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Drug discrimination in pentylenetetrazol‐trained baboons: Generalization to buspirone and β‐carboline‐3‐carboxylic acid ethyl ester but not lorazepam or pentobarbital

Data up to Jan 2025

Published1989
Citations17
References26

Total Citations Per Year

Abstract

References (26)

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1986 • 2,365 citations

Buspirone

1986 • 330 citations

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1982 • 314 citations

Behavioral analogues of anxiety animal models

1983 • 180 citations

Dopamine receptor antagonism by the novel antianxiety drug, buspirone

1983 • 159 citations

Piperazine derivatives including the putative anxiolytic drugs, buspirone and ipsapirone, are agonists at 5-HT1A receptors negatively coupled with adenylate cyclase in hippocampal neurons

1987 • 136 citations

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1986 • 76 citations

Discriminative stimulus properties of pentylenetetrazol and bemegride: Some generalization and antagonism tests

1979 • 76 citations

Lorazepam and pentobarbital drug discrimination in baboons: cross-drug generalization and interaction with Ro 15-1788.

1983 • 73 citations

Discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OHDPAT): implications for understanding the actions of novel anxiolytics

1987 • 71 citations

Discriminative stimulus properties of buspirone compared to central nervous system depressants in rats

1983 • 69 citations

Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.

1985 • 68 citations

Discriminative stimulus effects of atypical anxiolytics in baboons and rats.

1986 • 68 citations

Generalization and antagonism studies with convulsant, GABAergic and anticonvulsant drugs in rats trained to discriminate pentylenetetrazol from saline

1980 • 63 citations

Discriminative stimulus properties of buspirone in the pigeon.

1987 • 53 citations

β-Carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat

1984 • 51 citations

Antagonism of discriminative stimuli produced by anxiogenic drugs as a novel approach to bioassay anxiolytics

1984 • 49 citations

The pentylenetetrazol model of anxiety detects withdrawal from diazepam in rats

1983 • 48 citations

Antagonism of benzodiazepine receptors by beta carbolines

1981 • 41 citations

Lorazepam and pentobarbital discrimination: Interactions with CGS 8216 and caffeine

1985 • 32 citations

Discriminative and aversive properties of β-carboline-3-carboxylic acid ethyl ester, a benzodiazepine receptor inverse agonist, in rhesus monkey

1986 • 31 citations

Pentylenetetrazol May Discriminate Between Different Types of Benzodiazepine Receptors

1983 • 31 citations

Buspirone-induced jitteriness in three patients with panic disorder and one patient with generalized anxiety disorder.

1988 • 13 citations

Nonbenzodiazepine anxiolytics: insights into possible mechanisms of action.

1986 • 9 citations

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Drug discrimination in pentylenetetrazol‐trained baboons: Generalization to buspirone and… (1989) – Drug Development Research | Metascience Observatory Explorer