Physical studies of tyrosine and tryptophan residues in mammalian A1 heterogeneous nuclear ribonucleoprotein Support for a segmented structure

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Prediction of protein conformation

1974 • 3,327 citations

Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide

1985 • 1,191 citations

Prediction of chain flexibility in proteins

1985 • 1,123 citations

The antigenic index: a novel algorithm for predicting antigenic determinants

1988 • 655 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

Heterogeneous Nuclear Ribonucleoproteins: Role in RNA Splicing

1986 • 399 citations

Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence.

1987 • 393 citations

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression

1986 • 389 citations

Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts.

1989 • 236 citations

Construction and performance of a variable-frequency phase-modulation fluorometer

1985 • 231 citations

Rotational freedom of tryptophan residues in proteins and peptides

1983 • 218 citations

Purification and physical characterization of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 211 citations

The Biology of Nonspecific DNA Protein Interactions

1990 • 195 citations

Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif

1987 • 187 citations

A Comparative Study of Polydeoxyribonucleotides and Polyribonucleotides by Optical Rotatory Dispersion^*

1966 • 187 citations

Interactions of Oligopeptides With Nucleic Acid

1981 • 180 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

Structure of rodent helix-destabilizing protein revealed by cDNA cloning.

1986 • 173 citations

Mammalian heterogeneous nuclear ribonucleoprotein complex protein A1. Large-scale overproduction in Escherichia coli and cooperative binding to single-stranded nucleic acids.

1988 • 170 citations

The dynamics of populating and depopulating the phosphorescent triplet state as studied by microwave induced delayed phosphorescence

1971 • 170 citations

The Eukaryotic nucleus : Molecular biochemistry and macromolecular assemblies

1990 • 148 citations

Refined structure of the gene 5 DNA binding protein from bacteriophage fd

1983 • 143 citations

Purification and domain structure of core hnRNP proteins A1 and A2 and their relationship to single-stranded DNA-binding proteins.

1986 • 123 citations

Nucleic acid helix-coil transitions mediated by helix-unwinding proteins from calf thymus.

1976 • 109 citations

Single-stranded DNA structure and DNA polymerase activity in the presence of nucleic acid helix-unwinding proteins from calf thymus.

1976 • 109 citations

Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1.

1986 • 107 citations

pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.

1987 • 89 citations

Phosphorescence and optically detected magnetic resonance studies of a class of anomalous tryptophan residues in globular proteins

1980 • 82 citations

Amino acid sequence of the UP1 calf thymus helix-destabilizing protein and its homology to an analogous protein from mouse myeloma.

1985 • 82 citations

Investigation of the role of individual tryptophan residues in the binding of Escherichia coli single-stranded DNA binding protein to single-stranded polynucleotides. A study by optical detection of magnetic resonance and site-selected mutagenesis.

1987 • 77 citations

Resolution of tryptophan phosphorescence from multiple sites in proteins using optical detection of magnetic resonance

1974 • 70 citations

Tryptophan 54 and phenylalanine 60 are involved synergistically in the binding of E. coli SSB protein to single‐stranded polynucleotides

1987 • 64 citations

Luminescence and Electron Spin Resonance Studies of Adenine in Various Polynucleotides

1966 • 58 citations

Mammalian heterogeneous nuclear ribonucleoprotein A1. Nucleic acid binding properties of the COOH-terminal domain.

1990 • 53 citations

Direct measurement of spin-lattice relaxation rates between triplet spin sublevels using optical detection of magnetic resonance

1974 • 52 citations

Proton NMR (500 MHz) identification of aromatic residues of gene 32 protein involved in DNA binding by use of protein containing perdeuterated aromatic residues and by site-directed mutagenesis

1986 • 52 citations

Entry site of formylmethionyl‐tRNA

1972 • 52 citations

Methylmercury as a spin-orbit probe. Effect of complexing on the excited state properties of tryptophan, tryptamine, and benzimidazole

1978 • 46 citations

Study of triplet-singlet energy transfer in an enzyme-dye complex using optical detection of magnetic resonance

1976 • 42 citations

Site-specific mutagenesis of T4 gene 32: the role of tyrosine residues in protein.cntdot.nucleic acid interactions

1989 • 40 citations

Study of the triplet state properties of tyrosines and tryptophan in azurins using optically detected magnetic resonance

1977 • 36 citations

Stacking interactions of tryptophan residues and nucleotide bases in complexes formed between Escherichia coli single-stranded DNA binding protein and heavy atom-modified poly(uridylic) acid. A study by optically detected magnetic resonance spectroscopy.

1987 • 30 citations

Physical studies of the interaction of a calf thymus helix-destabilizing protein with nucleic acids

1980 • 28 citations

Triplet state properties of tryptophan residues in complexes of mutated Escherichia coli single-stranded DNA binding proteins with single-stranded polynucleotides

1989 • 28 citations

Effect of stacking interactions with poly(riboadenylic acid) on the triplet state properties of tryptophan

1978 • 24 citations

Optically detected magnetic resonance of tryptophan residues in Escherichia coli ssb gene product and E. coli plasmid-encoded single-stranded DNA-binding proteins and their complexes with poly(deoxythymidylic) acid.

1987 • 24 citations

Investigation of complexes formed between gene 32 protein from bacteriophage T4 and heavy-atom-modified single-stranded polynucleotides using optical detection of magnetic resonance

1986 • 18 citations

Optically detected magnetic resonance of tryptophan residues in complexes formed between a bacterial single-stranded DNA binding protein and heavy atom-modified poly(uridylic acid)

1987 • 16 citations

Involvement of tryptophyl residues in the binding of model peptides and gene 32 protein from phage T4 to single-stranded polynucleotides. A spectroscopic method for detection of tryptophan in the vicinity of nucleic acid bases

1984 • 14 citations

Role of tryptophan and cysteine in the binding of gene 32 protein from phage T4 to single-stranded DNA. Modification of crucial residues by oxidation with selective free-radical anions

1984 • 12 citations

A maximum of two tryptophan residues in gene‐32 protein from phage T4 undergo stacking interactions with single‐stranded polynucleotides

1988 • 11 citations

Comparison of cooperative and isolated site binding of T4 gene 32 protein to ssDNA by proton NMR

1989 • 10 citations

Fluorescence studies on the role of tryptophan in heterogeneous nuclear ribonucleoprotein particles of HeLa cells

1989 • 4 citations