New-onset diabetes and antihypertensive drugs

Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

2002 • 5,558 citations

2003 European Society of Hypertension???European Society of Cardiology guidelines for the management of arterial hypertension*

2003 • 2,946 citations

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial

2005 • 2,895 citations

Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial

2004 • 2,571 citations

2003 European society of hypertension - European Society of Cardiology guidelines for the management of arterial hypertension

2003 • 2,534 citations

Adipokines: inflammation and the pleiotropic role of white adipose tissue

2004 • 2,127 citations

Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial

1999 • 2,051 citations

Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme

2003 • 1,862 citations

Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol

2002 • 1,592 citations

Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study

1999 • 1,472 citations

The Study on Cognition and Prognosis in the Elderly (SCOPE)

2003 • 1,423 citations

A Calcium Antagonist vs a Non–Calcium Antagonist Hypertension Treatment Strategy for Patients With Coronary Artery Disease

2003 • 1,268 citations

Diabetes, Hypertension, and Cardiovascular Disease

2001 • 1,259 citations

Hypertension and Antihypertensive Therapy as Risk Factors for Type 2 Diabetes Mellitus

2000 • 1,180 citations

Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials

2003 • 1,164 citations

A Comparison of Outcomes with Angiotensin-Converting–Enzyme Inhibitors and Diuretics for Hypertension in the Elderly

2003 • 1,135 citations

Angiotensin-Converting–Enzyme Inhibition in Stable Coronary Artery Disease

2004 • 1,106 citations

Randomised trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study

2000 • 923 citations

Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ Activity

2004 • 719 citations

Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease

1994 • 603 citations

Insulin Resistance in Chronic Heart Failure: Relation to Severity and Etiology of Heart Failure

1997 • 534 citations

Adverse Prognostic Significance of New Diabetes in Treated Hypertensive Subjects

2004 • 516 citations

Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study

2002 • 403 citations

Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant Subjects with Cardiovascular Disease (ONTARGET/TRANSCEND) trials

2004 • 385 citations

Diuretic use, progressive heart failure, and death in patients in the studies of left ventricular dysfunction (SOLVD)

2003 • 345 citations

Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes

2004 • 327 citations

Metabolic outcome during 1 year in newly detected hypertensives: results of the Antihypertensive Treatment and Lipid Profile in a North of Sweden Efficacy Evaluation (ALPINE study).

2003 • 317 citations

Prevention Conference VI: Diabetes and Cardiovascular Disease

2002 • 309 citations

Prevention of Type 2 Diabetes Mellitus Through Inhibition of the Renin-Angiotensin System

2004 • 302 citations

Why blockade of the renin–angiotensin system reduces the incidence of new-onset diabetes

2005 • 296 citations

Influence of Long-term, Low-Dose, Diuretic-Based, Antihypertensive Therapy on Glucose, Lipid, Uric Acid, and Potassium Levels in Older Men and Women With Isolated Systolic Hypertension<subtitle>The Systolic Hypertension in the Elderly Program</subtitle>

1998 • 292 citations

Mechanisms of Insulin Resistance in Humans and Possible Links With Inflammation

2005 • 278 citations

Metabolic outcome during 1 year in newly detected hypertensives

2003 • 262 citations

Antidiabetic mechanisms of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists

2004 • 190 citations

Cellular mechanisms of insulin resistance in humans

1999 • 176 citations

Old antihypertensives and new diabetes

2004 • 162 citations

Outcomes With Nifedipine GITS or Co-Amilozide in Hypertensive Diabetics and Nondiabetics in Intervention as a Goal in Hypertension (INSIGHT)

2003 • 158 citations

Do antihypertensive drugs precipitate diabetes?

1984 • 152 citations

Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial

2004 • 150 citations

Impact of Incident Diabetes and Incident Nonfatal Cardiovascular Disease on 18-Year Mortality

2003 • 150 citations

Obesity, hypertension and insulin resistance

2005 • 146 citations

Diabetes and Cardiovascular Events in Hypertensive Patients

1999 • 145 citations

Incidence of Type 2 Diabetes in the Randomized Multiple Risk Factor Intervention Trial

2005 • 141 citations

The association of hypertension and diabetes: prevalence, cardiovascular risk and protection by blood pressure reduction

2005 • 141 citations

Antihypertensive treatment in patients with type-2 diabetes mellitus

2002 • 133 citations

Increase in blood glucose concentration during antihypertensive treatment as a predictor of myocardial infarction: population based cohort study

2003 • 120 citations

The Study on COgnition and Prognosis in the Elderly (SCOPE); outcomes in patients not receiving add-on therapy after randomization

2004 • 105 citations

The diabetogenic potential of thiazide-type diuretic and beta-blocker combinations in patients with hypertension

2005 • 103 citations

Development of diabetes is retarded by ACE inhibition in hypertensive patients--a subanalysis of the Captopril Prevention Project (CAPPP).

2004 • 92 citations

Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II1 1This is a US government work. There are no restrictions on its use.

2004 • 88 citations

Long-term metabolic effects of antihypertensive drugs

1994 • 86 citations

Antihypertensive therapy and new onset diabetes

2004 • 64 citations

Effect of insulin-plus-glucose infusion with or without epinephrine on fasting hyperkalemia

1993 • 58 citations

Novel Pharmacologic Agents for Type 2 Diabetes

2005 • 45 citations

Effect of Long-Term Treatment with Antihypertensive Drugs on Quality of Life of Elderly Patients with Hypertension: A Double-Blind Comparative Study between a Calcium Antagonist and a Diuretic.

2000 • 43 citations

Diabetes and Hypertension

2001 • 40 citations

Treatment Strategy to Control Blood Pressure Optimally in Hypertensive Patients

2001 • 35 citations

Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity.

2003 • 26 citations

Metabolic effects of antihypertensive treatment

2003 • 10 citations

The role of drugs in countering adverse pathophysiological profiles: Influence on hemodynamics

1987 • 6 citations