Relevance of interstrand DNA crosslinking induced by anthracyclines for their biological activity
Data up to Jan 2025
Total Citations Per Year
Abstract
References (29)
The Logic of Scientific Discovery
2013 • 8,086 citations
An Introduction to Statistical Methods and Data Analysis
1994 • 5,244 citations
A fluorometric method for determination of oxidized and reduced glutathione in tissues
1976 • 4,013 citations
An Introduction to Statistical Methods and Data Analysis.
1983 • 626 citations
Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion
1985 • 545 citations
Doxorubicin (adriamycin): A critical review of free radical-dependent mechanisms of cytotoxicity
1990 • 512 citations
The Logic of Scientific Discovery.
1977 • 360 citations
Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and biological review
1984 • 223 citations
DNA topoisomerase II-mediated interaction of doxorubicin and daunorubicin congeners with DNA.
1989 • 219 citations
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
1993 • 194 citations
Metabolism and action of anti-cancer drugs
1987 • 161 citations
DNA topoisomerase II as the primary target of anti-tumor anthracyclines.
1990 • 160 citations
Potentiation of doxorubicin cytotoxicity by buthionine sulfoximine in multidrug-resistant human breast tumor cells.
1989 • 128 citations
Isolation and characterization of a human colon adenocarcinoma cell line resistant to doxorubicin
1986 • 119 citations
Cell surface actions of adriamycin
1991 • 109 citations
Structure-activity relationships of anthracyclines relative to effects on macromolecular syntheses.
1978 • 96 citations
G2 block induced by DNA crosslinking agents and its possible consequences
1988 • 96 citations
Reviews in biochemical toxicology
1984 • 67 citations
Redox chemistry of anthracycline antitumor drugs and use of captodative radicals as tools for its elucidation and control
1991 • 46 citations
Anthracycline and anthracenedione based anticancer agents
1990 • 46 citations
Relationship of adriamycin concentrations to the DNA lesions induced in hypoxic and euoxic L1210 cells.
1983 • 45 citations
Effect of D,L-buthionine-S,R-sulfoximine on cytotoxicity and DNA cross-linking induced by bifunctional DNA-reactive cytostatic drugs in human melanoma cells.
1988 • 43 citations
Glutathione conjugation: Mechanisms and biological significance
1989 • 40 citations
Adriamycin and daunomycin induce interstrand DNA crosslinks in HeLa S3 cells
1983 • 40 citations
DNA polymerases and DNA topoisomerases as targets for the development of anticancer drugs.
1986 • 33 citations
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
1984 • 28 citations
Joint experimental and theoretical investigation of the comparative DNA binding affinities of intercalating anthracycline derivatives.
1989 • 27 citations
Effect of the methylation of aglycone hydroxyl groups on the biological and biochemical properties of daunorubicin
1981 • 24 citations
Isolation of two Chinese hamster ovary cell mutants hypersensitive to topoisomerase II inhibitors and cross-resistant to peroxides.
1989 • 8 citations