The Reaction Mechanism for CD38. A Single Intermediate Is Responsible for Cyclization, Hydrolysis, and Base-Exchange Chemistries

Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.

1990 • 344 citations

Inhibition of Spleen Diphosphopyridine Nucleotidase by Nicotinamide, An Exchange Reaction

1953 • 271 citations

Enzymatic synthesis and characterizations of cyclic GDP-ribose. A procedure for distinguishing enzymes with ADP-ribosyl cyclase activity.

1994 • 244 citations

Nitric Oxide-induced Mobilization of Intracellular Calcium via the Cyclic ADP-ribose Signaling Pathway

1996 • 230 citations

Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38

1992 • 228 citations

Involvement of the multilineage CD38 molecule in a unique pathway of cell activation and proliferation.

1990 • 220 citations

Interaction between endothelium and CD4+CD45RA+ lymphocytes. Role of the human CD38 molecule.

1994 • 159 citations

Ligation of CD38 suppresses human B lymphopoiesis.

1995 • 150 citations

The Type 2 Ryanodine Receptor of Neurosecretory PC12 Cells Is Activated by Cyclic ADP-ribose

1996 • 119 citations

Ultrastructural localization of CD38 immunoreactivity in rat brain

1997 • 110 citations

Human CD38 is an authentic NAD(P)+ glycohydrolase

1998 • 109 citations

Human CD38 ligand. A 120-KDA protein predominantly expressed on endothelial cells.

1996 • 106 citations

Enzyme Properties of Aplysia ADP-Ribosyl Cyclase: Comparison with NAD Glycohydrolase of CD38 Antigen1

1995 • 63 citations

Mechanism of Cyclization of Pyridine Nucleotides by Bovine Spleen NAD+ Glycohydrolase

1996 • 53 citations

Calf‐Spleen Nicotinamide‐Adenine Dinucleotide Glycohydrolase Kinetic Mechanism

1976 • 47 citations

Chemical evidence in favor of a stabilized oxocarbonium-ion intermediate in the NAD+ glycohydrolase-catalyzed reactions

1988 • 41 citations

The stereochemistry of calf spleen NAD‐glycohydrolase‐catalyzed NAD methanolysis

1976 • 41 citations

Enzymic Synthesis of NAD+ with the Specific Incorporation of Atomic Labels

1994 • 40 citations

Mapping of the catalytic and epitopic sites of human CD38/NAD+ glycohydrolase to a functional domain in the carboxyl terminus.

1997 • 40 citations

THEORY OF THE TRANSIENT PHASE IN AN ENZYME SYSTEM INVOLVING TWO ENZYME-SUBSTRATE COMPLEXES: THE CASE OF THE FORMATION OF PRODUCTS FROM THE FIRST COMPLEX

1959 • 39 citations

THEORY OF THE TRANSIENT PHASE IN KINETICS, WITH SPECIAL REFERENCE TO ENZYME SYSTEMS: II. THE CASE OF TWO ENZYME–SUBSTRATE COMPLEXES

1956 • 25 citations

Synthesis and applications of 8-azido photoaffinity analogs of P1,P3-bis(5′-adenosyl)triphosphate and P1,P4-bis(5′-adenosyl)tetraphosphate

1990 • 22 citations