Controversies in stroke: past and present. The Willis Lecture.

Beneficial Effect of Carotid Endarterectomy in Symptomatic Patients with High-Grade Carotid Stenosis

1991 • 8,040 citations

MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis

1991 • 3,163 citations

PLACEBO-CONTROLLED, RANDOMISED TRIAL OF WARFARIN AND ASPIRIN FOR PREVENTION OF THROMBOEMBOLIC COMPLICATIONS IN CHRONIC ATRIAL FIBRILLATION

1989 • 1,845 citations

Stroke Prevention in Atrial Fibrillation Study. Final results.

1991 • 1,695 citations

The Effect of Low-Dose Warfarin on the Risk of Stroke in Patients with Nonrheumatic Atrial Fibrillation

1990 • 1,503 citations

Efficacy of Carotid Endarterectomy for Asymptomatic Carotid Stenosis

1993 • 1,403 citations

A Randomized Trial Comparing Ticlopidine Hydrochloride with Aspirin for the Prevention of Stroke in High-Risk Patients

1989 • 1,209 citations

The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results.

1991 • 1,145 citations

Methods for combining randomized clinical trials: Strengths and limitations

1987 • 998 citations

Carotid Endarterectomy and Prevention of Cerebral Ischemia in Symptomatic Carotid Stenosis

1991 • 962 citations

THE CANADIAN AMERICAN TICLOPIDINE STUDY (CATS) IN THROMBOEMBOLIC STROKE

1989 • 912 citations

A Comparison of Two Doses of Aspirin (30 mg vs. 283 mg a Day) in Patients after a Transient Ischemic Attack or Minor Ischemic Stroke

1991 • 747 citations

Controlled trial of aspirin in cerebral ischemia.

1977 • 633 citations

"AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia.

1983 • 615 citations

Carotid surgery versus medical therapy in asymptomatic carotid stenosis. The CASANOVA Study Group.

1991 • 344 citations

Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group.

1985 • 284 citations

Anticoagulant therapy in cerebral infarction

1962 • 263 citations

Meta‐analysis of clinical trials as a scientific discipline. I: Control of bias and comparison with large co‐operative trials

1987 • 245 citations

Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin.

1992 • 210 citations

Acetylsalicylic acid in the prevention of stroke in patients with reversible cerebral ischemic attacks. A Danish cooperative study.

1983 • 192 citations

High-dose acetylsalicylic acid after cerebral infarction. A Swedish Cooperative Study.

1987 • 180 citations

Controlled trial of aspirin in cerebral ischemia. Part II: surgical group.

1978 • 171 citations

Optimal Therapeutic Range for Oral Anticoagulants

1989 • 155 citations

Double‐blind study of the effects of dexamethasone on acute stroke

1972 • 142 citations

Steroid Therapy in Acute Cerebral Infarction

1976 • 140 citations

Assessing risk associated with carotid endarterectomy. A statement for health professionals by an Ad Hoc Committee on Carotid Surgery Standards of the Stroke Council, American Heart Association.

1989 • 121 citations

Dexamethasone as Treatment in Cerebrovascular Disease. 2. A Controlled Study in Acute Cerebral Infarction

1973 • 121 citations

Dramatic changes in the performance of endarterectomy for diseases of the extracranial arteries of the head.

1988 • 112 citations

Decreased Platelet Membrane Fluidity Due to Glycation or Acetylation of Membrane Proteins

1992 • 112 citations

An evaluation of anticoagulant therapy in the treatment of cerebrovascular disease

1961 • 109 citations

Antiplatelet drugs and generation of thrombin in clotting blood

1992 • 108 citations

Transient ischemic strokes

1966 • 100 citations

LONG-TERM ANTICOAGULANT THERAPY IN TRANSIENT CEREBRAL ISCHÆMIC ATTACKS

1965 • 92 citations

Epidemiology of carotid endarterectomies among Medicare beneficiaries

1992 • 87 citations

EVALUATION OF CORTISONE IN THE TREATMENT OF CEREBRAL INFARCTION

1956 • 72 citations

CORTISONE IN IMMEDIATE THERAPY OF APOPLECTIC STROKE

1955 • 58 citations

Risks of carotid endarterectomy. Toronto Cerebrovascular Study Group.

1986 • 54 citations

Differential Effect of Aspirin on Platelet Aggregation in IDDM

1992 • 51 citations

Antiplatelet Treatment Prolongs Survival After Carotid Bifurcation Endarterectomy

1990 • 45 citations

THE INFLUENCE OF ADRENOCORTICAL STEROIDS ON SEVERE CEREBROVASCULAR ACCIDENTS

1965 • 44 citations

Dose‐Dependent Aspirin Hydrolysis and Platelet Aggregation in Patients with Atherosclerosis

1992 • 19 citations

Antiplatelet therapy following carotid bifurcation endarterectomy. Evaluation of a controlled clinical trial. Prognostic significance of histologic plaque examination on behalf of survival

1990 • 15 citations

Toward an optimal “antiplatelet” dose of aspirin: Preliminary observations

1991 • 14 citations

NEW TREATMENT FOR HEREDITARY (HUNTINGTON) CHOREA

1952 • 9 citations

ORAL PROCAINE AMIDE TREATMENT OF HUNTINGTON??S CHOREA

1954 • 5 citations