The folding funnel landscape for the peptide met-enkephalin

Possible generalization of Boltzmann-Gibbs statistics

1988 • 8,734 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Funnels, pathways, and the energy landscape of protein folding: A synthesis

1995 • 2,607 citations

RASMOL: biomolecular graphics for all

1995 • 2,601 citations

New Monte Carlo technique for studying phase transitions

1988 • 2,556 citations

Optimized Monte Carlo data analysis

1989 • 2,506 citations

From Levinthal to pathways to funnels

1997 • 2,277 citations

THEORY OF PROTEIN FOLDING: The Energy Landscape Perspective

1997 • 2,102 citations

Spin glasses and the statistical mechanics of protein folding.

1987 • 1,608 citations

Monte Carlo-minimization approach to the multiple-minima problem in protein folding.

1987 • 1,419 citations

Multicanonical algorithms for first order phase transitions

1991 • 1,151 citations

New approach to Monte Carlo calculation of the free energy: Method of expanded ensembles

1992 • 1,011 citations

Protein folding funnels: a kinetic approach to the sequence-structure relationship.

1992 • 923 citations

Parallel tempering algorithm for conformational studies of biological molecules

1997 • 913 citations

The double cubic lattice method: Efficient approaches to numerical integration of surface area and volume and to dot surface contouring of molecular assemblies

1995 • 906 citations

Kinetics of Protein Folding

1994 • 572 citations

Toward an outline of the topography of a realistic protein-folding funnel.

1995 • 510 citations

Diffusive dynamics of the reaction coordinate for protein folding funnels

1996 • 436 citations

First-Principles Calculation of the Folding Free Energy of a Three-Helix Bundle Protein

1995 • 392 citations

Prediction of peptide conformation by multicanonical algorithm: New approach to the multiple‐minima problem

1993 • 385 citations

Kinetics and thermodynamics of folding in model proteins.

1993 • 371 citations

Kinetics of protein folding: Nucleation mechanism, time scales, and pathways

1995 • 348 citations

Intermolecular potentials from crystal data. 6. Determination of empirical potentials for O-H...O = C hydrogen bonds from packing configurations

1984 • 343 citations

Folding funnels and frustration in off-lattice minimalist protein landscapes

1998 • 331 citations

Thermodynamics of Helix-Coil Transitions Studied by Multicanonical Algorithms

1995 • 193 citations

Protein folding mechanisms and the multidimensional folding funnel

1998 • 186 citations

Conformational Energy Calculations on Polypeptides and Proteins

1994 • 181 citations

Numerical comparisons of three recently proposed algorithms in the protein folding problem

1997 • 168 citations

Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability

1997 • 165 citations

Kinetics and Thermodynamics of Folding of ade NovoDesigned Four-helix Bundle Protein

1996 • 163 citations

Comparative study of multicanonical and simulated annealing algorithms in the protein folding problem

1994 • 126 citations

Factors governing the foldability of proteins

1996 • 120 citations

Generalized-ensemble Monte Carlo method for systems with rough energy landscape

1997 • 112 citations

Thermodynamics of protein folding: A statistical mechanical study of a small all-β protein

1997 • 110 citations

Non-Markovian Configurational Diffusion and Reaction Coordinates for Protein Folding

1998 • 110 citations

Universality and diversity of the protein folding scenarios:a comprehensive analysis with the aid of a lattice model

1996 • 109 citations

Efficient search for all low energy conformations of polypeptides by Monte Carlo methods

1991 • 106 citations

Fast-folding eriments and the topography of protein folding energy landscapes

1996 • 99 citations

Exploring the space of protein folding Hamiltonians: The balance of forces in a minimalist β-barrel model

1998 • 99 citations

THE GENERALIZED-ENSEMBLE APPROACH FOR PROTEIN FOLDING SIMULATIONS

1999 • 94 citations

A crystal molecular conformation of leucine‐enkephalin related to the morphine molecule

1989 • 94 citations

Generalized protein tertiary structure recognition using associative memory hamiltonians

1991 • 78 citations

Finite-size scaling of helix–coil transitions in poly-alanine studied by multicanonical simulations

1999 • 73 citations

Characteristic temperatures of folding of a small peptide

1997 • 71 citations

Annual Reviews of Computational Physics VI

1999 • 64 citations

Evidence for a folded conformation of methionine- and leucine-enkephalin in a membrane environment.

1984 • 63 citations

Prediction of α-Helix Folding of Isolated C-Peptide of Ribonuclease A by Monte Carlo Simulated Annealing

1991 • 63 citations

Backbone dynamics, fast folding, and secondary structure formation in helical proteins and peptides

1999 • 63 citations

A reexamination of the double‐helix model for agarose gels using optical rotation

1995 • 46 citations

Variation of the Energy Landscape of a Small Peptide under a Change from the ECEPP/2 Force Field to ECEPP/3

1997 • 46 citations

Prediction of Low-Energy Structures of Met-Enkephalin by Monte Carlo Simulated Annealing

1992 • 43 citations

Tertiary Structure Prediction of C-Peptide of Ribonuclease A by Multicanonical Algorithm

1998 • 41 citations

Effects of Side-Chain Charges on α-Helix Stability in C-Peptide of Ribonuclease A Studied by Multicanonical Algorithm

1999 • 39 citations

Simulated annealing with Tsallis weights a numerical comparison

1997 • 30 citations

A criterion that determines fast folding of proteins: A model study

1996 • 29 citations

¹⁷O‐ and ¹⁴N‐nmr studies of Leu‐enkephalin and enkephalin‐related fragments in aqueous solution

1990 • 22 citations

Simulated annealing of met-enkephalin: low energy states and their relevance to membrane-bound, solution and solid-state conformations

1994 • 21 citations