IP3 receptor purified from liver plasma membrane is an (1,4,5)IP3 activated and (1,3,4,5)IP4 inhibited calcium permeable ion channel

Inositol phosphates and cell signalling

1989 • 4,058 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

1991 • 1,699 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

[31] Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands

1988 • 1,048 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Purification and reconstitution of the calcium release channel from skeletal muscle

1988 • 928 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum.

1990 • 644 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Purified inositol 1,4,5-trisphosphate receptor mediates calcium flux in reconstituted lipid vesicles

1989 • 512 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Purified ryanodine receptor from skeletal muscle sarcoplasmic reticulum is the Ca2+-permeable pore of the calcium release channel.

1987 • 503 citations

Biochemistry And Biophysics Of Excitation-Contraction Coupling

1989 • 494 citations

[2] Subcellular fractionation of rat liver

1974 • 438 citations

Differential immunohistochemical localization of inositol 1,4,5- trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain

1993 • 435 citations

Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain

1992 • 424 citations

Single channel measurements of the calcium release channel from skeletal muscle sarcoplasmic reticulum. Activation by Ca2+ and ATP and modulation by Mg2+.

1986 • 403 citations

Inositol 1,4,5-trisphosphate activates a channel from smooth muscle sarcoplasmic reticulum

1988 • 399 citations

Ion‐concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction.

1979 • 394 citations

Structure of a novel InsP3 receptor.

1991 • 383 citations

Primary structure and functional expression from cDN A of the cardiac ryanodine receptor/calcium release channel

1990 • 347 citations

Isolation of the ryanodine receptor from cardiac sarcoplasmic reticulum and identity with the feet structures.

1987 • 312 citations

Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum.

1991 • 299 citations

Isolation and characterization of the inositol trisphosphate receptor from smooth muscle.

1990 • 258 citations

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

1992 • 253 citations

Expression of a Ryanodine Receptor-Ca ²⁺ Channel that is Regulated by TGF-β

1992 • 247 citations

Plasma membrane inositol 1,4,5-Trisphosphate-Activated channels mediate signal transduction in lobster olfactory receptor neurons

1992 • 235 citations

Purified ryanodine receptor of skeletal muscle sarcoplasmic reticulum forms Ca2+-activated oligomeric Ca2+ channels in planar bilayers.

1988 • 213 citations

IP ₃ Receptor: Localization to Plasma Membrane of T Cells and Cocapping with the T Cell Receptor

1992 • 213 citations

Structural and Functional Characterization of the Purified Cardiac Ryanodine Receptor-Ca2+ Release Channel Complex

1989 • 209 citations

Calcium flux mediated by purified inositol 1,4,5-trisphosphate receptor in reconstituted lipid vesicles is allosterically regulated by adenine nucleotides.

1990 • 192 citations

Resting and action potentials in experimental bimolecular lipid membranes

1968 • 182 citations

Characterization of inositol 1,4,5-trisphosphate receptors and calcium mobilization in a hepatic plasma membrane fraction.

1988 • 178 citations

Inositol trisphosphate, calcium and muscle contraction

1988 • 137 citations

Multiple conductance states of the purified calcium release channel complex from skeletal sarcoplasmic reticulum

1989 • 115 citations

Different intracellular localization of inositol 1,4,5-trisphosphate and ryanodine receptors in cardiomyocytes.

1993 • 111 citations

The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: Effect of FKBP-12 on single channel activity of the skeletal muscle ryanodine receptor

1994 • 110 citations

Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from skeletal muscle

1994 • 103 citations

Digoxin activates sarcoplasmic reticulum Ca²⁺‐release channels: a possible role in cardiac inotropy

1993 • 93 citations

[11] Planar lipid-protein membranes: Strategies of formation and of detecting dependencies of ion transport functions on membrane conditions

1989 • 83 citations

Inositol 1,4,5-trisphosphate receptor in heart: evidence for its concentration in Purkinje myocytes of the conduction system.

1993 • 83 citations

Purified IP3 receptor from smooth muscle forms an IP3 gated and heparin sensitive Ca2+ channel in planar bilayers

1991 • 73 citations

[3H]PN200-110 and [3H]ryanodine binding and reconstitution of ion channel activity with skeletal muscle membranes

1989 • 71 citations

Smooth muscle and brain inositol 1,4,5-trisphosphate receptors are structurally and functionally similar.

1990 • 68 citations

Inositol 1,4,5-trisphosphate receptors. Localization in epithelial tissue.

1992 • 66 citations

Patch Clamp Studies of Lymphocyte Activation

1990 • 60 citations

Structural and functional characterization of an inositol polyphosphate receptor from cerebellum.

1992 • 45 citations

Different localization of inositol 1,4,5-trisphosphate and ryanodine binding sites in rat liver

1992 • 33 citations

Characterization of Ca2+ fluxes in rat liver plasma-membrane vesicles

1988 • 31 citations