell anaplastic carcinoma of lung.Reappraisal of current management

1976 • 118 citations

Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.

1984 • 114 citations

The prognostic significance of histopathologic subtyping of small cell carcinoma of the lung according to the classification of the world health organization. A study of 375 consecutive patients

1983 • 111 citations

Patients with Small-Cell Lung Cancer Treated with Combination Chemotherapy with or without Irradiation

1985 • 111 citations

The influence of radiation therapy quality control on survival, response and sites of relapse in oat cell carcinoma of the lung. Preliminary report of a Southwest Oncology group study

1982 • 106 citations

Alternating radiotherapy and chemotherapy schedules in small cell lung cancer, limited disease

1985 • 100 citations

Predictors of radiation response in lung cancer.A clinico-pathobiological analysis

1976 • 95 citations

Reduction in local recurrence and improved survival in surgically treated patients with small cell lung cancer

1983 • 92 citations

Monoclonal antibodies that distinguish non-small cell from small cell lung cancer.

1983 • 90 citations

High-dose intensification therapy with autologous bone marrow support for limited small-cell bronchogenic carcinoma.

1986 • 87 citations

“The state of the art” toward defining the role of radiation therapy in the management of small cell bronchogenic carcinoma

1980 • 85 citations

Immunocytochemical Demonstration of Neuron-Specific Enolase (NSE) in Human Lung Cancers

1985 • 84 citations

Thoracic and elective brain irradiation with concomitant or delayed multiagent chemotherapy in the treatment of localized small cell carcinoma of the lung: A randomized prospective study by the southeastern cancer study group

1981 • 80 citations

Small Cell Bronchogenic Carcinoma: A Review of Therapeutic Results

1981 • 74 citations

Long-term survival and toxicity in small cell lung cancer

1984 • 72 citations

Long-term survival in small-cell carcinoma of the lung: a population experience.

1985 • 72 citations

Pathology of small-cell lung cancer

2000 • 69 citations

Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer.

1986 • 66 citations

Diagnosis and typing of lung carcinomas by cytopathologic methods. A review of 108 cases

1986 • 66 citations

High-dose cyclophosphamide in small-cell carcinoma of the lung.

1985 • 65 citations

Results of whole-brain irradiation for metastases from small cell carcinoma of the lung.

1980 • 64 citations

The Feasibility of Adjuvant Surgery in Limited-Stage Small Cell Carcinoma: A Prospective Evaluation

1984 • 62 citations

Phase II trial of extended indications for resection is small cell carcinoma of the lung.

1982 • 61 citations

Differential expression of intermediate filament proteins distinguishes classic from variant small-cell lung cancer cell lines.

1985 • 61 citations

Phase II trial of extended indications for resection in small cell carcinoma of the lung

1982 • 56 citations

The role of radiation therapy in the treatment of small cell lung cancer

1985 • 52 citations

Effect of initial resection of small-cell carcinoma of the lung: a review of Southwest Oncology Group Study 7628.

1985 • 51 citations

Chemotherapy of small-cell carcinoma of lung: a randomized comparison of alternating and sequential combination chemotherapy programs.

1984 • 50 citations

Combined modality therapy with radiotherapy, chemotherapy, and immunotherapy in limited small-cell carcinoma of the lung: a Phase III cancer and Leukemia Group B Study.

1985 • 47 citations

Is chest radiotherapy necessary in any or all patients with small cell carcinoma of the lung? Yes.

1983 • 47 citations

VP-16-213 in combination chemotherapy with chest irradiation for small-cell lung cancer: a randomized trial of the Piedmont Oncology Association.

1984 • 46 citations

Combination chemotherapy in small cell lung carcinoma: A randomized study of two intensive regimens

1984 • 45 citations

Extensive-stage small-cell bronchogenic carcinoma: intensive induction chemotherapy with high-dose cyclophosphamide plus high-dose etoposide.

1985 • 38 citations

What is the lowest effective biologic dose for prophylactic cranial irradiation?

1985 • 35 citations

Treatment policy of surgery in small cell carcinoma of the lung: retrospective analysis of a series of 874 consecutive patients.

1985 • 35 citations

New aspects of clinical drug resistance: the role of gene amplification and the reversal of resistance in drug refractory cancer.

1986 • 35 citations

Frequency, diagnosis, and prognosis of spinal cord compression in small cell bronchogenic carcinoma. A review of 817 consecutive patients

1985 • 34 citations

Human leukocyte interferon as part of a combined treatment for previously untreated small cell lung cancer.

1985 • 33 citations

Combination cyclophosphamide, adriamycin, and vincristine rapidly alternating with combination cisplatin and VP-16 in treatment of small cell lung cancer

1985 • 32 citations

A comparison of computed tomography and radionuclide scanning for detection of brain metastases in small cell lung cancer.

1984 • 32 citations

Potential clinical utility of monoclonal antibodies in the management of human carcinomas.

1985 • 31 citations

Autologous bone marrow transplantation following high-dose chemotherapy with cyclophosphamide, BCNU and VP-16 in small cell carcinoma of the lung and a review of current literature

1984 • 30 citations

Treatment of small cell lung cancer with VP-16, vincristine, doxorubicin (Adriamycin), cyclophosphamide (EVAC), and high-dose chest radiotherapy.

1983 • 30 citations

Characterization of two human small cell lung carcinoma-reactive monoclonal antibodies generated by a novel immunization approach.

1984 • 29 citations

The value of magnetic resonance imaging in assessment of carcinoma of the cervix and its response to radiotherapy

1992 • 28 citations

Changes in the relative risk and sites of central nervous system metastasis with effective combined chemotherapy and radiation therapy for small cell carcinoma of the lung*

1983 • 26 citations

Response to Thoracic Radiotherapy in Patients with Small Cell Carcinoma of the Lung After Failure of Combination Chemotherapy

1979 • 23 citations

Effects of intensive induction chemotherapy for extensive-disease small cell bronchogenic carcinoma in protected environment-prophylactic antibiotic units

1984 • 21 citations

The Role of Surgery in the Treatment of Small Cell Carcinoma of the Lung

1985 • 19 citations

In vitro assays of chemotherapeutic sensitivity.

1985 • 19 citations

Electron microscopy in selection of patients with small cell carcinoma of the lung for medical versus surgical therapy

1985 • 18 citations

Intensive induction chemotherapy for small cell anaplastic carcinoma of the lung

1986 • 18 citations

Role of computerized cranial tomography in the staging of small cell carcinoma of the lung

1985 • 15 citations

Morphologic Changes in Small Cell Lung Cancer

1983 • 5 citations

Histologic alterations in small cell carcinoma of the lung after two cycles of intensive chemotherapy

1984 • 5 citations

26. Radiation Therapy for Primary Tumors of the Spinal Cord

1985 • 5 citations

27. What is the Lowest Effective Biologic Dose for Prophylactic Cranial Irradiation?

1985 • 5 citations

[Surgical treatment of small-cell bronchial carcinoma].

1984 • 2 citations

Transfection of the C-Myc proto-oncogene into classic small cell lung cancer (SCLC) cell lines causes phenotypic changes associated with C-MYC amplified variant SCLC lines

1986 • 2 citations

Transforming Growth Factors (TGFs) and Human Lung Cancer Cells

1983 • 2 citations

Deleted Work

1955 • 0 citations