Mechanism of aminoglycoside-induced lysosomal phospholipidosis: In vitro and in vivo studies with Gentamicin and Amikacin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

The Pharmacological Basis for Therapeutics

1981 • 1,896 citations

Lysosomotropic agents

1974 • 1,887 citations

Lysosomes and storage diseases

1973 • 745 citations

Double-Blind Comparison of the Nephrotoxicity and Auditory Toxicity of Gentamicin and Tobramycin

1980 • 424 citations

Nephrotoxicity of Gentamicin

2015 • 331 citations

Autoradiography of gentamicin uptake by the rat proximal tubule cell

1979 • 307 citations

The Metabolism of Sphingomyelin

1966 • 248 citations

Digestive Activity of Lysosomes

1969 • 246 citations

A light and electron microscopic analysis of gentamicin nephrotoxicity in rats.

1976 • 232 citations

Phospholipid Metabolism

1972 • 184 citations

Gentamicin-induced nephrotoxicity: A cell biology approach

1980 • 165 citations

Enzymatic Hydrolysis of Sphingolipids

1966 • 158 citations

The uptake and intracellular accumulation of aminoglycoside antibiotics in lysosomes of cultured rat fibroblasts

1978 • 152 citations

Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Quantitative ultrastructural and biochemical study.

1979 • 141 citations

The renal handling of polybasic drugs

1977 • 138 citations

Properties of phospholipase C isolated from rat liver lysosomes.

1980 • 128 citations

EFFECT OF NEOMYCIN ON PHOSPHOINOSITIDE LABELLING AND CALCIUM BINDING IN GUINEA‐PIG INNER EAR TISSUES IN VIVO AND IN VITRO¹

1976 • 119 citations

Deficiency of sphingomyelin-cleaving enzyme activity in tissue cultures derived from patients with Niemann-Pick disease

1969 • 90 citations

Interactions of neomycin and calcium in synaptosomal membranes and polyphosphoinositide monolayers

1976 • 79 citations

Lysosomal alterations in cultured macrophages exposed to anorexigenic and psychotropic drugs.

1976 • 70 citations

Phospholipase C activity of rat tissues

1980 • 70 citations

Comparative low-dose nephrotoxicities of gentamicin, tobramycin, and amikacin

1980 • 60 citations

Bis(monoacylglycerin)phosphorsäure-Vermehrung bei Sphingomyelinose (M. NIEMANN-PICK?)

1971 • 54 citations

Comparative toxicity of gentamicin versus tobramycin: a randomized prospective study

1981 • 50 citations

Myeloid bodies in the renal tubules of humans: relationship to gentamicin therapy.

1978 • 50 citations

Drug-Related Syndromes in Clinical Nephrology

1977 • 48 citations

Bis(monoacylglycerin)phosphorsäure — ein Marker-Lipid sekundärer Lysosomen?

1976 • 40 citations

Gentamicin Nephrotoxicity in the Dog: Sequential Light and Electron Microscopy

1980 • 39 citations

Interaction of aminoglycoside antibiotics with phospholipid liposomes studied by microelectrophoresis.

1979 • 37 citations

Cellular Toxicity of Gentamicin

1979 • 36 citations

Hydrolytic degradation of phosphatidylethanolamine and phosphatidylcholine by isolated rat-liver lysosomes

1982 • 35 citations

Drug-Induced Foam Cell Reactions in Rats, II. Chemical Analysis of Lipids Stored in Lungs and Foam Cells after Treatment with Chlorphentermine, 5-[p-(Fluoren-9-ylidenemethyl)phenyl]-2-piperidineethanol (RMI 10.393) and 1-Chloramitriptyline

1975 • 31 citations

Aminoglycoside antibiotics inhibit lysosomal phospholipase A and C from rat liver in vitro

1982 • 28 citations

Studies on Drug-Induced Lipidosis

1977 • 27 citations

Comparative toxicity of aminoglycoside antibiotics towards the lysosomes in a cell culture model

1980 • 20 citations

Prospective comparative study of the nephrotoxicity of aminoglycosides in human (abstract)

1981 • 19 citations

Nephrotoxicity of Gentamicin in the Human-kidney

1980 • 8 citations