Metformin increases insulin sensitivity and basal glucose clearance in Type 2 (non‐insulin dependent) diabetes mellitus

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

1979 • 7,240 citations

Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans

1988 • 627 citations

Effect of Metformin on Carbohydrate and Lipoprotein Metabolism in NIDDM Patients

1990 • 263 citations

Disposition of metformin (N,N‐dimethylbiguanide) in man

1978 • 216 citations

Mechanism of Metformin Action in Non-Insulin-Dependent Diabetes

1987 • 184 citations

Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes

1989 • 116 citations

Rates of noninsulin-mediated glucose uptake are elevated in type II diabetic subjects.

1985 • 112 citations

Specific Inhibition of Gluconeogenesis by Biguanides

1967 • 109 citations

Effect of Metformin on Insulin-Stimulated Glucose Turnover and Insulin Binding to Receptors in Type II Diabetes

1987 • 105 citations

Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus.

1986 • 99 citations

Different effects of insulin and oral antidiabetic agents on glucose and energy metabolism in Type 2 (non-insulin-dependent) diabetes mellitus

1989 • 96 citations

Effect of metformin on glucose metabolism in mouse soleus muscle.

1986 • 90 citations

Estimation and kinetic analysis of insulin-independent glucose uptake in human subjects

1983 • 86 citations

Metformin improved insulin resistance in type I, insulin-dependent, diabetic patients

1985 • 82 citations

Mechanism of metformin action in non-insulin-dependent diabetes

1987 • 68 citations

Impaired β-cell Responses Improve when Fasting Blood Glucose Concentration is Reduced in Non-insulin-dependent Diabetes

1988 • 35 citations

THE EFFECTS OF LONG TERM GLICLAZIDE ADMINISTRATION ON INSULIN SECRETION AND INSULIN SENSITIVITY

1989 • 23 citations

Effect of Hyperglycemiaper seon Glucose Disposal and Clearance in Noninsulin-Dependent Diabetics*

1983 • 15 citations

Metformin potentiates the antigluconeogenic action of insulin.

1988 • 14 citations