The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Physiology and pharmacology of corticotropin-releasing factor.

1991 • 1,138 citations

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

1991 • 943 citations

Altered Expression of Hypothalamic Neuropeptide mRNAs in Food-Restricted and Food-Deprived Rats

1990 • 648 citations

Neurosteroids act on recombinant human GABAA receptors

1990 • 515 citations

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.

1988 • 459 citations

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1991 • 454 citations

Mediation by Corticotropin Releasing Factor (CRF) of Adenohypophysial Hormone Secretion

1986 • 443 citations

Biochemistry, Molecular Biology, and Physiology of the Glucocorticoid Receptor*

1987 • 409 citations

Quantitative in situ hybridization histochemistry reveals increased levels of corticotropin-releasing factor mRNA after adrenalectomy in rats

1986 • 377 citations

Progestin Receptors in Rat Brain: Distribution and Properties of Cytoplasmic Progestin-Binding Sites*

1980 • 342 citations

Progesterone receptor-mediated effects of neuroactive steroids

1993 • 297 citations

Synthesis, metabolism, and pharmacological activity of 3.alpha.-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes

1990 • 295 citations

Effects of Adrenalectomy and Dexamethasone Administration on the Level of Prepro-Corticotropin-Releasing Factor Messenger Ribonucleic Acid (mRNA) in the Hypothalamus and Adrenocorticotropin/β-Lipotropin Precursor mRNA in the Pituitary in Rats*

1985 • 274 citations

The Role of Corticotropin‐Releasing Factor in Behavioural Responses to Stress

2007 • 235 citations

Further Evidence for a Central Stimulatory Action of Catecholamines on Adrenocorticotropin Release in the Rat

1987 • 222 citations

Cloning and sequence analysis of cDNA for rat corticotropin‐releasing factor precursor

1985 • 211 citations

Adrenalectomy-induced enhancement of CRF and vasopressin immunoreactivity in parvocellular neurosecretory neurons: anatomic, peptide, and steroid specificity

1987 • 206 citations

Expression and Estrogen Regulation of Progesterone Receptor mRNA in Neurons of the Mediobasal Hypothalamus: Anin SituHybridization Study

1989 • 203 citations

Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test

1985 • 195 citations

Anxiolytic Metabolites of Progesterone: Correlation with Mood and Performance Measures following Oral Progesterone Administration to Healthy Female Volunteers

1993 • 161 citations

Chapter 21 The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia

1992 • 160 citations

Immunocytochemical localization of estrogen-induced progestin receptors in guinea pig brain

1988 • 146 citations

Adrenergic mechanisms in the control of corticotrophin secretion

1988 • 129 citations

Sexual dimorphism of glucocorticoid binding in rat brain

1985 • 129 citations

Analgesic effects of the progesterone metabolite, 3α-hydroxy-5α-pregnan-20-one, and possible modes of action in mice

1987 • 112 citations

Corticotropin-releasing factor

1993 • 94 citations

In vitro study of immunoreactive corticotropin-releasing factor release from the rat hypothalamus

1985 • 87 citations

Participation of α<sub>1</sub>-Adrenergic Receptors in the Secretion of Hypothalamic Corticotropin- Releasing Hormone during Stress

1992 • 87 citations

Acute effects of alprazolam and adinazolam on the concentrations of corticotropin‐releasing factor in the rat brain

1989 • 86 citations

Regulation of Hypophysiotropic Factors Mediating ACTH Secretiona

1987 • 84 citations

Changes in the Hypothalamo-Corticotrope Axis after Bilateral Adrenalectomy: Evidence for a Median Eminence Site of Glucocorticoid Action

1991 • 78 citations

Gene expression for estrogen and progesterone receptor mRNAS in rat brain and possible relations to sexually dimorphic functions

1991 • 71 citations

Glucocorticoid Receptors: Evidence for a Second, Non-Glucocorticoid Binding Site

1976 • 68 citations

The influence of corticosteroids on the secretion of corticotrophin and its hypothalamic releasing hormone

1979 • 53 citations

Anxiolytic and anxiogenic drugs: Changes in behaviour and endocrine responses

1988 • 50 citations

Increased plasma concentrations, hypothalamic content, and in vitro release of arginine vasopressin in inflammatory disease-prone, hypothalamic corticotropin-releasing hormone-deficient Lewis rats.

1992 • 50 citations

Pregnane steroid alphaxalone attenuates anxiogenic behavioral effects of corticotropin releasing factor and stress

1992 • 47 citations

Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus.

1992 • 47 citations

Thymic hormone-containing cells. VII. Adrenals and gonads control the in vivo secretion of thymulin and its plasmatic inhibitor.

1986 • 43 citations

Steroid Hormones and Receptors of the GABA<sub>A</sub> Supramolecular Complex

1993 • 38 citations

Increased plasma concentrations, hypothalamic content, and in vitro release of arginine vasopressin in inflammatory disease-prone, hypothalamic corticotropin-releasing hormone-deficient Lewis rats

1992 • 26 citations

Progestin receptor in the thymus of ovariectomized immature rats

1985 • 25 citations

Second Messenger Regulation of mRNA for Corticotropin‐Releasing Factor

2007 • 25 citations

Adrenalectomy and Experimental Hypercorticalism Modulate the Basal, Corticotropin-Releasing-Hormone- and Arginine-Vasopressin-Stimulated Release of Hypothalamic Beta-Endorphin

1991 • 25 citations

Sexual dimorphism in regulation of type II corticosteroid receptor immunoreactivity in the rat hippocampus

1992 • 13 citations

Neurosteroids: an overview.

1992 • 13 citations

Gamma‐Aminobutyric Acid Modulation of Corticotrophin‐Releasing Factor‐41 Secretion from the Rat Hypothalamus in vitro

1990 • 11 citations

Deleted Work

1955 • 0 citations